267243-68-5

• 常用中文名：N4-(3-氯-4-氟苯基)-7-(3-吗啉丙氧基)喹唑啉-4,6-二胺
• 常用英文名：N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine
• CAS号：267243-68-5
• 分子式：C₂₁H₂₃ClFN₅O₂
• 分子量：431.89100
• 发布时间：2018-12-30 17:07:36
• 更新时间：2023-01-06 06:03:22

名称

• 中文名: N4-(3-氯-4-氟苯基)-7-(3-吗啉丙氧基)喹唑啉-4,6-二胺
• 英文名: 4-N-(3-chloro-4-fluorophenyl)-7-(3-morpholin-4-ylpropoxy)quinazoline-4,6-diamine
• 英文别名: 6-amino-4-[(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholino)propoxy]quinazoline; (3-chloro-4-fluorophenyl)-[7-(3-morpholino-4-yl-propoxy)-6-aminoquinazolin-4-yl]-amine; 6-amino-4-[N-(3-chloro-4-fluorophenyl)amino]-7-[3-(4-morpholinyl)propoxy]quinazoline; N*4*-(3-chloro-4-fluoro-phenyl)-7-(3-morpholin-4-yl-propoxy)-quinazoline-4,6-diamine; (3-CHLORO-4-FLUOROPHENYL)-[7-(3-MORPHOLIN-4-YL-PROPOXY)-6-AMINO-QUINAZOLINE-4-YL]-AMINE; N4-(3-chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazolin-4,6-diamine; N4-(3-Chloro-4-fluorophenyl)-7-(3-morpholinopropoxy)quinazoline-4,6-diamine

物化性质

• 分子式: C₂₁H₂₃ClFN₅O₂
• 分子量: 431.89100
• 精确质量: 431.15200
• PSA: 85.53000
• LogP: 4.44130
• 储存条件: 室温，干燥

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

合成路线

267243-64-1 ~98% 267243-68-5

文献：Warner-Lambert Company Patent: US6344455 B1, 2002 ; US 6344455 B1

367-21-5 98430-27-4 162012-70-6 ~78% 267243-68-5

文献：Warner-Lambert Company LLC Patent: US6664390 B2, 2003 ; Location in patent: Page column 8-9 ;

4441-30-9 367-21-5 865-47-4 162012-69-3 ~% 详细

文献：Barth, Hubert; Steiner, Klaus; Schneider, Simon Patent: US2003/50313 A1, 2003 ;

4441-30-9 ~% 267243-68-5

文献：Smaill, Jeff B.; Rewcastle, Gordon W.; Loo, Joseph A.; Greis, Kenneth D.; Chan, O. Helen; Reyner, Eric L.; Lipka, Elke; Showalter, H. D. Hollis; Vincent, Patrick W.; Elliott, William L.; Denny, William A. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1380 - 1397

367-21-5 ~% 267243-68-5

文献：Smaill, Jeff B.; Rewcastle, Gordon W.; Loo, Joseph A.; Greis, Kenneth D.; Chan, O. Helen; Reyner, Eric L.; Lipka, Elke; Showalter, H. D. Hollis; Vincent, Patrick W.; Elliott, William L.; Denny, William A. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1380 - 1397

162012-70-6 ~% 267243-68-5

文献：Smaill, Jeff B.; Rewcastle, Gordon W.; Loo, Joseph A.; Greis, Kenneth D.; Chan, O. Helen; Reyner, Eric L.; Lipka, Elke; Showalter, H. D. Hollis; Vincent, Patrick W.; Elliott, William L.; Denny, William A. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1380 - 1397

162012-67-1 ~% 267243-68-5

文献：Smaill, Jeff B.; Rewcastle, Gordon W.; Loo, Joseph A.; Greis, Kenneth D.; Chan, O. Helen; Reyner, Eric L.; Lipka, Elke; Showalter, H. D. Hollis; Vincent, Patrick W.; Elliott, William L.; Denny, William A. Journal of Medicinal Chemistry, 2000 , vol. 43, # 7 p. 1380 - 1397

上下游产品

上游产品  7
267243-64-1 367-21-5 162012-70-6 4441-30-9
865-47-4 162012-69-3 162012-67-1
下游产品  1
267243-64-1

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%