121-24-4
121-24-4结构式
| 中文名 | 氧化型谷胱甘肽 |
|---|---|
| 英文名 | 2-amino-5-[[3-[[2-[(4-amino-4-carboxybutanoyl)amino]-3-(carboxymethylamino)-3-oxopropyl]disulfanyl]-1-(carboxymethylamino)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid |
| 英文别名 |
glutathione oxidized
GSSG,glutathione oxidized EINECS 248-170-7 |
| 熔点 | 178ºC (dec.)(lit.) |
|---|---|
| 分子式 | C20H34N6O13S2 |
| 分子量 | 630.646 |
| 精确质量 | 630.162537 |
| PSA | 368.24000 |
| 储存条件 | 2-8°C |
| 分子结构 | 1、 摩尔折射率：138.36 2、 摩尔体积（cm3/mol）：397.7 3、 等张比容（90.2K）：1196.0 4、 表面张力（dyne/cm）：81.7 5、 极化率（10-24cm3）：54.85 |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:-9.1 2.氢键供体数量:10 3.氢键受体数量:16 4.可旋转化学键数量:21 5.互变异构体数量:10 6.拓扑分子极性表面积368 7.重原子数量:40 8.表面电荷:0 9.复杂度:879 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:4 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1 |
Synonym:None known Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
Appearance: almost white. Caution! The toxicological properties of this material have not been fully investigated. May cause eye and skin irritation. May cause respiratory and digestive tract irritation. Target Organs: No data found. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits +--------------------+-------------------+-------------------+-----------------+ | Chemical Name | ACGIH | NIOSH |OSHA - Final PELs| |--------------------|-------------------|-------------------|-----------------| | (-)-Glutathione, Hy|none listed |none listed |none listed | | drate, Oxidized (GS| | | | | SG) | | | | +--------------------+-------------------+-------------------+-----------------+ OSHA Vacated PELs: (-)-Glutathione, Hydrate, Oxidized (GSSG): No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Appearance: almost white Odor: practically odorless pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 178-182C Autoignition Temperature: Not applicable. Flash Point: Not applicable. NFPA Rating: (est.) Health: 1; Flammability: 0; Reactivity: 0 Explosion Limits, Lower: Not available. Upper: Not available. Decomposition Temperature: > 182 deg C Solubility: Specific Gravity/Density: Molecular Formula: C20H32N6O12S2.xH2O Molecular Weight: 612.377 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, dust generation, excess heat. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, hydrogen sulfide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 121-24-4 unlisted. LD50/LC50: Not available. Carcinogenicity: (-)-Glutathione, Hydrate, Oxidized (GSSG) - Not listed by ACGIH, IARC, NIOSH, NTP, or OSHA. See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Chemical waste generators must determine whether a discarded chemical is classif as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Part Additionally, waste generators must consult state and local hazardous waste regu ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed. Section 14 - TRANSPORT INFORMATION CDG/CPL Not classified as hazardous for supply. Canadian TDG No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 121-24-4: No information available. United Kingdom Occupational Exposure Limits Canada None of the chemicals in this product are listed on the DSL/NDSL list. WHMIS: Not available. CAS# 121-24-4 is not listed on Canada's Ingredient Disclosure List. Exposure Limits US FEDERAL TSCA CAS# 121-24-4 is not listed on the TSCA inventory. It is for research and development use only. Health & Safety Reporting List None of the chemicals are on the Health & Safety Reporting List. Chemical Test Rules None of the chemicals in this product are under a Chemical Test Rule. Section 12b None of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use Rule None of the chemicals in this material have a SNUR under TSCA. SARA Section 302 (RQ) None of the chemicals in this material have an RQ. Section 302 (TPQ) None of the chemicals in this product have a TPQ. Section 313 No chemicals are reportable under Section 313. Clean Air Act: This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. SECTION 16 - ADDITIONAL INFORMATION N/A |