60547-97-9

• 常用中文名：2-(1-哌嗪基)-4-氨基-6,7-二甲氧基喹唑啉
• 常用英文名：2-PIPERAZINE-4- AMINO-6,7 DIMETHOXYQUINAZOLINE
• CAS号：60547-97-9
• 分子式：C₁₄H₁₉N₅O₂
• 分子量：289.33300
• 发布时间：2018-10-20 13:16:56
• 更新时间：2026-07-14 17:15:55

名称

• 中文名: 2-哌嗪基-4-氨基-6,7-二甲氧基喹唑啉
• 英文名: 2-Piperazinyl-4-amino-6,7-dimethoxyquinazoline
• 中文别名: 盐酸特拉唑嗪杂质Ⅰ(1-(4-氨基-6,7-二甲氧基-2-喹唑啉基)哌嗪二盐酸盐); 特拉唑嗪杂质2(特拉唑嗪杂质C); 特拉唑嗪标准品004; 特拉唑嗪杂质C(甲磺酸多沙唑嗪杂质G)(PRAZOSIN 杂质C); 特拉唑嗪杂质C(多沙唑嗪杂质G,哌唑嗪杂质C); 特拉唑嗪相关化合物A; 哌唑嗪杂质C; 甲磺酸多沙唑嗪杂质G; 特拉唑嗪杂质C; 盐酸特拉唑嗪杂质Ⅰ(1-（4-氨基-6，7-二甲氧基-2-喹唑啉基）哌嗪二盐酸盐); 盐酸哌唑嗪杂质C; 4-氨基-2-(1-哌嗪基)-6,7-二甲氧基喹唑啉; 2-哌嗪-4-氨基-6,7-二氧基喹唑啉盐酸盐; 2-哌嗪基-4-氨基-6,7-二甲氧基喹; 盐酸特拉唑嗪杂质C; 特拉唑嗪杂质7; 甲磺酸多沙唑嗪杂质G/盐酸哌唑嗪杂质C/盐酸特拉唑嗪杂质C 标准品; 多沙唑嗪杂质7(多沙唑嗪杂质G); 多沙唑嗪杂质G
• 英文别名: Terazosin Impurity 2(Terazosin Impurity C); 6,7-Dimethoxy-2-(piperazin-1-yl)quinazolin-4-amine, 1-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazine; 2-Piperzaine-4-Amino-6,7-Dimet; Doxazosin Impurity 7（Doxazosin Impurity G）; 6,7-DIMETHOXY-2-PIPERAZINO-4-AMINOQUINAZOLINE; 2-Piperzaine-4-Amino-6,7-Dimethoxy Quinazoline; 6,7-Dimethoxy-2-(1-piperzinyl)-4-quinazolinamine; 6,7-DIMETHOXY-2-(1-PIPERAZINYL)-4-QUINAZOLINAMINE; Doxazosin Mesilate Impurity G; Terazosin-004; 2-piperazine-4-amino-6,7-dimethoxyquinazoline; 2-PIPERAZINYL-6,7-DIMETHOXYQUINAZOLIN-4-AMINE; Doxazosin Impurity G; 6,7-DIMETHOXY-2-(PIPERAZIN-1-YL)QUINAZOLIN-4-AMINE; 4-QUINAZOLINAMINE, 6,7-DIMETHOXY-2-(1-PIPERAZINYL); Terazosin Impurity C RC A); MFCD00563872; Doxazocin impurity G; 6,7-Dimethoxy-2-piperazino-4-quinazolinylamine; 2-PIPERAZINE - 4- AMINO - 6,7 DIMETHOXYQUINAZOLINE; 7-diMethoxyquinazoline HCl; 2-(1-PIPERAZINYL)-4-AMINO-6,7-DIMETHOXYQUINAZOLINE; Terazosin Hydrochloride Impurity Ⅰ：1-(4-amino-6,7-dimethoxy-2-quinazolinyl) piperazine dihydrochloride; Prazosin Hydrochloride Impurity C; Terazosin IMpurity C; Terazosin Hydrochloride Dihydrate Impurity C; Prazosin Impurity 3(Prazosin Impurity C); 6,7-DIMETHOXY-2-PIPERAZIN-1-YL-QUINAZOLIN-4-YLAMINE; Terazosin Impurity C (Doxazosin Mesylate Impurity G) (Prazosin Impurity C); Terazosin Related Compound A; 4-Amino-2-(1-piperazinyl)-6,7-dimethoxyquinazoline; 6,7-Dimethoxy-2-(piperazin-1-yl)qui; 6,7-dimethoxy-N-(1-piperazinyl)-2-quinazolinamine; Terazosin IMP C; 6,7-dimethoxy-N-(piperazin-1-yl)quinazolin-2-amine; Terazosin Impurity C (Doxazosin Impurity G, Prazosin Impurity C); Terazosin Impurity7; 2-(1-Piperazinyl)-4-amino-6; 6,7-dimethoxy-2-piperazin-1-ylquinazolin-4-amine; 2-(1-Piperazinyl)-4-amino-6,7-dimethoxyquinazoline HCl; Prazosin Impurity C; 6,7-Dimethoxy-2(1-Piperazinyl)-Quinozoline

物化性质

• 密度: 1.265 g/cm3
• 沸点: 527ºC at 760 mmHg
• 熔点: 219-221ºC (dec.)
• 分子式: C₁₄H₁₉N₅O₂
• 分子量: 289.33300
• 闪点: 272.5ºC
• 精确质量: 289.15400
• PSA: 85.53000
• LogP: 1.61380
• 外观性状: 白色粉末
• 折射率: 1.63
• 储存条件: Refrigerator

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933499090

合成路线

766532-56-3 ~% 60547-97-9

文献：Journal of medicinal chemistry, , vol. 47, # 18 p. 4453 - 4462

110-85-0 23680-84-4 ~78% 60547-97-9

文献：Cavalli, Andrea; Lizzi, Federica; Bongarzone, Salvatore; Brun, Reto; Luise Krauth-Siegel; Bolognesi, Maria Laura Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 11 p. 3031 - 3035

23680-84-4 ~% 60547-97-9

文献：Tetrahedron Letters, , vol. 47, # 15 p. 2549 - 2552

上下游产品

上游产品  2
110-85-0 23680-84-4
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107021-36-3 74191-85-8 19237-84-4 19216-56-9
79221-43-5

海关

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%