102507-13-1

• 常用中文名：N-BOC-3-羟基-L-缬氨酸
• 常用英文名：(2S)-2-(N-tert-Butoxycarbonyl)amino-3-hydroxy-3-methylbutanoic acid
• CAS号：102507-13-1
• 分子式：C₁₀H₁₉NO₅
• 分子量：233.262
• 相关类别： 生物化工 氨基酸及其衍生物 缬氨酸类衍生物
• 发布时间：2018-12-18 09:57:04
• 更新时间：2026-07-06 14:04:33

名称

• 中文名: N-Boc-3-羟基-L-缬氨酸
• 英文名: (2S)-3-hydroxy-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
• 中文别名: BOC-(S)-2-氨基-3-羟基-3-甲基丁酸; BOC-(S)-2-氨基-3-羟基-3-甲基丁酸/BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID; N-[叔丁氧羰基]-3-甲基-L-苏氨酸; (S)-2-((叔丁氧基羰基)氨基)-3-羟基-3-甲基丁酸; (S)-2-Boc-氨基-3-羟基-3-甲基丁酸; N-BOC-3-羟基-L-缬氨酸/(S)-2-((TERT-BUTOXYCBONYL)AMINO)-3-HYDROXY-3-METHYLBUTANOIC ACID; (S)-2-((叔丁氧羰基)氨基)-3-羟基-3-甲基丁酸
• 英文别名: N-boc-3-hydroxy-L-valine; (S)-2-N-BOC-AMINO-3-HYDROXY-3-METHYLBUTYRIC ACID; L-Threonine,N-[(1,1-diMethylethoxy)carbonyl]-3-Methyl; boc-l-ser(3,3-dimethyl); BOC-L-SER(3,3-DIMETHYL); (S)-N-Boc-2-Amino-3-hydroxy-3-Methylbutanoic acid; (S)-Boc-beta-hydroxy-valine; (2S)-2-(tert-butoxycbonylamino)-3-hydroxy-3-methyl-butanoic acid; (2S)-2-(N-t-butoxycarbonyl)amino-3-hydroxy-3-methylbutanoic acid; N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID //BP; (S)-2-Boc-amino-3-hydroxy-3-methylbutyric acid; N-(tert-Butoxycbonyl)-3-hydroxy-L-valine; 3-Hydroxy-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valine; n-boc-(s)-2-amino-3-hydroxy-3-methylbutanoic acid; BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID; Boc-3-Methyl-L-threonine; (2S)-2-(N-tert-Butoxycbonyl)amino-3-hydroxy-3-Methylbutanoic acid; N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID; (2S)-3-hydroxy-3-methyl-2-[(2-methylpropan-2-yl)oxycbonylamino]butanoic acid; (2S)-3-hydroxy-3-methyl-2-[(2-methylpropan-2-yl)oxycbonylamino]butanoicaci; Boc-3-hydroxy-L-Valine; (S)-N-ALPHA-T-BUTYLOXYCBONYL-3,3-DIMETHYL-SERINE; N-[(1,1-Dimethylethoxy)carbonyl]-3-methyl-L-threonine; N-[(1,1-Dimethylethoxy)Carbonyl]-3-Methyl-L-Threonine; (S)-N-Boc-2-Amino-3-hydroxy-3-methylbutanoic acid; (S)-2-BOC-AMINO-3-HYDROXY-3-METHYLBUTYRIC ACID; (2S)-3-hydroxy-3-methyl-2-[(2-methylpropan-2-yl)oxycb; (S)-Boc-beta,beta-dimethyl-serine; (S)-2-N-BOC-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID; N-(tert-Butoxycbonyl)-3-hydroxy-L-valine, (2S)-2-Amino-3-hydroxy-3-methylbutanoic acid, N-BOC protected; (S)-2-((tert-Butoxycarbonyl)amino)-3-hydroxy-3-methylbutanoic acid; 3-Hydroxy-L-valine, N-BOC protected; BOC-S-SER(3,3ME2)-OH; N-BOC-3-Methyl-L-threonine; N-(tert-Butoxycarbonyl)-3-hydroxy-L-valine; (S)-Boc-2-amino-3-hydroxy-3-Methyl-butyric acid; N-Boc-3-hydroxy-L-valine; L-Threonine,N-[(1,1-dimethylethoxy)carbonyl]-3-methyl; EOS-60980; (S)-2-N-Boc-amino-3-hydroxy-3-methylbutyric acid

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 391.1±37.0 °C at 760 mmHg
• 熔点: 116-118℃
• 分子式: C₁₀H₁₉NO₅
• 分子量: 233.262
• 闪点: 190.3±26.5 °C
• 精确质量: 233.126328
• PSA: 95.86000
• LogP: 0.91
• 蒸汽压: 0.0±2.0 mmHg at 25°C
• 折射率: 1.483
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): 36/37/38
• 安全声明 (欧洲): 26-36/37/39
• 海关编码: 2924199090

合成路线

473545-40-3 ~97% 102507-13-1

文献：Angewandte Chemie - International Edition, , vol. 50, # 5 p. 1168 - 1170

288159-36-4 ~80% 102507-13-1

文献：Bioorganic and Medicinal Chemistry, , vol. 21, # 14 p. 3996 - 4003

75-16-1 95715-85-8 ~80% 102507-13-1

文献：Journal of Organic Chemistry, , vol. 68, # 1 p. 177 - 179

2280-27-5 34619-03-9 ~67% 102507-13-1

文献：WO2004/54974 A2, ; Page 199 ; WO 2004/054974 A2

95715-85-8 ~% 102507-13-1

文献：Synthesis, , # 5 p. 634 - 636

108149-60-6 ~% 102507-13-1

文献：Synthesis, , # 5 p. 634 - 636

2280-28-6 24424-99-5 ~% 102507-13-1

文献：Tetrahedron Letters, , vol. 27, # 25 p. 2789 - 2792

2280-27-5 24424-99-5 ~% 102507-13-1

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 16 p. 4329 - 4332

上下游产品

上游产品  9
473545-40-3 288159-36-4 75-16-1 95715-85-8
2280-27-5 34619-03-9 108149-60-6 2280-28-6
24424-99-5
下游产品  2
2280-27-5 102507-19-7

海关

海关编码	2924199090
中文概述	2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%