59831-94-6

• 常用中文名：阿魏酸异丙酯
• 常用英文名：Isopropyl ferulate
• CAS号：59831-94-6
• 分子式：C₁₃H₁₆O₄
• 分子量：236.26400
• 相关类别： 研究领域 感染
• 发布时间：2018-08-31 23:55:58
• 更新时间：2026-07-01 20:45:16
• Isopropyl ferulate 是 Rhizoma et Radix (羌活)的提取物,可用于药物还原、抗真菌剂的制备,化妆品以及氧化剂等。

名称

• 中文名: 阿魏酸异丙酯
• 英文名: propan-2-yl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
• 中文别名: 4-羟基-3-甲氧基肉桂酸异丙酯; Isopropyl ferulate #天然产物 HY-N4203
• 英文别名: CINNAMIC ACID,4-HYDROXY-3-METHOXY-,ISOPROPYL ESTER; PROPAN-2-YL (E)-3-(4-HYDROXY-3-METHOXY-PHENYL)PROP-2-ENOATE; trans-Isopropyl; Ferulic Acid Impurity 4; 4-Hydroxy-3-methoxycinnamic acid isopropyl ester; TRANS-ISOPROPYL FERULATE; 3-(4-Hydroxy-3-methoxyphenyl)-2-propenoic acid 1-methylethyl ester; Isopropyl 3-(4-hydroxy-3-Methoxyphenyl)acrylate; 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, 1-methylethyl ester; Trans-isopropyl ferulate; iso-proylFerulic acid

物化性质

• 密度: 1.145g/cm3
• 沸点: 358.2ºC at 760mmHg
• 分子式: C₁₃H₁₆O₄
• 分子量: 236.26400
• 闪点: 131.9ºC
• 精确质量: 236.10500
• PSA: 55.76000
• LogP: 2.36560
• 折射率: 1.556

生物活性

• 描述: Isopropyl ferulate 是 Rhizoma et Radix (羌活)的提取物,可用于药物还原、抗真菌剂的制备,化妆品以及氧化剂等。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Kumar A, et al. Synthesis of isopropyl ferulate using silica-immobilized lipase in an organic medium. Enzyme Res. 2011;2011:718949.

  [2]. Li F, et al. Anti-austerity agents from Rhizoma et Radix Notopterygii (Qianghuo). Planta Med. 2012 May;78(8):796-9.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GD9450000 CHEMICAL NAME : Cinnamic acid, 4-hydroxy-3-methoxy-, isopropyl ester CAS REGISTRY NUMBER : 59831-94-6 LAST UPDATED : 199309 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C13-H16-O4 MOLECULAR WEIGHT : 236.29 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1059 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 25,187,1987

安全

• 海关编码: 2918990090

合成路线

56766-77-9 121-33-5 ~72% 59831-94-6

文献：Wang, Huan; Wei, Qing-Yi; Jiang, Hong; Jiang, Zhen-Hua Research on Chemical Intermediates, 2012 , vol. 38, # 1 p. 207 - 213

1135-24-6 67-63-0 ~66% 59831-94-6

文献：Li, Weixia; Li, Nianguang; Tang, Yuping; Li, Baoquan; Liu, Li; Zhang, Xu; Fu, Haian; Duan, Jin-Ao Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 19 p. 6085 - 6088

海关

海关编码	2918990090
中文概述	2918990090. 其他含其他附加含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%