上海吉至生化科技有限公司
上海市上海市奉贤区
产品名：二溴氯丙烷
纯度：98.0%
规格：5g/25g
联系人：刘佳
联系电话：18116092098

上海创赛科技有限公司
上海市上海市嘉定区
产品名：[Perfemiker]二溴氯丙烷,98%
纯度：98.0%
规格：5g/25g/100g
联系人：夏言
联系电话：18016376636

上海阿拉丁生化科技股份有限公司
上海市上海市浦东新区
产品名：1,2-二溴-3-氯丙烷
纯度：97.0%
规格：25g/5g/1g/25g
联系人：阿拉丁李高志
联系电话：400-620-6333

查看所有供应商和价格请点击：

96-12-8生产厂家

96-12-8价格

96-12-8

96-12-8结构式

常用中文名：1,2-二溴-3-氯丙烷
常用英文名：dbcp
CAS号：96-12-8
分子式：C₃H₅Br₂Cl
分子量：236.33300
相关类别：无机化工无机盐金属卤化物及卤酸盐金属氟化物及盐
发布时间：2018-04-20 08:00:00
更新时间：2024-01-04 16:00:54
主要用作溶剂、土壤熏蒸剂、杀线虫剂。

化源商城直购

中文名	二溴氯丙烷
英文名	dbcp
中文别名	1,2-二溴-3-氯丙烷
英文别名	1,2-dibromo-3-chloro-propane dibromochloropropane 1,2-propylene glycol divinyl ether 1,2-Dibromo-3-chloropropane (RS)-1,2-dibromo-3-chloropropane MFCD00039365 4-methyl-3,6-dioxaocta-1,7-diene EINECS 202-479-3 1,2-bromochloropropane rac-(2R)-1,2-dibromo-3-chloropropane 1,2-bis-vinyloxy-propane

密度	2.05
沸点	195°C
熔点	6°C
分子式	C₃H₅Br₂Cl
分子量	236.33300
闪点	77 °C
精确质量	233.84500
LogP	2.38360
外观性状	一种无色液体
折射率	n/D 1.5542
储存条件	储存于阴凉、通风的库房。远离火种、热源。应与氧化剂、食用化学品分开存放，切忌混储。配备相应品种和数量的消防器材。储区应备有泄漏应急处理设备和合适的收容材料。
稳定性	避免与强氧化剂接触。
水溶解性	0.123 g/100 mL
分子结构	1、摩尔折射率：36.21 2、摩尔体积（cm³/mol）：116.1 3、等张比容（90.2K）：291.6 4、表面张力（dyne/cm）：39.6 5、介电常数： 6、偶极距（10^-24cm³）： 7、极化率：14.35
计算化学	1、疏水参数计算参考值（XlogP）：2.4 2、氢键供体数量：0 3、氢键受体数量：0 4、可旋转化学键数量：2 5、互变异构体数量： 6、拓扑分子极性表面积（TPSA）：0 7、重原子数量：6 8、表面电荷：0 9、复杂度：32 10、同位素原子数量：0 11、确定原子立构中心数量：0 12、不确定原子立构中心数量：1 13、确定化学键立构中心数量：0 14、不确定化学键立构中心数量：0 15、共价键单元数量：1
更多	1. 性状：浅黄色液体，有刺激性臭味。 2. 相对密度（g/mL,20/4℃）：2.081 3. 相对蒸汽密度（g/mL,空气=1）：8.2 4. 熔点（ºC）：6 5. 沸点（ºC,常压）：200 6. 沸点（ºC,1.33KPa）：196 7. 折射率（25ºC）：1.553 8. 闪点（ºC）：77 9. 饱和蒸气压（kPa, 21ºC）：0.12 10. 溶解性：微溶于水，溶于乙醇、丙酮、烃类等。与油类、二氯丙烷、异丙醇混溶。

第一部分：化学品名称

化学品中文名称：	1，2-二溴-3-氯丙烷；二溴氯丙烷
化学品英文名称：	1，2-Dibromo-3-chloropropane；1-Chloro-2，3-dibromopropane
中文俗名或商品名：
Synonyms：
CAS No.：	96-12-8
分子式：	C₃H₅Br₂Cl
分子量：	236.33

第二部分：成分/组成信息

纯化学品混合物

化学品名称：1，2-二溴-3-氯丙烷；二溴氯丙烷

有害物成分

含量

CAS No.

第三部分：危险性概述

危险性类别：	第6．1类毒害品
侵入途径：	吸入食入经皮吸收
健康危害：	经呼吸道和皮肤吸收。主要损伤中枢神经系统、睾丸、肝脏和肾脏。急性中毒主要症状有头晕、乏力、四肢麻木、腹痛、恶心、呕吐、肝区压痛、昏迷等，严重者出现肝、肾功能衰竭及休克而死亡。长期接触可造成男子不育症。
环境危害：	对环境有危害，对水体和大气可造成污染，对大气臭氧层有极强破坏力。
燃爆危险：	本品可燃，有毒。

第四部分：急救措施

皮肤接触：	脱去污染的衣着，用大量流动清水彻底冲洗。
眼睛接触：	立即翻开上下眼睑，用流动清水或生理盐水冲洗。
吸入：	迅速脱离现场至空气新鲜处。保持呼吸道通畅。呼吸困难时给输氧。呼吸停止时，立即进行人工呼吸。就医。
食入：	误服者漱口，饮足量温水，催吐，就医。

第五部分：消防措施

危险特性：	遇高热、明火或与氧化剂接触，有引起燃烧的危险。
有害燃烧产物：	氯化氢、溴化氢。
灭火方法及灭火剂：	消防人员须佩戴防毒面具、穿全身消防服，在上风向灭火。尽可能将容器从火场移至空旷处。喷水保持火场容器冷却，直至灭火结束。处在火场中的容器若已变色或从安全泄压装置中产生声音，必须马上撤离。灭火剂：雾状水、泡沫、干粉、二氧化碳、砂土。
消防员的个体防护：
禁止使用的灭火剂：
闪点(℃)：	77
自燃温度(℃)：	无资料
爆炸下限[%(V/V)]：	无资料
爆炸上限[%(V/V)]：	无资料
最小点火能(mJ)：
爆燃点：
爆速：
最大燃爆压力(MPa)：
建规火险分级：

第六部分：泄漏应急处理

应急处理：

迅速撤离泄漏污染区人员至安全区，并进行隔离，严格限制出入。切断火源。建议应急处理人员戴自给正压式呼吸器，穿防毒服。尽可能切断泄漏源。防止流入下水道、排洪沟等限制性空间。小量泄漏：用干燥的砂土或类似物质吸收。大量泄漏：构筑围堤或挖坑收容。用泵转移至槽车或专用收集器内，回收或运至废物处理场所处置。

第七部分：操作处置与储存

操作注意事项：

密闭操作，全面通风。操作人员必须经过专门培训，严格遵守操作规程。建议操作人员佩戴过滤式防毒面具（半面罩），戴化学安全防护眼镜，穿防毒物渗透工作服，戴橡胶耐油手套。远离火种、热源，工作场所严禁吸烟。使用防爆型的通风系统和设备。防止蒸气泄漏到工作场所空气中。避免与氧化剂接触。搬运时要轻装轻卸，防止包装及容器损坏。配备相应品种和数量的消防器材及泄漏应急处理设备。倒空的容器可能残留有害物。

储存注意事项：

储存于阴凉、通风的库房。远离火种、热源。应与氧化剂、食用化学品分开存放，切忌混储。配备相应品种和数量的消防器材。储区应备有泄漏应急处理设备和合适的收容材料。

第八部分：接触控制/个体防护

最高容许浓度：	中国 MAC：未制订标准前苏联MAC：未制订标准美国TLV—TWA：未制订标准美国
监测方法：
工程控制：	生产过程密闭，全面通风。
呼吸系统防护：	可能接触其蒸气时，应该佩戴防毒面具。
眼睛防护：	戴化学安全防护眼镜。
身体防护：	穿化学防护服。
手防护：	必要时戴防化学品手套。
其他防护：	工作现场禁止吸烟、进食和饮水。工作后，淋浴更衣。单独存放被毒物污染的衣服，洗后再用。

第九部分：理化特性

外观与性状：	琥珀色至棕色液体，有刺鼻气味。
pH：
熔点(℃)：	6.7
沸点(℃)：	196
相对密度(水=1)：	2.08
相对蒸气密度(空气=1)：	8.2
饱和蒸气压(kPa)：	0.12(21℃)
燃烧热(kJ/mol)：
临界温度(℃)：
临界压力(MPa)：
辛醇/水分配系数的对数值：
闪点(℃)：	77
引燃温度(℃)：	无资料
爆炸上限%(V/V)：	无资料
爆炸下限%(V/V)：	无资料
分子式：	C₃H₅Br₂Cl
分子量：	236.33
蒸发速率：
粘性：
溶解性：	微溶于水，溶于乙醇、丙酮、烃类等。
主要用途：	主要用作植物土壤薰蒸剂。

第十部分：稳定性和反应活性

稳定性：	在常温常压下稳定
禁配物：	强氧化剂。
避免接触的条件：
聚合危害：	不能出现
分解产物：	氯化氢、溴化氢。

第十一部分：毒理学资料

急性毒性：	LD50：170mg／kg(大鼠经口)；260mg／kg(小鼠经口) LC50：154ppm 4小时(大鼠吸入)
急性中毒：
慢性中毒：
亚急性和慢性毒性：
刺激性：	家兔经皮：10 g重度刺激。家兔经眼：1%轻度刺激。
致敏性：
致突变性：
致畸性：
致癌性：

第十二部分：生态学资料

生态毒理毒性：
生物降解性：
非生物降解性：
生物富集或生物积累性：

第十三部分：废弃处置

废弃物性质：
废弃处置方法：	根据国家和地方有关法规的要求处置。或与厂商或制造商联系，确定处置方法。
废弃注意事项：

第十四部分：运输信息

危险货物编号：
UN编号：	2872
包装标志：
包装类别：	Ⅲ
包装方法：
运输注意事项：	运输前应先检查包装容器是否完整、密封，运输过程中要确保容器不泄漏、不倒塌、不坠落、不损坏。严禁与氧化剂、食用化学品等混装混运。运输车船必须彻底清洗、消毒，否则不得装运其它物品。船运时，配装位置应远离卧室、厨房，并与机舱、电源、火源等部位隔离。公路运输时要按规定路线行驶。
RETCS号：
IMDG规则页码：

第十五部分：法规信息

国内化学品安全管理法规：	化学危险物品安全管理条例 (1987年2月17日国务院发布)，化学危险物品安全管理条例实施细则 (化劳发[1992] 677号)，工作场所安全使用化学品规定 ([1996]劳部发423号)等法规，针对化学危险品的安全使用、生产、储存、运输、装卸等方面均作了相应规定。
国际化学品安全管理法规：

第十六部分：其他信息

参考文献：	1.周国泰，化学危险品安全技术全书，化学工业出版社，1997 2.国家环保局有毒化学品管理办公室、北京化工研究院合编，化学品毒性法规环境数据手册，中国环境科学出版社.1992 3.Canadian Centre for Occupational Health and Safety,CHEMINFO Database.1998 4.Canadian Centre for Occupational Health and Safety, RTECS Database, 1989
填表时间：	年月日
填表部门：
数据审核单位：
修改说明：
其他信息：	3
MSDS修改日期：	年月日

毒理学数据:

1、刺激性：家兔经皮：10 g重度刺激。家兔经眼：1%轻度刺激。

2、急性毒性：大鼠经口LD5O：170mg/kg

小鼠经口LD5O：260mg/kg

大鼠吸入LC50：154ppm，4小时 3、对人体有害。毒性较强，对老鼠经口试验发现有致癌作用。

生态学数据:

该物质对环境有危害，应特别注意对水体和空气的污染，对大气臭氧层有极强破坏力。

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TX8750000

CHEMICAL NAME :: Propane, 1,2-dibromo-3-chloro-

CAS REGISTRY NUMBER :: 96-12-8

BEILSTEIN REFERENCE NO. :: 1732077

LAST UPDATED :: 199801

DATA ITEMS CITED :: 112

MOLECULAR FORMULA :: C3-H5-Br2-Cl

MOLECULAR WEIGHT :: 236.35

WISWESSER LINE NOTATION :: G1YE1E

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 170 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 103 ppm/8H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 257 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 123 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 180 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - chicken

DOSE/DURATION :: 60 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3150 mg/kg/45D-I

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), diffuse Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring) Blood - changes in spleen

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2025 mg/kg/90D-C

TOXIC EFFECTS :: Liver - changes in liver weight Kidney, Ureter, Bladder - changes in bladder weight Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 602 mg/kg/64D-C

TOXIC EFFECTS :: Behavioral - fluid intake Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - changes in testicular weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 ppm/7H/70D-I

TOXIC EFFECTS :: Liver - changes in liver weight Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - changes in testicular weight

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 25 ppm/6H/13W-I

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), zonal Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Blood - changes in bone marrow (not otherwise specified)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10 ppm/24H/14D-C

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 160 mg/kg/2D-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes Blood - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2400 mg/kg/12W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in leukocyte (WBC) count Related to Chronic Data - changes in testicular weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 11940 mg/kg/6W-I

TOXIC EFFECTS :: Related to Chronic Data - death

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5 ppm/6H/13W-I

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Related to Chronic Data - death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 12 ppm/7H/70D-I

TOXIC EFFECTS :: Related to Chronic Data - changes in testicular weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 12 ppm/7H/70D-I

TOXIC EFFECTS :: Related to Chronic Data - changes in testicular weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5475 mg/kg/73W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 600 ppb/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 240 mg/kg/12W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 49 gm/kg/47W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 ppb/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 100 gm/kg/74W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 9280 mg/kg/64W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 ppm/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 600 ppb/6H/76W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Endocrine - adrenal cortex tumors

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 ppm/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 ppb/6H/76W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 600 ppb/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Endocrine - adrenal cortex tumors

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3 ppm/6H/84W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Endocrine - adrenal cortex tumors

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 ppb/6H/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 ppm/6H/76W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 240 mg/kg/12W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 200 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - other effects on male

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 500 mg/kg

SEX/DURATION :: female 6-15 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 250 mg/kg

SEX/DURATION :: male 5 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 50 mg/kg

SEX/DURATION :: male 5 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetal death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 375 mg/kg

SEX/DURATION :: male 75 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 10 ppm/6H

SEX/DURATION :: male 4 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 1 ppm/6H

SEX/DURATION :: male 4 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 20090 ug/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male Reproductive - Specific Developmental Abnormalities - urogenital system

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 50 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 33 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 19 mg/kg

SEX/DURATION :: male 19 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

DOSE :: 40 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

DOSE :: 100 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 92657 ug/kg

SEX/DURATION :: male 10 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 1 ppm/6H

SEX/DURATION :: male 70 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

DOSE :: 10 ppm/6H

SEX/DURATION :: male 40 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - male fertility index (e.g. # males impregnating females per # males exposed to fertile nonpregnant females)

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Heritable translocation test

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: DNA damage

TYPE OF TEST :: DNA damage

TYPE OF TEST :: Unscheduled DNA synthesis

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Dominant lethal test

TYPE OF TEST :: Sperm Morphology

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: Unscheduled DNA synthesis

MUTATION DATA

TEST SYSTEM :: Rodent - rabbit

REFERENCE :: FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 6,628,1986 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 20,83,1979 IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,139,1977 IARC Cancer Review:Human Inadequate Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,191,1987 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,191,1987 TOXICOLOGY REVIEW LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823- Volume(issue)/page/year: 2,1259,1977 TOXICOLOGY REVIEW FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 13,747,1989 *** U.S. STANDARDS AND REGULATIONS *** OSHA PEL (Construc):see CFR 29,1926.1144 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA-cancer hazard CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1044,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-DENMARK:TWA 0.001 ppm (0.01 mg/m3);Carcinogen JAN 1993 OEL-FINLAND;Carcinogen JAN 1993 OEL-FRANCE;Carcinogen JAN 1993 OEL-GERMANY;Carcinogen JAN 1993 OEL-SWEDEN;Carcinogen JAN 1993 OEL-SWITZERLAND;Carcinogen JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO 1,2-DIBROMO-3-CHLOROPROPANE-air:CA use 29 CFR 1910.1044 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2705 No. of Facilities: 8 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 176 (estimated)

符号	GHS02, GHS06, GHS08
信号词	Danger
危害声明	H225-H301 + H311 + H331-H340-H350-H360F-H370
警示性声明	P201-P210-P260-P280-P301 + P310 + P330-P308 + P311-P403 + P233
个人防护装备	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
危害码 (欧洲)	T:Toxic;
风险声明 (欧洲)	R45;R46;R60;R25;R48/20/22;R52/53
安全声明 (欧洲)	S53-S45-S61-S36/37-S16-S7
危险品运输编码	2872
RTECS号	TX8750000
包装等级	III
危险类别	6.1(b)
海关编码	2903799010

107-05-1

~6%

96-12-8

37161-81-2

32753-90-5

详细

文献：Journal of Organic Chemistry USSR (English Translation), , vol. 23, p. 230 - 236 Zhurnal Organicheskoi Khimii, , vol. 23, # 2 p. 262 - 269

107-05-1

96-12-8

文献：Bulletin of the Chemical Society of Japan, , vol. 47, p. 143 - 146

3712-44-5

96-12-8

3492-46-4

文献：Russian Journal of General Chemistry, , vol. 66, # 1 p. 66 - 71

106-89-8

96-12-8

3492-46-4

文献：Russian Journal of General Chemistry, , vol. 66, # 1 p. 66 - 71

106-89-8

96-12-8

文献：Justus Liebigs Annalen der Chemie, , vol. 152, p. 320

上游产品 3
107-05-1 3712-44-5 106-89-8
下游产品 9
16400-63-8 85576-83-6 513-31-5 56-81-5
32753-90-5 32753-89-2 816-38-6 50-00-0
71-52-3

海关编码	2903799010
中文概述	2903799010 二溴氯丙烷〔1,2-二溴-3-氯丙烷〕。监管条件:89(禁止出口商品,禁止进口商品)。增值税率:17.0%。退税率:9.0%。最低关税:5.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
监管条件	8.禁止出口商品 9.禁止进口商品
Summary	2903799010 1,2-dibromo-3-chloropropane。supervision conditions:89(articles on the list of prohibited export goods,articles on the list of prohibited import goods)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:5.5%。general tariff:30.0%

96-12-8	453-00-9
32595-09-8	70289-31-5
104514-49-0	35691-65-7
51209-47-3	78-75-1
78-87-5	93952-08-0