2706-50-5

• 常用中文名：DL-安非他明 盐酸盐
• 常用英文名：rac AMphetaMine Hydrochloride
• CAS号：2706-50-5
• 分子式：C₉H₁₄ClN
• 分子量：171.66700
• 相关类别： 分析化学 标准品 法医和兽医标准品
• 发布时间：2017-12-30 06:56:14
• 更新时间：2024-01-08 17:00:05
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名称

• 中文名: DL-安非他明 盐酸盐
• 英文名: 1-Phenyl-2-propanamine hydrochloride (1:1)
• 英文别名: 1-methyl-2-phenylethylammonium chloride; 1-phenyl-2-propylamine hydrochloride; (+/-)-Amphetamine hydrochloride; Amphetaminhydrochlorid; phenamine hydrochloride; 1-Phenyl-2-propyl methanesulfonate; 1-methyl-2-phenylethyl methanesulfonate; 1-methyl-2-phenyl-ethylamine hydrochloride; 1-phenyl-2-propanol mesylate

物化性质

• 沸点: 201.5ºC at 760mmHg
• 熔点: 127-129?C
• 分子式: C₉H₁₄ClN
• 分子量: 171.66700
• 闪点: 87.4ºC
• 精确质量: 171.08100
• PSA: 26.02000
• LogP: 3.07860
• 储存条件: Controlled Substance, -20?C Freezer, Under Inert Atmosphere

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SH9798450 CHEMICAL NAME : Phenethylamine, alpha-methyl-, hydrochloride, (+-)- CAS REGISTRY NUMBER : 2706-50-5 LAST UPDATED : 198806 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C9-H13-N.Cl-H MOLECULAR WEIGHT : 171.69 WISWESSER LINE NOTATION : ZY1&1R &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 45 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JACSAT Journal of the American Chemical Society. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1879- Volume(issue)/page/year: 64,533,1942 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 40 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Vascular - BP elevation not characterized in autonomic section REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 8,100,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 15 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 79,187,1943 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 52 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 47,339,1933

安全

• 符号: GHS06
• 信号词: Danger
• 危害声明: H300
• 警示性声明: P264-P301 + P310
• 个人防护装备: Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
• 危害码 (欧洲): T
• 风险声明 (欧洲): 25
• 安全声明 (欧洲): 45
• 危险品运输编码: UN 2811 6.1 / PGII
• RTECS号: SH9798450
• 海关编码: 2921499090

合成路线

39861-30-8 ~73% 2706-50-5

文献：BOEHRINGER INGELHEIM CHEMICALS INC Patent: JP2005/507936 A, 2005 ; Location in patent: Page/Page column 13-14 ;

7761-64-0 ~62% 2706-50-5

文献：Koziara, Anna; Olejniczak, Bogdan; Osowska, Krystyna; Zwierzak, Andrzej Synthesis, 1982 , # 11 p. 918 - 920

345308-53-4 ~73% 2706-50-5

文献：Krzyzanowska, B.; Stec, W. J. Synthesis, 1982 , # 4 p. 270 - 273

31731-87-0 ~% 2706-50-5

文献：Kitamura, Mitsuru; Suga, Takahiro; Chiba, Shunsuke; Narasaka, Koichi Organic Letters, 2004 , vol. 6, # 24 p. 4619 - 4621

3198-15-0 ~39% 2706-50-5

文献：BOEHRINGER INGELHEIM CHEMICALS INC Patent: JP2005/507936 A, 2005 ; Location in patent: Page/Page column 13 ;

300-57-2 ~% 2706-50-5

文献：Koziara, Anna; Olejniczak, Bogdan; Osowska, Krystyna; Zwierzak, Andrzej Synthesis, 1982 , # 11 p. 918 - 920

82572-07-4 ~% 2706-50-5

文献：Krzyzanowska, B.; Stec, W. J. Synthesis, 1982 , # 4 p. 270 - 273

13213-36-0 ~% 2706-50-5

文献：Krzyzanowska, B.; Stec, W. J. Synthesis, 1982 , # 4 p. 270 - 273

上下游产品

上游产品  8
39861-30-8 7761-64-0 345308-53-4 31731-87-0
3198-15-0 300-57-2 82572-07-4 13213-36-0
下游产品  2
33061-37-9 17590-01-1

海关

海关编码	2921499090
中文概述	2921499090 其他芳香单胺及衍生物及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%