114684-69-4

• 常用中文名：Cbz-氨基(二乙氧基磷酰基)乙酸甲酯
• 常用英文名：Benzyloxycarbonylamino-(diethoxy-phosphoryl)-acetic acid methyl ester
• CAS号：114684-69-4
• 分子式：C₁₅H₂₂NO₇P
• 分子量：359.31100
• 发布时间：2018-10-15 18:38:20
• 更新时间：2026-07-20 18:02:55

名称

• 中文名: N-CBZ-(二乙氧基磷酸基)氨基酸甲酯
• 英文名: Methyl 2-(((benzyloxy)carbonyl)amino)-2-(diethoxyphosphoryl)acetate
• 中文别名: 甲基2-(苄氧基羰基氨基)-2-(二乙氧基磷酰基)乙酸酯; CBZ-氨基(二乙氧基膦)乙酸甲酯; 乙酸,2-(二乙氧基膦酰基)-2-[[(苯基甲氧基)羰基]氨基]-,甲酯; CBZ-氨基(二乙氧基膦); 2-(Cbz-氨基)-2-(二乙氧基磷酰基)乙酸甲酯; cbz-氨基(二乙氧基膦)乙酸甲酯; 2-(((苄氧基)羰基)氨基)-2-二乙基磷乙酸 甲酯; 2-(苄基氧基羰基氨基)-2-(二乙氧基磷酰基)乙酸甲酯; N-CBZ-(二乙氧基磷酸基; CBZ-氨基-(二乙氧基磷酰基)-乙酸甲酯; 2-(((苄氧基)羰基)氨基)-2-(二乙氧基磷酰基)乙酸甲酯; 2-(苄氧羰基氨基)-2-(二乙氧基磷酰基)乙酸甲酯; 2-二乙氧磷酰基-N-CBZ-甘氨酸甲酯
• 英文别名: methyl 2-(benzyloxycbonylamino)-2-(diethoxyphosphoryl)acetate; methyl 2-(benzyloxycbonylamino)-2-(diethyloxyphosphoryl)acetate; Benzyloxycbonylamino-(diethoxy-phosphoryl)-acetic acid methyl ester; 2-(diethoxyphosphoryl); Methyl 2-(diethoxyphosphinyl)-2-[[(phenylmethoxy)carbonyl]amino]acetate; Acetic acid, 2-(diethoxyphosphinyl)-2-[[(phenylMethoxy)carbonyl]amino]-, Methyl ester; Methyl 2-(Cbz-amino)-2-(diethoxyphosphoryl)acetate; METHYL CBZ-AMINO(DIETHOXYPHOSPHORYL)ACETATE; ethyl2-(((benzyloxy)carbonyl)amino)-2-(diethoxyphosphoryl)acetate; methyl 2-diethoxyphosphoryl-2-(phenylmethoxycarbonylamino)acetate

物化性质

• 密度: 1.235g/cm3
• 沸点: 500.6ºC at 760mmHg
• 熔点: 79-81°C (lit.)
• 分子式: C₁₅H₂₂NO₇P
• 分子量: 359.31100
• 闪点: 256.6ºC
• 精确质量: 359.11300
• PSA: 109.97000
• LogP: 3.06890
• 外观性状: 浅黄色至黄棕色固体
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.501
• 储存条件: 2-8°C，惰性气体

安全

• 危害码 (欧洲): Xn

合成路线

78-40-0 127357-37-3 ~45% 114684-69-4

文献：HUTCHISON MEDIPHARMA LIMITED; SU, Wei-guo; DAI, Guangxiu; XIAO, Kun; JIA, Hong; ZHANG, Zhulin; VENABLE, Jennifer Diane; BEMBENEK, Scott Damian; CHAI, Wenying Patent: WO2014/15830 A1, 2014 ; Location in patent: Page/Page column 136; 137 ;

127357-37-3 122-52-1 ~88% 114684-69-4

文献：Ku, Bonchul; Oh, Dong Young Tetrahedron Letters, 1988 , vol. 29, # 35 p. 4465 - 4466

79002-45-2 ~% 114684-69-4

文献：Organic Letters, , vol. 7, # 12 p. 2385 - 2388

621-84-1 ~% 114684-69-4

文献：Organic Letters, , vol. 7, # 12 p. 2385 - 2388

127357-37-3 13716-45-5 ~39% 114684-69-4

文献：Ku, Bonchul; Oh, Dong Young Tetrahedron Letters, 1988 , vol. 29, # 35 p. 4465 - 4466

127357-37-3 ~% 114684-69-4

文献：Archiv der Pharmazie, , vol. 329, # 11 p. 503 - 509

64356-76-9 122-52-1 ~% 114684-69-4

文献：Archiv der Pharmazie, , vol. 329, # 11 p. 503 - 509

127357-37-3 120341-31-3 ~% 114684-69-4

文献：Tetrahedron Letters, , vol. 29, # 35 p. 4465 - 4466

上下游产品

上游产品  7
78-40-0 122-52-1 79002-45-2 621-84-1
13716-45-5 64356-76-9 120341-31-3
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