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19895-95-5生产厂家

19895-95-5价格

19895-95-5

19895-95-5结构式
19895-95-5结构式

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中文名 山奈酚-3-O-β-D-槐糖苷
英文名 kaempferol 3-O-β-D-glucosyl-(1→2)-β-D-glucoside
中文别名 山奈酚-3-O-Beta-D-槐糖苷
山奈酚-3-O-Beta-D-槐糖苷,山奈酚-3-O-槐糖苷
英文别名 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
Kaempferol-3-sophoroside
4H-1-Benzopyran-4-one, 3-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-5,7-dihydroxy-2-(4-hydroxyphenyl)-
Kaempferol 3-O-sophoroside
Sophoraflavonoloside
K3S
3-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-5,7-dihydroxy-2-(4-hydroxyphenyl)chromen-4-one
kaempferol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside
描述 Kaempferol 3-O-sophoroside,Kaempferol 的衍生物,分离于栽培山参 (Panax ginseng) 的叶子,具有抗炎活性。
相关类别
靶点

Kaempferol 3-O-sophoroside possesses barrier integrity activity, inhibitory activity on cell adhesion and migration to endothelial cells by blocking the activation of NF-κB expression and production of TNF-α, thereby endorsing its usefulness as therapy for vascular inflammatory diseases[1].

参考文献

[1]. Kim TH, et al. Anti-inflammatory effects of kaempferol-3-O-sophoroside in human endothelial cells. Inflamm Res. 2012 Mar;61(3):217-24.

密度 1.8±0.1 g/cm3
沸点 995.0±65.0 °C at 760 mmHg
熔点 194-198℃
分子式 C27H30O16
分子量 610.518
闪点 329.3±27.8 °C
精确质量 610.153381
PSA 269.43000
LogP -0.58
外观性状 粉末
蒸汽压 0.0±0.3 mmHg at 25°C
折射率 1.764
储存条件 室温,惰性气体

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DJ3068000
CHEMICAL NAME :
4H-1-Benzopyran-4-one, 3-((2-O-beta-D-glucopyranosyl-beta-diglucopyranosyl)o xy)-5,7- dihydroxy-2-(4-hydroxyphenyl)-
CAS REGISTRY NUMBER :
19895-95-5
LAST UPDATED :
199206
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C27-H30-O16
MOLECULAR WEIGHT :
610.57

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JOETD7 Journal of Ethnopharmacology. (Elsevier Scientific Pub. Ireland Ltd., POB 85, Limerick, Ireland) V.1- 1979- Volume(issue)/page/year: 29,73,1990

危害码 (欧洲) Xi

~49%

19895-95-5结构式

19895-95-5

文献:Markham, Kenneth R.; Andersen, Oeyvind M. Phytochemistry (Elsevier), 1990 , vol. 29, # 12 p. 3919 - 3920

~%

19895-95-5结构式

19895-95-5

文献:Yoshida; Saito; Kadoya Chemical and Pharmaceutical Bulletin, 1987 , vol. 35, # 1 p. 97 - 107

~%

19895-95-5结构式

19895-95-5

文献:Chemical and Pharmaceutical Bulletin, , vol. 35, # 1 p. 97 - 107
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