1698-60-8

• 常用中文名：5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮
• 常用英文名：Chloridazon
• CAS号：1698-60-8
• 分子式：C₁₀H₈ClN₃O
• 分子量：221.643
• 相关类别： 有机原料 有机膦化合物
• 发布时间：2018-09-03 18:18:33
• 更新时间：2024-01-04 10:30:41

• 用作钻井泥浆添加剂
  
  

名称

• 中文名: 氯草敏
• 英文名: chloridazon
• 中文别名: 5-氨基-4-氯-2-苯基哒嗪-3-酮; 1-苯基-4-氨基-5-氯-6-哒唑; 5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮; 杀草敏
• 英文别名: 5-Amino-4-chlor-2-phenylpyridazin-3(2H)-on; Chloridazon; pyrazon; 3(2H)-Pyridazinone, 5-amino-4-chloro-2-phenyl-; MFCD00055402; PYRAMIN; 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one; 5-Amino-4-chloro-2-phenyl-2H-pyridazin-3-one; PAC; EINECS 216-920-2; 5-Amino-4-chloro-2-phenyl-3(2H)-pyridazinone; Chloridazon,Pyrazone; Poly (acrylic acid-co-hypophosphite) sodium salt

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 312.2±52.0 °C at 760 mmHg
• 熔点: 206ºC (tech., 198-202ºC)
• 分子式: C₁₀H₈ClN₃O
• 分子量: 221.643
• 闪点: 142.6±30.7 °C
• 精确质量: 221.035583
• PSA: 60.91000
• LogP: 0.73
• 外观性状: 无色,无臭固体,(硬脂酸正丁酯,棕色,近乎于无臭固体)
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.668
• 储存条件:

  0-6°C密封储存

• 水溶解性: 水溶性：不溶；水溶解度：400 mg/l 20 °C；可溶于：甲醇；微溶：丙酮；不溶：二氯甲烷,苯,甲苯,氯仿,乙醚
• 分子结构:

  1、 摩尔折射率：57.90

  2、 摩尔体积（m³/mol）：155.4

  3、 等张比容（90.2K）：426.4

  4、 表面张力（dyne/cm）：56.6

  5、 介电常数（F/m）：无可用

  6、 极化率（10 ^-24cm ³）：22.95

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:3

  4.可旋转化学键数量:1

  5.互变异构体数量:3

  6.拓扑分子极性表面积58.7

  7.重原子数量:15

  8.表面电荷:0

  9.复杂度:332

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1. 性状：淡黄色固体。

  2. 密度（g/mL,25/4℃）： 未确定

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：205-206

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC,5.2kPa）： 未确定

  7. 折射率： 未确定

  8. 闪点（ºC）： 未确定

  9. 比旋光度（º）： 未确定

  10. 自燃点或引燃温度（ºC）： 未确定

  11. 蒸气压（kPa,25ºC）： 未确定

  12. 饱和蒸气压（kPa,60ºC）： 未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）： 未确定

  15. 临界压力（KPa）： 未确定

  16. 油水（辛醇/水）分配系数的对数值： 未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）： 未确定

  19. 溶解性：微溶于水，能溶于丙酮、甲醇和苯。

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UR6125000 CHEMICAL NAME : 3(2H)-Pyridazinone, 5-amino-4-chloro-2-phenyl- CAS REGISTRY NUMBER : 1698-60-8 BEILSTEIN REFERENCE NO. : 0397241 LAST UPDATED : 199706 DATA ITEMS CITED : 26 MOLECULAR FORMULA : C10-H8-Cl-N3-O MOLECULAR WEIGHT : 221.66 WISWESSER LINE NOTATION : T6NNVJ BR& DG EZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration into the eye SPECIES OBSERVED : Rodent - rabbit TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 647 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >30800 mg/m3/4H TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 194 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1410 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 598 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 235 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1205 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - muscle contraction or spasticity TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 2500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 493 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Mammal - species unspecified DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 162 gm/kg/2Y-C TOXIC EFFECTS : Musculoskeletal - other changes TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 30 gm/kg/30D-I TOXIC EFFECTS : Related to Chronic Data - death TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 6006 mg/kg/13W-C TOXIC EFFECTS : Liver - changes in liver weight Endocrine - changes in thyroid weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 10 mg/m3/4H/17W-I TOXIC EFFECTS : Liver - other changes Blood - changes in other cell count (unspecified) Blood - changes in leukocyte (WBC) count TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 142 gm/kg/92W-C TOXIC EFFECTS : Liver - changes in liver weight TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 10 mg/m3/4H/17W-I TOXIC EFFECTS : Liver - other changes Blood - changes in other cell count (unspecified) Blood - changes in leukocyte (WBC) count TYPE OF TEST : TCLo - Lowest published toxic concentration ROUTE OF EXPOSURE : Inhalation DOSE : 1 mg/m3/4H SEX/DURATION : male 72 week(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous DOSE : 175 mg/kg SEX/DURATION : female 8 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) MUTATION DATA TEST SYSTEM : Rodent - rat DOSE/DURATION : 50 mg/m3 REFERENCE : GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 50(1),80,1985 *** REVIEWS *** TOXICOLOGY REVIEW DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970. Volume(issue)/page/year: 80,485,1973 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

安全

• 符号: GHS07, GHS09
• 信号词: Warning
• 危害声明: H317-H410
• 警示性声明: P273-P280-P501
• 个人防护装备: dust mask type N95 (US);Eyeshields;Faceshields;Gloves
• 危害码 (欧洲): Xi: Irritant;N: Dangerous for the environment;
• 风险声明 (欧洲): R43;R50/53
• 安全声明 (欧洲): S24-S37-S60-S61
• 危险品运输编码: 3077
• RTECS号: UR6125000
• 海关编码: 2933990017

合成路线

1698-53-9 ~63% 1698-60-8 1698-61-9

文献：Collection of Czechoslovak Chemical Communications, , vol. 50, # 2 p. 492 - 502

1698-53-9 99-96-7 ~% 1698-60-8

文献：US4454318 A1, ;

156-38-7 1698-53-9 ~% 1698-60-8

文献：US4454318 A1, ;

98-67-9 ~% 1698-60-8

文献：US4454318 A1, ;

上下游产品

上游产品  4
1698-53-9 99-96-7 156-38-7 98-67-9
下游产品  2
30578-37-1 13589-77-0

海关

海关编码	2933990017
中文概述	2933990017 唑草酯,四环唑,恶草酸等〔包括喹禾糠酯,哒草特,咯草隆,禾草敌,唑草胺,敌草快,氯草敏〕。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
监管条件	S.进出口农药登记证明
Summary	2933990017 6,7-dihydrodipyrido[1,2-a:2',1'-c]pyrazine-5,8-diium bromide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%