142217-81-0

• 常用中文名：恩替卡韦中间体N-1
• 常用英文名：2-amino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one
• CAS号：142217-81-0
• 分子式：C₂₆H₂₇N₅O₃
• 分子量：457.524
• 发布时间：2018-05-18 08:00:00
• 更新时间：2026-07-08 10:16:15

名称

• 中文名: 2-氨基-1,9-二氢-9-[(1S,3R,4S)-4-苄氧基-3-苄氧基甲基-2-亚甲基环戊基]-6H-嘌呤-6-酮
• 英文名: 2-amino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl)-1H-purin-6(9H)-one
• 中文别名: ET1恩替卡韦中间体; 2-氨基-1,9-二氢-9-[(1S,3R,4S)-4-苄氧基-3-苄氧基甲基-2-亚甲基环戊基]-6H-嘌呤-6-酮2-AMINO-1,9-DIHYDRO-9-[(1S,3R,4S)-4-(BENZYLOXY)-3-(BENZYLOXYMETHYL)-2-METHYLENECYCLOPENTYL]-6H-PURIN-6-ONE; 4-甲基嘧啶-2-基胺; 恩替卡韦中间体N8,2-氨基-1,9-二氢-9-[(1S,3R,4S)-4-苄氧基-3-苄氧基甲基-2-亚甲基环戊基]-6H-嘌呤-6-酮; 二苄基恩替卡韦(3',5'-二邻苄基恩替卡韦); 恩替卡韦中间体N-2; 恩替卡韦中间体ETA; 二苄基恩替卡韦; 3',5'-DI-O-苄基恩替卡韦; 2-氨基-9-((1S,3R,4S)-4-(苄氧基)-3-(苄氧基甲基)-2-亚甲基环戊基)-1H-嘌呤-6(9H)-酮; 2-氨基-1,9-二氢-9-[(1S,3R,4S)-4-苄氧基-3-苄氧基甲基-2-亚甲基环戊基]-6H-嘌呤-6-酮(恩替卡韦中间体9); 二苄基恩替卡韦(3',5'-二-O-苄基恩替卡韦); 3'.5'-二-O-苄基恩替卡韦; 2-氨基-1,9-二氢-9-[(1S,3R,4S)-4-苄氧基-3-苄氧基甲基-2-亚甲基环戊基]-6H-嘌呤-6-酮N-1; 恩替卡韦杂质4; 恩替卡韦中间体9; 恩替卡韦杂质45; 3 ',5 '-二-O-苄基恩替卡韦; 恩替卡韦中间体E8; 恩替卡韦中间体N8; 恩替卡韦中间体L; 恩替卡韦-8; 恩替卡韦-9; 2-氨基-9-((1S,3R,4S)-4-(苯甲氧基)-3-((苯甲氧基)甲基)-2-亚甲基环戊基)-1H-嘌呤-6(9H)-酮; 恩替卡韦二苄基化; 恩替卡韦杂质ETA(N8)
• 英文别名: 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-2-Methylene-4-(phenylMethoxy)-3-[(phenylMethoxy)Methyl]cyclopentyl]-6H-purin-6-one; 3',5'-Di-O-benzyl Entecavir; 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-p; 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4- (benzyloxy)-3- (benzyloxymethyl)-2-methylenecyclopentyl]}6H- purin-6-one(Ent-VIII); 2-Amino-9-{(1S,3R,4S)-4-(benzyloxy)-3-[(benzyloxy)methyl]-2-methylenecyclopentyl}-1,9-dihydro-6H-purin-6-one; 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxyMethyl)-2-Methylenecyclopentyl]-6H-purin; Entecavir InterMediate N-1; (1S,3R,4S)-2-amino-9-[4-(benzyloxy)-3-(benzyloxymethyl)-2-methylidene-cyclopentyl]-3H-purin-6-one; 3’,5’-Di-O-benzyl Entecavir; 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxy; Entecavir Impurity 16; Entecavir Impurity 4; ETA/ET1/N8; 6H-Purin-6-one,2-amino-1,9-dihydro-9[(1S,3R,4S)-2-methylene-4-(phenylmethoxy)-3-[([phenylmethoxy)methyl]cyclopentyl]; 2-Amino-9-((1S,3R,4S)-4-(benzyloxy)-3-((benzyloxy)-methyl)-2-methylenecyclopentyl)-1H-purin-6(9H); 2-amino-9-[(1S,3R,4S)-4-(benzyloxy)-3-[(benzyloxy)methyl]-2-methylidenecyclopentyl]-9H-purin-6-ol; Dibenzyl Entecavir (3',5'-Di-O-Benzyl Entecavir); Entecavir E8; 2-Amino-9-((1S,3R,4S)-4-(benzyloxy)-3-((benzyloxy)-methyl)-2-methylenecyclopentyl)-1H-purin-6(; Dibenzyl Entecavir; DIBENZYLOXY GUANINE INTERMEDIATE; 2-Amino-1,9-dihydro-9- [(1S, 3R, 4S) -4-benzyloxy-3-benzyloxymethyl-2-methylenecyclopentyl] -6H-purine-6-one; 2-amino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxyMethyl)-2-Methylenecyclopentyl)-1H-[C4]purin-6(9H)-one; 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one; Entecavir InterMediate VIII IsoMer; US-DMF No.; [1S-(1α,3α,4β)]-2-Amino-1,9-dihydro-9-[2-Methylene-4-(phenylMethoxy)-3-[(phenylMethoxy)Methyl]cyclopentyl]-6H; 2-amino-1,9-dihydro-9-[(1S,3R,4S)-2-Methylene-4-(benzyloxy)-3-[(benzyloxy)Methyl]cyclopentyl]-6H-Purin-6-one; Entecavir dibenzylated; Entecavir impurity SRR; 2-amino-9-((1S,3R,4S)-4-(benzyloxy)-3-(benzyloxyMethyl)-2-Methylenecyclopentyl)-9H-purin-6-ol; 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxyMethyl)-2-Methylenecyclopentyl]-6H-purin-6-one (interMediate 7); 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-(benzyloxy)-3-(benzyloxymethyl)- 2-methylenecyclopentyl]-6H; Entecavir-9; 2-AMINO-9-((1S,3R,4S)-4-(BENZYLOXY)-3-(BENZYLOXYMETHYL)-2-METHYLENECYCLOPHENTYL)-1H-PURIN-6(9H)-ONE; N-1 Entecavir API; Entecavir Dibenzyl Impurity

物化性质

• 密度: 1.3±0.1 g/cm3
• 分子式: C₂₆H₂₇N₅O₃
• 分子量: 457.524
• 精确质量: 457.211395
• PSA: 108.05000
• LogP: 3.97
• 折射率: 1.679
• 储存条件: 室温，干燥

合成路线

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