2272-11-9

• 常用中文名：油酸单乙醇胺
• 常用英文名：monoethanolamine oleate
• CAS号：2272-11-9
• 分子式：C₂₀H₄₁NO₃
• 分子量：343.54400
• 相关类别： 研究领域 心血管疾病
• 发布时间：2018-03-29 08:00:00
• 更新时间：2024-01-03 10:08:10
• 油酸(9-顺十八烯酸)乙醇胺由油酸和乙醇胺组成。油酸乙醇胺具有硬化治疗活性。油酸乙醇胺可引起静脉内膜内皮的炎症反应[1]。

名称

• 中文名: 油酸单乙醇胺
• 英文名: 2-aminoethanol,(Z)-octadec-9-enoic acid
• 英文别名: Neosclerol; Monolate; Ethamolin; Moramin; Monoethanolamine oleate; ETHANOLAMINE OLEATE; Oldamin; Varicetin; Varex

物化性质

• 密度: 0.973g/cm3
• 沸点: 170.9ºC at 760mmHg
• 分子式: C₂₀H₄₁NO₃
• 分子量: 343.54400
• 闪点: 93.3ºC
• 精确质量: 343.30900
• PSA: 83.55000
• LogP: 5.74620
• 蒸汽压: 3.7E-06mmHg at 25°C

生物活性

• 描述: 油酸(9-顺十八烯酸)乙醇胺由油酸和乙醇胺组成。油酸乙醇胺具有硬化治疗活性。油酸乙醇胺可引起静脉内膜内皮的炎症反应[1]。
• 相关类别:
  研究领域 >> 心血管疾病
  信号通路 >> 其他 >> 其他
  研究领域 >> 炎症/免疫
• 靶点:

  Inflammation[1]

• 参考文献:

  [1]. Kiripolsky MG. More on ethanolamine oleate as a vascular sclerosant. Dermatol Surg. 2010 Jul;36(7):1153-4.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RG2900000 CAS REGISTRY NUMBER : 2272-11-9 LAST UPDATED : 199701 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C18-H34-O2.C2-H7-N-O MOLECULAR WEIGHT : 343.62 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 156 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia REFERENCE : YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 17,357,1989 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 175 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Sense Organs and Special Senses (Eye) - lacrimation Gastrointestinal - changes in structure or function of salivary glands REFERENCE : YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 17,373,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X1228 No. of Facilities: 1996 (estimated) No. of Industries: 22 No. of Occupations: 31 No. of Employees: 40126 (estimated) No. of Female Employees: 2760 (estimated)

安全

• 海关编码: 2922499990

海关

海关编码	2922499990
中文概述	2922499990 其他氨基酸及其酯及它们的盐（含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:AB(入境货物通关单,出境货物通关单) 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
监管条件	A.入境货物通关单 B.出境货物通关单
检验检疫	P.进境动植物、动植物产品检疫 Q.出境动植物、动植物产品检疫 R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验
Summary	HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%