1151665-15-4

• 常用中文名：2-氯-7,8-二氢-1,6-萘啶-6(5H)-羧酸1,1-二甲基乙酯
• 常用英文名：tert-butyl 2-chloro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate
• CAS号：1151665-15-4
• 分子式：C₁₃H₁₇ClN₂O₂
• 分子量：268.739
• 发布时间：2018-12-27 17:21:14
• 更新时间：2024-01-04 19:20:17

名称

• 中文名: 2-氯-7,8-二氢-1,6-萘啶-6(5H)-羧酸 1,1-二甲基乙酯
• 英文名: tert-Butyl 2-chloro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate
• 中文别名: 叔丁基2-氯-1,8-二氢-1-2,6-萘啶-6(5H)-甲酸叔丁酯
• 英文别名: 2-Methyl-2-propanyl 2-chloro-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate; tert-butyl 2-chloro-7,8-dihydro-5H-1,6-naphthyridine-6-carboxylate; 1,6-Naphthyridine-6(5H)-carboxylic acid, 2-chloro-7,8-dihydro-, 1,1-dimethylethyl ester

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 372.9±42.0 °C at 760 mmHg
• 分子式: C₁₃H₁₇ClN₂O₂
• 分子量: 268.739
• 闪点: 179.3±27.9 °C
• 精确质量: 268.097870
• PSA: 42.43000
• LogP: 2.12
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.548
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

766545-20-4 24424-99-5 ~99% 1151665-15-4

文献：Li, Zhihong; Wang, Xianghong; Eksterowicz, John; Gribble, Michael W.; Alba, Grace Q.; Ayres, Merrill; Carlson, Timothy J.; Chen, Ada; Chen, Xiaoqi; Cho, Robert; Connors, Richard V.; Degraffenreid, Michael; Deignan, Jeffrey T.; Duquette, Jason; Fan, Pingchen; Fisher, Benjamin; Fu, Jiasheng; Huard, Justin N.; Kaizerman, Jacob; Keegan, Kathleen S.; Li, Cong; Li, Kexue; Li, Yunxiao; Liang, Lingming; Liu, Wen; Lively, Sarah E.; Lo, Mei-Chu; Ma, Ji; McMinn, Dustin L.; Mihalic, Jeffrey T.; Modi, Kriti; Ngo, Rachel; Pattabiraman, Kanaka; Piper, Derek E.; Queva, Christophe; Ragains, Mark L.; Suchomel, Julia; Thibault, Steve; Walker, Nigel; Wang, Xiaodong; Wang, Zhulun; Wanska, Malgorzata; Wehn, Paul M.; Weidner, Margaret F.; Zhang, Alex J.; Zhao, Xiaoning; Kamb, Alexander; Wickramasinghe, Dineli; Dai, Kang; McGee, Lawrence R.; Medina, Julio C. Journal of Medicinal Chemistry, 2014 , vol. 57, # 8 p. 3430 - 3449

210539-04-1 24424-99-5 ~73% 1151665-15-4

文献：Takeda Pharmaceutical Company Limited Patent: EP2216023 A1, 2010 ; Location in patent: Page/Page column 103 ; EP 2216023 A1

上下游产品

上游产品  3
766545-20-4 24424-99-5 210539-04-1
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海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%