604-80-8

• 常用中文名：水仙苷
• 常用英文名：Narcissoside
• CAS号：604-80-8
• 分子式：C₂₈H₃₂O₁₆
• 分子量：624.544
• 相关类别： 生物化工 植物提取物
• 发布时间：2018-02-20 08:00:00
• 更新时间：2026-07-01 11:27:51
• Narcissin (Narcissoside) 是从 Morinda citrifolia 中分离的一种黄连糖苷,清除 ONOO- 和 SIN-1 衍生的 ONOO-, IC50 分别为 3.5 和 9.6 μM。具有抗氧化活性。

名称

• 中文名: 水仙苷
• 英文名: 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
• 中文别名: 水仙苷, 来源于黄毛耳草; 抑制剂Ncissoside; 水仙苷(标准品); 水仙苷; 异鼠李素-3-O-β-D-芸香糖苷; 异鼠李素-4-O-Β-D-芸香糖苷; 异鼠李素-3-O-芸香糖苷; 异鼠李素芸香糖苷; 水仙苷对照品; 水仙甙(水仙苷); 水仙苷(异鼠李素-3-O-Β 异鼠李素-3-芸香糖苷/水仙苷; 水仙苷,10 MM DMSO 溶液; 水仙苷;异鼠李素-4-O-β-D-芸香糖苷; 水仙苷/异鼠李素-3-O-芸香糖苷; D-芸香糖苷; 水仙苷(水仙甙; 水仙甙; 5,7-二羟基-2-(4-羟基-3-甲氧基苯基)-3-(((2S,3R,4S,5S,6R)-3,4,5-三羟基-6-(((2R,3R,4R,5R,6S)-3,4,5-三羟基-6-甲基四氢-2H-吡喃-2-基)氧基)甲基)四氢-2H-吡喃-2-基)氧基)-4H-苯并吡喃-4-酮; 水仙甙；异鼠李素-3-O-β-D-芸香糖苷；异鼠李素-3-O-芸香糖苷; 水仙苷(异鼠李素-3-O-Β-D-芸香糖苷,异鼠李素-3-O-芸香糖苷,水仙甙); 异鼠李素-3-O-Β-D-芸香糖苷; 异鼠李素-3-芸香糖甙/水仙苷; 异鼠李素-3-O-芸香糖苷(水仙苷); 异鼠李素-3-O-β-D-芸香糖苷
• 英文别名: Isorhamnetin-3-O-Rutinoside (15 mg); Ncissoside from Hedyotis chrysotricha; 4H-1-Benzopyran-4-one,3-[[6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl); ISORHAMNETIN-3-RUTINOSIDE hplc; Isorhamnetol 3-O-rutinoside; Ncissin (6CI, 7CI, 8CI); 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; Narcisin; Isorhamnetin Impurity 2; 5,7-Dihydroxy-2-(4-hydroxy-3-methoxy-phenyl)-3-[3,4,5-trihydroxy-6-(3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-2-yloxy]-1-benzopyran-4-one; Isorhamnetin 3-O-sutinoside; Ncissoside, froM Hedyotis chrysotricha; NCISSIN(ISORHAMNETIN-3-RUTINOSIDE)(SH); NCISSIN; ISORHAMNETIN-3-O-RUTINOSIDE; isorhamnetin3-rhamnoglucoside; 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-3-yl-6-O-(6-deoxy-α-D-mannopyranosyl)-β-D-glucopyranoside; isorhamnetin3-beta-rutinoside; NCISSIN(ISORHAMNETIN-3-RUTINOSIDE)(P); Narcissin; Ncissoside Ncissin; Isorhamnetin-3-O-Beta-D-rutinoside; Aids-089289; Isorhamnetin 3-rutinoside-RM; 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4-oxo-4H-chromen-3-yl 6-O-(6-deoxy-α-D-mannopyranosyl)-β-D-glucopyranoside; isorhaMnetin 3-O-β-D-rutinoside; 3'-O-Methylquercetin 3-rutinoside; Aids089289; 3-[[6-O-(6-Deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one; 3-O-Rutinosylisorhamnetin; 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-on; ncissoside; 6-O-(6-Désoxy-α-D-mannopyranosyl)-β-D-glucopyranoside de 5,7-dihydroxy-2-(4-hydroxy-3-méthoxyphényl)-4-oxo-4H-chromén-3-yle; Isorhamnetin 3-rhamnoglucoside; Ncissin, 10 mM in DMSO; 5,7-Dihydroxy-2-(4-hydroxy-3-méthoxyphényl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-méthyltétrahydro-2H-pyran-2-yl]oxy}méthyl)tétrahydro-2H-pyran-2-yl]oxy}-4H-chromén-4-one; 7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-osyl)oxy); Isorhamnetin 3-rutinoside; Isorhamnetin 3-O-rutinoside; 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one; 3-[[6-O-(6-Deoxy-alpha-L-mannopyranosyl)-beta-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-on; 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-({[(2S,3S,4S,5S,6R)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}methyl)tetrahydro-2H-pyran-2-yl]oxy}-4H-chromen-4-one; NCISIN; Isorhamnestin-3-O-rutinoside; 4h-benzopyran-4-one,3-((6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyran; Isorhamnetin-3-O-β-D-rutinoside; Isprhamnetin-3-rutinoside; ISORHAMNETIN-3-RUTINOSIDE; ncissin flavonol; 4H-1-Benzopyran-4-one, 3-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)

物化性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 953.1±65.0 °C at 760 mmHg
• 熔点: 182-184ºC
• 分子式: C₂₈H₃₂O₁₆
• 分子量: 624.544
• 闪点: 312.9±27.8 °C
• 精确质量: 624.169006
• PSA: 258.43000
• LogP: 1.73
• 外观性状: 粉末
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.728
• 储存条件: -20℃

生物活性

• 描述: Narcissin (Narcissoside) 是从 Morinda citrifolia 中分离的一种黄连糖苷,清除 ONOO- 和 SIN-1 衍生的 ONOO-, IC50 分别为 3.5 和 9.6 μM。具有抗氧化活性。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Su BN, et al. Chemical constituents of the fruits of Morinda citrifolia (Noni) and their antioxidant activity.J Nat Prod. 2005 Apr;68(4):592-5.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DJ2979500 CHEMICAL NAME : 4H-Benzopyran-4-one, 3-((6-O-(6-deoxy-alpha-L-mannopyranosyl)-beta-D-gluco pyranosyl)oxy)-5,7- dihydroxy-2-(4-hydroxy-3-methoxyphenyl)- CAS REGISTRY NUMBER : 604-80-8 LAST UPDATED : 199806 DATA ITEMS CITED : 1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >4 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DARUEE Dokl Akad Nauk resp. Uzb. Volume(issue)/page/year: (2),41,1992

安全

• 安全声明 (欧洲): 24/25
• 危险品运输编码: NONH for all modes of transport
• 海关编码: 29389090