1064-48-8

• 常用中文名：氨基黑10B
• 常用英文名：Acid Black 1
• CAS号：1064-48-8
• 分子式：C₂₂H₁₄N₆Na₂O₉S₂
• 分子量：616.491
• 相关类别： 染料及颜料 染料 酸性染料
• 发布时间：2018-03-16 08:00:00
• 更新时间：2024-01-03 08:31:21
• 氨基黑10B(萘酚蓝黑)是一种用于氨基酸染色的剧毒偶氮染料。氨基黑10B会在人体呼吸系统中产生若干问题,也可能引起皮肤和眼睛刺激[1]。

名称

• 中文名: 酸性黑 1
• 英文名: Amido Black 10B
• 中文别名: 萘酚蓝; 萘黑10B; 酸性黑1/氨基黑10B; 酸性黑1; 氨基黑10B
• 英文别名: Black 10B; Vondamol Light Black 10B; Dinatrium-4-amino-5-hydroxy-3-[(E)-(4-nitrophenyl)diazenyl]-6-[(E)-phenyldiazenyl]-2,7-naphthalendisulfonat; Fast Sulon Black BN; Metamine Blue Black; Amido Black 10 B; KURO401; Naphtocard Black 12B; aniline blue black; CI NO 0470; Fast Sulfon Black BN; Sodium 4-amino-5-hydroxy-3-(4-nitrophenylazo)-6-(phenylazo)naphthalene-2,7-disulphonate; Comacid Blue Black B; Calcocid Blue Black 2R; 4-Amino-5-hydroxy-3-[(E)-(4-nitrophényl)diazènyl]-6-[(E)-phényldiazènyl]-2,7-naphtalènedisulfonate de disodium; Disodium 4-amino-5-hydroxy-3-[(E)-(4-nitrophenyl)diazenyl]-6-[(E)-phenyldiazenyl]-2,7-naphthalenedisulfonate; Kayaku Acid Blue Black 10B; Naphthylamine Black 10BR; Wool Navy Blue 2B; DermBlueP; Airedale Black 2BG; Fenazo Blue Black; acidblackh; Acid Brown 187; Naphthazine Blue Black 6BN; Acidal Black 10B; Amacid Black 10BR; Napthol Blue Black; Brasilan Black BS; naphthol blue-black; MFCD00004017; Buffalo Black NBR; Amido Black Staining; 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-3-[(E)-2-(4-nitrophenyl)diazenyl]-6-[(E)-2-phenyldiazenyl]-, sodium salt (1:2); 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-3-((4-nitrophenyl)azo)-6-(phenylazo)-, disodium salt; Aniline blue-black; Aminoschwarz 10B; Acid Blue Black B; Pontacyl Blue Black SX; Hispacid Black 10B; Eriosin Blue Black B; AMIDO BLACK; Mitsui Acid Blue Black; Acilan Black 10B; Acid Black 1; Acidal Navy Blue 3BR; naphtol blue black; Boruta Black A; Leather Black 10B; Colacid Black 10A; Naphthol Blue Black; Tertracid Blue Black NB; EINECS 213-903-1; Bucacid Blue Black; 2,7-naphthalenedisulfonic acid, 4-amino-5-hydroxy-3-[(E)-(4-nitrophenyl)azo]-6-[(E)-phenylazo]-, disodium salt; Java Blue Black 10B; Amido Schwarz; ACID BLACK; Hidacid Blue Black; Disodium 4-amino-5-hydroxy-3-[(E)-(4-nitrophenyl)diazenyl]-6-[(E)-phenyldiazenyl]naphthalene-2,7-disulfonate; Calcocid Blue Black; Diacid Blue Black 10B

物化性质

• 密度: 1.05 g/mL at 20 °C
• 分子式: C₂₂H₁₄N₆Na₂O₉S₂
• 分子量: 616.491
• 闪点: 30 °C
• 精确质量: 616.005920
• PSA: 272.67000
• LogP: 7.94080
• 外观性状: 暗红色至黑色粉末
• 储存条件:

  1.密封干燥保存。

• 稳定性:

  1.常温常压下稳定，避免氧化物接触

  2.水溶液加浓盐酸生成绿光蓝色沉淀； 加氢氧化钠溶液生成蓝色沉淀

  3.避免吸入本品的粉尘，避免了与眼睛及皮肤接触。

• 水溶解性: 10 G/L (25 ºC)
• 分子结构:

  1、摩尔折射率：无可用的

  2、摩尔体积（cm³/mol）：无可用的

  3、等张比容（90.2K）：无可用的

  4、表面张力（dyne/cm）：无可用的

  5、介电常数：无可用的

  6、极化率（10^-24cm³）：无可用的

  7、单一同位素质量：616.005906 Da

  8、标称质量：616 Da

  9、平均质量：616.4909 Da

• 计算化学:

  1、 氢键供体数量：2

  2、 氢键受体数量：14

  3、 可旋转化学键数量：4

  4、 互变异构体数量：26

  5、 拓扑分子极性表面积（TPSA）：250

  6、 重原子数量：41

  7、 表面电荷：0

  8、 复杂度：1230

  9、 同位素原子数量：0

  10、 确定原子立构中心数量：0

  11、 不确定原子立构中心数量：0

  12、 确定化学键立构中心数量：1

  13、 不确定化学键立构中心数量：0

  14、 共价键单元数量：3

• 更多:

  1. 性状：黑褐色粉末。

  2. 密度（g/mL,20℃）： 1.05 3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）： 未确定

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC,5.2kPa）：未确定

  7. 折射率：未确定

  8. 闪点（ºC）： 30

  9. 比旋光度（º）： 未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（kPa,25ºC）：未确定

  12. 饱和蒸气压（kPa,60ºC）： 未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）： 未确定

  16. 油水（辛醇/水）分配系数的对数值：

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：可溶于水，水溶液呈蓝黑色，加入浓盐酸产生绿光蓝色沉淀；加入氢氧化钠溶液产生蓝色沉淀。溶于乙醇，呈蓝色，微溶于丙酮，不溶于其他有机溶剂。于浓硫酸中呈蓝光绿色，稀释后产生暗绿光蓝色沉淀；于浓硝酸中呈暗绿色溶液后转变为酱红色；于 10%氢氧化钠溶液中产生蓝色沉淀。染色时，遇铜离子色泽略有变化；遇铁离子色泽略带浅绿。

生物活性

• 描述: 氨基黑10B(萘酚蓝黑)是一种用于氨基酸染色的剧毒偶氮染料。氨基黑10B会在人体呼吸系统中产生若干问题,也可能引起皮肤和眼睛刺激[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Angelova R, et al. Magnetically modified sheaths of Leptothrix sp. as an adsorbent for Amido black 10B removal. Journal of Magnetism and Magnetic Materials, 2017, 427: 314-319.

MSDS

Name: Acid Black 1 Material Safety Data Sheet Synonym: Naphthol blue black; Amido Schwarz CAS: 1064-48-8 Section 1 - Chemical Product MSDS Name:Acid Black 1 Material Safety Data Sheet Synonym:Naphthol blue black; Amido Schwarz Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 1064-48-8 C.I. Acid Black 100.0% 213-903-1 Hazard Symbols: XN Risk Phrases: 20/21 33 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation and in contact with skin. Danger of cumulative effects.The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: Causes eye irritation. May cause chemical conjunctivitis. Skin: Causes skin irritation. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Inhalation: Causes respiratory tract irritation. Can produce delayed pulmonary edema. Chronic: Effects may be delayed. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid. Wash clothing before reuse. Flush skin with plenty of soap and water. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Use with adequate ventilation. Avoid contact with eyes, skin, and clothing. Avoid contact with eyes. Keep container tightly closed. Avoid ingestion and inhalation. Wash clothing before reuse. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 1064-48-8: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: black Odor: Not available pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not applicable. Flash Point: Not applicable. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Not available. Solubility in water: Not available. Specific Gravity/Density: Not available. Molecular Formula: C22H14N6O9S2Na2 Molecular Weight: 616.48 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, none reported, excess heat. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Oxides of nitrogen, oxides of sulfur, irritating and toxic fumes and gases. Hazardous Polymerization: Has not been reported. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 1064-48-8: QJ6196000 LD50/LC50: Not available. Carcinogenicity: C.I. Acid Black - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21 Harmful by inhalation and in contact with skin. R 33 Danger of cumulative effects. Safety Phrases: S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 1064-48-8: 1 Canada CAS# 1064-48-8 is listed on Canada's DSL List. CAS# 1064-48-8 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 1064-48-8 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 对水是稍微有害的，不要让未稀释或大量的产品接触地下水，水道或者污水系统，若无政府许可，勿将材料排入周围环境储存 CHEMICAL IDENTIFICATION RTECS NUMBER : QJ6196000 CHEMICAL NAME : 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-3-((4-nitrophenyl)azo)-6-(phenylazo )-, disodium salt CAS REGISTRY NUMBER : 1064-48-8 LAST UPDATED : 199701 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C22-H16-N6-O9-S2.2Na MOLECULAR WEIGHT : 618.54 HEALTH HAZARD DATA ACUTE TOXICITY DATA MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 50 ug/plate REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 22,188,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81698 No. of Facilities: 591 (estimated) No. of Industries: 10 No. of Occupations: 23 No. of Employees: 6615 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81698 No. of Facilities: 1816 (estimated) No. of Industries: 20 No. of Occupations: 45 No. of Employees: 51898 (estimated) No. of Female Employees: 26897 (estimated)

安全

• 符号: GHS02, GHS07
• 信号词: Warning
• 危害声明: H226-H315-H319-H336
• 警示性声明: P261-P305 + P351 + P338
• 个人防护装备: dust mask type N95 (US);Eyeshields;Gloves
• 危害码 (欧洲): Xi:Irritant
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36-37/39-45-36/37/39-23-16
• 危险品运输编码: UN 2924 3/PG 3
• WGK德国: 3
• RTECS号: QJ6196000
• 危险类别: 3.0
• 海关编码: 3204120000

上下游产品

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制备

1.对硝基苯胺重氮化,与H酸偶合得单偶氮化合物.将苯胺重氮化,与上述单偶化合物偶合而得原料消耗(kg/t)H酸（100%） 240 亚硝酸钠 107对硝基苯胺（100%） 110 碳酸钠（98%） 192苯胺（99%） 66 氢氧化钠（100%）83 .

以 H 酸、对硝基苯胺、苯胺为原料，首先将对硝基苯胺重氮化，于酸性条件下与 H 酸偶合，然后将苯胺重氮化，于碱性条件下与前述偶合产物进行第二次偶合即得产物。经盐析、过滤、干燥、粉碎得成品。

海关

海关编码	3204120000