10025-77-1

• 常用中文名：六水三氯化铁
• 常用英文名：Ferric chloride hexahydrate
• CAS号：10025-77-1
• 分子式：Cl₃FeH₁₂O₆
• 分子量：270.296
• 相关类别： 无机化工 无机盐 金属卤化物及卤酸盐 金属氯化物及盐
• 发布时间：2018-04-24 08:00:00
• 更新时间：2024-01-02 16:13:14
• 【用途一】
  主要用作水处理剂、印刷制版的腐蚀剂、染料工业的氧化剂和媒染剂、有机合成的催化剂以及制造其他铁盐等
  【用途二】
  营养增补剂(铁质强化剂)。用于婴儿奶粉、离乳食品等。
  【用途三】
  分析试剂，测定砷、锂、锡、硒、钒、硫氰酸盐，铁氰酸盐和血清总胆固醇等，工业上用作照相制版，颜料和催化剂等，氧化剂。

名称

• 中文名: 六水三氯化铁
• 英文名: iron trichloride hexahydrate
• 中文别名: 六水合氯化铁; 氯化铁,六水
• 英文别名: Ferric chloride hexahydrate; Iron(3+) chloride hydrate (1:3:6); MFCD00149712; Iron(III) chloride hexahydrate; iron(3+),trichloride,hexahydrate; Iron chloride hexahydrate; EINECS 231-729-4

物化性质

• 密度: 1,82 g/cm3
• 沸点: 280-285 °C(lit.)
• 熔点: 37 °C(lit.)
• 分子式: Cl₃FeH₁₂O₆
• 分子量: 270.296
• 闪点: 280-285°C
• 精确质量: 268.904877
• PSA: 55.38000
• LogP: 2.01770
• 外观性状: 黄色或橙色结块
• 蒸汽压: 1 mm Hg ( 194 °C)
• 储存条件:

  常温密闭避光，通风干燥处;设备要密封。贮运中严防有毒物质污染、雨淋和受潮。装卸时要小心轻放，防止包装破裂而受潮。失火时，可用水、沙土、各种灭火器扑救。

• 稳定性:

  1.有潮解性，在空气中可潮解成红棕色液体。0℃时在100g水中的溶解度为246g，在温水中溶解度更大。能图Ⅷ2溴化亚铁制备装置溶解于乙醇、丙酮、乙醚和甘油。置于潮湿空气中或见光分解生成氯化氢，其水溶液由于水解而呈黄褐色。

• 水溶解性: 920 g/L (20 ºC)
• 分子结构:

  1、摩尔折射率：无可用的

  2、摩尔体积（cm³/mol）：无可用的

  3、等张比容（90.2K）：无可用的

  4、表面张力（dyne/cm）：无可用的

  5、介电常数：无可用的

  6、极化率（10^-24cm³）：无可用的

  7、单一同位素质量：268.904888 Da

  8、标称质量：269 Da

  9、平均质量：270.2957 Da

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:6

  3.氢键受体数量:9

  4.可旋转化学键数量:0

  5.互变异构体数量:无

  6.拓扑分子极性表面积6

  7.重原子数量:10

  8.表面电荷:0

  9.复杂度:0

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:10

• 更多:

  1. 性状：红褐色至黄色的六方晶系结晶，无臭，有涩味，具潮解性。

  2. 密度（g/mL,25℃）：2.898

  3. 熔点（ºC）：282

  4. 沸点（ºC,常压）：280～285

  5. 闪点（ºC）：280-285

  6. 溶解性：溶于水919g/L，溶于乙醇、乙醚。其水溶液呈强酸性，可使蛋白质凝固919g/L

MSDS

Name: Iron(iii) chloride hexahydrate p.a. Material Safety Data Sheet Synonym: Ferric chloride hexahydrat CAS: 10025-77-1 Section 1 - Chemical Product MSDS Name:Iron(iii) chloride hexahydrate p.a. Material Safety Data Sheet Synonym:Ferric chloride hexahydrat Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 10025-77-1 Iron(III) chloride hexahydrate p.a. unlisted Hazard Symbols: C Risk Phrases: 22 34 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful if swallowed. Causes burns.Hygroscopic (absorbs moisture from the air). Potential Health Effects Eye: Causes eye burns. Skin: Causes skin burns. Ingestion: Harmful if swallowed. Causes gastrointestinal tract burns. Inhalation: Causes chemical burns to the respiratory tract. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid immediately. Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid immediately. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Get medical aid immediately. Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Substance is noncombustible. Extinguishing Media: Use extinguishing media most appropriate for the surrounding fire. Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Do not breathe dust, vapor, mist, or gas. Do not get in eyes, on skin, or on clothing. Use only in a chemical fume hood. Storage: Store in a cool, dry place. Store in a tightly closed container. Corrosives area. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 10025-77-1: Belgium - TWA: (listed as iron salts (soluble)): 1 mg/m3 VLE (as Malaysia: (listed as iron salts (soluble)): 1 mg/m3 TWA (as Fe) Netherlands: (listed as iron salts (soluble)): 1 mg/m3 MAC (as Fe Spain: (listed as iron salts (soluble)): 1 mg/m3 VLA-ED (as Fe) Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder and chunks Color: orange Odor: Not available. pH: 2 (0.1 M in water) Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: 280 - 285 deg C @760 mmHg Freezing/Melting Point: 37 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: 920 g/l (20C) Specific Gravity/Density: Molecular Formula: Cl3Fe.6H2O Molecular Weight: 270.29 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable. Conditions to Avoid: Incompatible materials, dust generation, excess heat, exposure to moist air or water. Incompatibilities with Other Materials: Strong oxidizing agents, alkali metals, allyl chloride, ethylene oxide, potassium, sodium. Hazardous Decomposition Products: Hydrogen chloride, oxides of iron. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 10025-77-1: NO5425000 LD50/LC50: Not available. Carcinogenicity: Iron(III) chloride hexahydrate - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Ecotoxicity: logPOW: -4 Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: CORROSIVE SOLID, ACIDIC, INORGANIC, N.O.S.* Hazard Class: 8 UN Number: 3260 Packing Group: III IMO Shipping Name: CORROSIVE SOLID, ACIDIC, INORGANIC, N.O.S. Hazard Class: 8 UN Number: 3260 Packing Group: III RID/ADR Shipping Name: CORROSIVE SOLID, ACIDIC, INORGANIC, N.O.S. Hazard Class: 8 UN Number: 3260 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: C Risk Phrases: R 22 Harmful if swallowed. R 34 Causes burns. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face protection. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 10025-77-1: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 10025-77-1 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 10025-77-1 is not on the TSCA Inventory because it is a hydrate. It is considered to be listed if the CAS number for the anhydrous form is on the inventory (40CFR720.3(u)(2)). SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

毒理学数据: 1、急性毒性：大鼠经口LDLo：900 mg/kg；小鼠腹腔LC50：260 mg/kg；兔子注射LDLo：7200 ug/kg；小鼠经口LC50：14700 mg/kg。刺激皮肤、眼睛。吸入会引起咽痛、腹痛、腹泻、恶心等。工作人员应作好防护。误服后，应用清水清洗口腔，多喝牛奶。 生态学数据: 通常对水体是稍微有害的，不要将未稀释或大量产品接触地下水，水道或污水系统，未经政府许可勿将材料排入周围环境。 CHEMICAL IDENTIFICATION RTECS NUMBER : NO5425000 CHEMICAL NAME : Iron(3+) chloride, hexahydrate CAS REGISTRY NUMBER : 10025-77-1 LAST UPDATED : 199703 DATA ITEMS CITED : 14 MOLECULAR FORMULA : Cl3-Fe.6H2-O MOLECULAR WEIGHT : 270.32 WISWESSER LINE NOTATION : FE G3 &QH 6 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 900 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 260 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 7200 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 61250 mg/kg/14W-C TOXIC EFFECTS : Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases TYPE OF TEST : Micronucleus test MUTATION DATA TYPE OF TEST : Cytogenetic analysis TEST SYSTEM : Rodent - rat Ascites tumor DOSE/DURATION : 500 mg/kg REFERENCE : GANNA2 Gann. Japanese Journal of Cancer Research. (Tokyo, Japan) V.1-75, 1907-84. For publisher information, see JJCREP. Volume(issue)/page/year: 54,155,1963 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 1 mg(Fe)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,138,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 1 mg(Fe)/m3 JAN 1993 OEL-FINLAND:TWA 1 mg(Fe)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 1 mg(Fe)/m3 JAN 1993 OEL-SWITZERLAND:TWA 1 mg(Fe)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 1 mg(Fe)/m3;STEL 2 mg(Fe)/m3 JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4675 No. of Facilities: 100 (estimated) No. of Industries: 4 No. of Occupations: 4 No. of Employees: 871 (estimated) No. of Female Employees: 465 (estimated)

安全

• 符号: GHS05, GHS07
• 信号词: Danger
• 危害声明: H290-H302-H315-H318
• 警示性声明: P280-P305 + P351 + P338
• 危害码 (欧洲): Xn:Harmful
• 风险声明 (欧洲): R22;R38;R41
• 安全声明 (欧洲): S26-S39
• 危险品运输编码: UN 3260 8/PG 3
• WGK德国: 1
• RTECS号: NO5425000
• 包装等级: III
• 危险类别: 8
• 海关编码: 28273300

制备

工业生产有盐酸法和一步氯化法。

1.盐酸法 将盐酸和洗净的铁屑加入反应器中进行反应，生成二氯化铁溶液，经澄清后，把氯气通入清液进行氯化反应，生成三氯化铁溶液，加入除砷剂和除重金属剂进行溶液提纯，过滤除去杂质，再澄清，把清液冷却结晶，固液分离、干燥，制得食用六水三氯化铁成品，其反应方程式如下：

以铁屑或铁粉、盐酸为原料，反应完毕后，经冷却结晶，析出棕黄色粒状三氯化铁结晶。 2.用铁丝或铁粉溶于低于计算量的盐酸中（必要时可加热）。滤去不溶物。往生成的氯化亚铁水溶液中通入氯气，直至发出氯气的臭味为止。或者用硝酸氧化，然后与浓盐酸一起反复蒸发，直至不再显NO-3的反应为止。此时二价铁离子已完全氧化为三价铁离子而不需再检验有残存二价铁离子［例如用六氰合铁（Ⅲ）酸钾K3［Fe（CN）6］水溶液进行试验即可］。将上面制得的氯化铁水溶液蒸发浓缩，至溶液冷却后全部变为固体时为止。由于浓缩过程中氯化氢不断损失，故需经常通入氯化氢。
食用生产用.盐酸法

海关

海关编码	28273300