172695-22-6

• 常用中文名：(S)-(1-氰基丙烷-2-基)氨基甲酸叔丁酯
• 常用英文名：(S)-tert-Butyl (1-cyanopropan-2-yl)carbamate
• CAS号：172695-22-6
• 分子式：C₉H₁₆N₂O₂
• 分子量：184.23600
• 发布时间：2018-10-13 11:17:20
• 更新时间：2025-08-28 21:02:16

名称

• 中文名: 3-N-boc-(s)-氨基丁腈
• 英文名: 3-n-boc-(s)-amino butyronitrile
• 中文别名: 2-甲基-2-丙基[(2S)-1-氰基-2-丙基]氨基甲酸酯; [(2S)-1-氰基-2-丙基]氨基甲酸叔丁酯; (S)-(1-氰基丙-2-基)氨基甲酸叔丁酯; (S)-3-(BOC-氨基)丁腈
• 英文别名: 3-N-BOC-(S)-AMINO BUTYRONITRILE; tert-butyl N-[(1S)-2-cyano-1-methyl-ethyl]cbamate; (S)-3-{[(benzyloxy)carbonyl]amino}butanoic acid; (S)-3-(Boc-Amino)butanenitrile; (S)-tert-butyl 1-cyanopropan-2-ylcbaMate; tert-butyl (S)-(1-cyanopropan-2-yl) carbamate; Cbamic acid, [(1S)-2-cyano-1-methylethyl]-, 1,1-dimethylethyl ester (9CI); tert-butyl [(1S)-2-cyano-1-Methylethyl]cbaMate; Z-L-|A-Homoalanine; tert-butyl (S)-(1-cyanopropan-2-yl) cbamate; Cbamic acid, N-[(1S)-2-cyano-1-methylethyl]-, 1,1-dimethylethyl ester; Cbz-L-3-Aminobutyric acid; Z-|A-Homoala-OH

物化性质

• 密度: 1.005g/cm3
• 沸点: 309.5ºC at 760 mmHg
• 分子式: C₉H₁₆N₂O₂
• 分子量: 184.23600
• 闪点: 141ºC
• 精确质量: 184.12100
• PSA: 62.12000
• LogP: 2.20418
• 外观性状: 固体
• 蒸汽压: 0.000635mmHg at 25°C
• 折射率: 1.447
• 储存条件: 室温， 干燥

安全

• 危害码 (欧洲): Xn
• 海关编码: 2926909090

合成路线

126301-16-4 ~85% 172695-22-6

文献：MILLENNIUM PHARMACEUTICALS, INC. Patent: WO2005/100321 A1, 2005 ; Location in patent: Page/Page column 160-161 ; WO 2005/100321 A1

143-33-9 126301-16-4 ~73% 172695-22-6

文献：Lebreton, Luc; Jost, Eric; Carboni, Bertrand; Annat, Jocelyne; Vaultier, Michel; Dutartre, Patrick; Renaut, Patrice Journal of Medicinal Chemistry, 1999 , vol. 42, # 23 p. 4749 - 4763

79069-13-9 ~% 172695-22-6

文献：Caputo, Romualdo; Cassano, Ersilia; Longobardo, Luigi; Palumbo, Giovanni Tetrahedron, 1995 , vol. 51, # 45 p. 12337 - 12350

773837-37-9 126301-16-4 ~65% 172695-22-6

文献：Veitia, Maite Sylla-Iyarreta; Brun, Pierre Louis; Jorda, Pierre; Falguieres, Annie; Ferroud, Clotilde Tetrahedron Asymmetry, 2009 , vol. 20, # 18 p. 2077 - 2089

13435-20-6 161529-20-0 ~84% 172695-22-6

文献：Caputo, Romualdo; Cassano, Ersilia; Longobardo, Luigi; Palumbo, Giovanni Tetrahedron, 1995 , vol. 51, # 45 p. 12337 - 12350

24424-99-5 ~% 172695-22-6

文献：Caputo, Romualdo; Cassano, Ersilia; Longobardo, Luigi; Palumbo, Giovanni Tetrahedron, 1995 , vol. 51, # 45 p. 12337 - 12350

15761-38-3 ~% 172695-22-6

文献：Xin, Dongyue; Perez, Lisa M.; Ioerger, Thomas R.; Burgess, Kevin Angewandte Chemie - International Edition, 2014 , vol. 53, # 14 p. 3594 - 3598 Angew. Chem., 2014 , vol. 126, # 14 p. 3668 - 3672,5

109208-68-6 ~% 172695-22-6

文献：Xin, Dongyue; Perez, Lisa M.; Ioerger, Thomas R.; Burgess, Kevin Angewandte Chemie - International Edition, 2014 , vol. 53, # 14 p. 3594 - 3598 Angew. Chem., 2014 , vol. 126, # 14 p. 3668 - 3672,5

143-33-9 84765-24-2 ~% 172695-22-6

文献：Sutherland, Andrew; Willis, Christine L. Journal of Organic Chemistry, 1998 , vol. 63, # 22 p. 7764 - 7769

上下游产品

上游产品  9
126301-16-4 143-33-9 79069-13-9 773837-37-9
13435-20-6 24424-99-5 15761-38-3 109208-68-6
84765-24-2
下游产品  4
3775-72-2 158851-30-0 176982-57-3 679808-74-3

海关

海关编码	2926909090
中文概述	2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%