110567-22-1

• 常用中文名：(1S,2R,3S,5R)-3-(苯甲氧基)-2-[(苯甲氧基)甲基]-6-氧杂双环[3.1.0]己烷
• 常用英文名：(1S,2R,3S,5R)-3-phenylmethoxy-2-(phenylmethoxymethyl)-6-oxabicyclo[3.1.0]hexane
• CAS号：110567-22-1
• 分子式：C₂₀H₂₂O₃
• 分子量：310.387
• 相关类别： 医药中间体 原料药中间体
• 发布时间：2018-12-09 12:43:49
• 更新时间：2026-07-01 16:16:19

名称

• 中文名: (1S,2R,3S,5R)-3-(苄氧基)-2-[(苄氧基)甲基]-6-氧杂二环[3.1.0]己烷
• 英文名: (1S,2R,3S,5R)-3-phenylmethoxy-2-(phenylmethoxymethyl)-6-oxabicyclo[3.1.0]hexane
• 中文别名: (1S,2R,3S,5R)-3-(苄氧基)-2-((苄氧基)甲基)-6-氧杂双环[3.1.0]己烷; [1S-(1Α,2Α,3Β,5Α)]-3-(苯甲氧基)-2-[(; (1S,2R,3S,5R)-3-(苄氧甲基)-6-氧杂二环[3.1.0]己烷; (1S,2R,3S,5R)-2-苄氧基甲基-3-苄氧基-6-氧-二环[3.1.0]己烷; 恩替卡韦杂质48; 恩替卡韦杂质25; 恩替卡韦杂质N3; 恩替卡韦中间体3; 恩替卡韦-3 (1S,2R,3S,5R)-3-(苯甲氧基)-2-[(苯甲氧基)甲基]-6-氧杂双环[3.1.0]己烷; 恩替卡韦-6; 恩替卡韦中间体三; 恩替卡韦杂质; 恩替卡韦中间体N3
• 英文别名: (1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-o; (1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane###110-1; (1S,2R,3S,5R)-3-(Benzyloxy)-2-((benzyloxy)Methyl)-6-oxabicyclo[3.1.0]hexane; (1S,2R,3S,5R)-3-(Benzyloxy)-2-[(benzyloxy)methyl]-6-oxabicyclo[3.1.0]hexane; (1S,2R,3S,5R)-3-(Benzyloxy)-2-[(benzyloxy)methyl]-6-oxabicyclo[3.1.0]hexan; Entecavir Impurity N3; Entecavir E3; [1S-(1a,2a,3,5a)]-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane; 6-Oxabicyclo[3.1.0]hexane, 3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-, (1S, 2R, 3S, 5R); [1S-(1α,2α,3β,5α)]-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane; )-6-oxabicycL; (2R,3S)-benzyloxy-2-benzyloxymethyl-6-oxabicyclo<3.1.0>hexane; (1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane; oxy)-2-((benzyL; 1R,2R-2-[(Phenylmethoxy)methyl]-3-cyclo penten-1-ol; Entecavir-3; (1S,2R,3S,5R)-3-(BenzyL; Entecavir Impurity; (1S,2R,3S,5R)-3-(benzyloxy)-2-(benzyloxymethyl)-6-oxabicyclo[3.1.0]hexane; Entecavir Impurity 48; (1S,2R,3S,5R)-3-(Benzyloxymethyl)-6-oxabicyclo[3.1.0]hexane; (1S,2R,3S,5R)-3-(Benzyloxy)-2-((benzyloxy)methyl)-6-oxabicyclo[3,1,0]hexane; (1S,2R,3S,5R)-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane; (1S,2R,3S,5R)-3-(Phenymethyloxy)-2-(phenylmethoxy)methyl-6-oxabicyclo[3.1.0]hexane ISO 9001：2015 REACH; Entecavir InterMediate III; 1S-(1α,2α,3β,5α)]-3-(Phenylmethoxy)-2-[(phenylmethoxy)methyl]-6-oxabicyclo[3.1.0]hexane; Entecavir Intermediate N7; (1S,2R,3S,5R)-3-(PhenylMethoxy)-2-[(phenylMethoxy)Methyl]-6-oxabicyclo[3.1.]hexane; (1R,5S)-3-[(benzyloxy)Methyl]-6-oxabicyclo[3.1.0]hexane

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 427.9±40.0 °C at 760 mmHg
• 分子式: C₂₀H₂₂O₃
• 分子量: 310.387
• 闪点: 145.9±24.6 °C
• 精确质量: 310.156891
• PSA: 30.99000
• LogP: 4.35
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.593
• 储存条件: Refrigerator

安全

• 危害码 (欧洲): Xi
• 海关编码: 2932999099

合成路线

100-39-0 117641-39-1 ~85% 110567-22-1

文献：Synthesis, , # 13 p. 2101 - 2109

3587-60-8 ~% 110567-22-1

文献：Synthesis, , # 13 p. 2101 - 2109

39939-07-6 ~% 110567-22-1

文献：Synthesis, , # 13 p. 2101 - 2109

110567-21-0 ~% 110567-22-1

文献：Synthesis, , # 13 p. 2101 - 2109

542-92-7 ~% 110567-22-1

文献：Synthesis, , # 13 p. 2101 - 2109

4984-82-1 ~% 110567-22-1

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132

上下游产品

上游产品  7
100-39-0 117641-39-1 3587-60-8 39939-07-6
110567-21-0 542-92-7 4984-82-1
下游产品  7
110567-23-2 142217-79-6 142217-81-0 142217-69-4
142217-77-4 142217-80-9 142217-78-5

海关

海关编码	2932999099
中文概述	2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%