142217-77-4

• 常用中文名：(1S,2S,3S,5S)-5-(2-氨基-6-苄氧基-9H-嘌呤-9-基)-3-苄氧基-2-苄氧基甲基环戊醇
• 常用英文名：(1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol
• CAS号：142217-77-4
• 分子式：C₃₂H₃₃N₅O₄
• 分子量：551.635
• 发布时间：2018-12-02 12:07:40
• 更新时间：2026-06-30 10:28:41

名称

• 中文名: (1S,2S,3S,5S)-5-(2-氨基-6-苄氧基-9H-嘌呤-9-基)-3-苄氧基-2-苄氧基甲基环戊醇
• 英文名: (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol
• 中文别名: 恩替卡韦4中间体; 恩替卡韦中间体四; [1S-(1Α,2Β,3Α,5Β)]-5-[2-氨基-6-(苯甲; (1S,2R,3S,5S)-5-(2-氨基-6-苄氧基-9H-嘌呤-9-基)-3-苄氧基-2-苄氧基甲基环戊醇; 恩替卡韦杂质32; (1S,2S,3S,5S)-5-(2-氨基-6-苄氧基-9H-嘌呤-9-基)-3-苄氧基-2; N4(1S,2S,3S,5S)-5-(2-氨基-6-苄氧基-9H-嘌呤-9-基)-3-苄氧基-2-苄氧基甲基环戊醇; (1S,2S,3S,5S)-5-(2-氨基-6-苄氧基-9H-嘌呤-9-基)-3-苄氧基-2-苄氧基甲基环戊醇(N4); 恩替卡韦中间体4; (1S,2S,3S,5S)-5-(2-氨基-6-(苯甲氧基)-9H-嘌呤-9-基)-3-(苯甲氧基)-2-(苯甲氧基甲基)环戊醇; 恩替卡韦-4; 恩替卡韦中间体N-6; (1S,2S,3S,5S)-5-(2-氨基-6-苄氧基-9H-嘌呤-9-基)-3-苄氧基-2-苄氧基甲基环戊醇N-6; (1S,2S,3S,5S)-5-(2-氨基-6-苄氧基-9H-嘌呤-9-基)-3-苄氧基-2-苄氧基甲基环戊醇(1S,2S,3S,5S)-5-(2-AMINO-6-(BENZYLOXY)-9H-PURIN-9-YL)-3-(BENZYLOXY)-2-(BENZYLOXYMETHYL)CYCLOPENTANOL; 恩替卡韦 N4; (1S,2S,3S,5S)-5-(2-氨基-6-苄氧基-9H-嘌呤-9-基)-3-苄氧基-2-苄氧基甲基环戊醇/恩替卡韦中间体4; (1S,2S,3S,5S)-2-(苄氧基甲基)-3-(苄氧基)-5-[2-氨基-6-(苄氧基)-9H-嘌呤-9-基]环戊醇; 恩替卡韦中间体N4
• 英文别名: (1S,2S,3S,5S)-5-[2-Amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]cyclopentanol; (1S,2S,3S,5S)-5-[2-Amino-6-(benzyloxy)-9H-purin-9-yl]-3-(benzyloxy)-2-[(benzyloxy)methyl]cyclopentanol; ETD/ET4/N4; (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cydopentanol; TIANFU-CHEM (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol; (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxyMethyl)cyclopentanol (interMediate st3); Ente-4; Entecavir-4; (1S,2S,3S,5S)-5-(2-amino-6-phenylmethoxy-9-purinyl)-3-phenylmethoxy-2-(phenylmethoxymethyl)-1-cyclopentanol; Entecavir intermediate N4; (1S,2S,3S,5S)-5-(2-amino-6-phenylmethoxypurin-9-yl)-3-phenylmethoxy-2-(phenylmethoxymethyl)cyclopentan-1-ol; (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclope; (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopenta; (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl) cyclopentano; （1S,2R,3S,5S）-5-(2-amino-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-(benzyloxymethyl)cyclopentanol; Entecavir Tribenzyl Alcohol; (1S,2S,3S,5S)-5-(2-Amino-6-(benzyloxy)-9H-purin-9-yl)-3-(ben; Entecavir InterMediate IV; Cyclopentanol, 5-[2-amino-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-, (1S,2S,3S,5S); Entecavir E4; (1S,2S,3S,5S)-5-[2-amino-6-(benzyloxy)-9H-purin-9-yl]-3-(benzyloxy)-2-[(benzyloxy)methyl]cyclopentan-1-ol

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 780.5±70.0 °C at 760 mmHg
• 分子式: C₃₂H₃₃N₅O₄
• 分子量: 551.635
• 闪点: 425.9±35.7 °C
• 精确质量: 551.253235
• PSA: 117.54000
• LogP: 5.32
• 蒸汽压: 0.0±2.8 mmHg at 25°C
• 折射率: 1.670
• 储存条件: 室温，避光，保存于惰性气体中

合成路线

110567-22-1 19916-73-5 ~60% 142217-77-4

文献：Bisacchi; Chao; Bachard; Daris; Innaimo; Jacobs; Kocy; Lapointe; Martel; Merchant; Slusarchyk; Sundeen; Young; Colonno; Zahler Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 2 p. 127 - 132

3587-60-8 ~% 142217-77-4

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132

39939-07-6 ~% 142217-77-4

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132

117641-39-1 ~% 142217-77-4

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132

110567-21-0 ~% 142217-77-4

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132

4984-82-1 ~% 142217-77-4

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132

上下游产品

上游产品  7
110567-22-1 19916-73-5 3587-60-8 39939-07-6
117641-39-1 110567-21-0 4984-82-1
下游产品  5
142217-79-6 142217-81-0 142217-69-4 142217-80-9
142217-78-5