240401-09-6

• 常用中文名：3-羟基-1-氧杂-8-氮杂螺[4.5]癸烷-8-羧酸叔丁酯
• 常用英文名：N-Boc-1-Oxa-8-azaspiro[4.5]decan-3-ol
• CAS号：240401-09-6
• 分子式：C₁₃H₂₃NO₄
• 分子量：257.326
• 发布时间：2019-01-02 17:51:42
• 更新时间：2024-01-13 15:33:07

名称

• 中文名: N-叔丁氧羰基-1-氧杂-8-氮杂螺[4.5]癸烷-3-醇
• 英文名: tert-butyl 3-hydroxy-1-oxa-8-azaspiro[4.5]decane-8-carboxylate
• 中文别名: N-boc-1-噁-8-氮杂螺[4.5]-3-癸醇; 3-羟基-1-氧杂-8-氮杂螺[4.5]癸烷-8-羧酸叔丁酯
• 英文别名: 1-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid, 3-hydroxy-, 1,1-dimethylethyl ester; 3-Hydroxy-1-oxa-8-azaspiro[4.5]decane-8-carboxylic acid tert-butyl ester; tert-butyl 3-hydroxy-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; tert-butyl3-hydroxy-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; tert-butyl (3RS)-3-hydroxy-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; 1-Oxa-8-azaspiro[4.5]decane-8-carboxylicacid,3-hydroxy-,1,1-dimethylethyl ester; tert-butyl 1-oxa-8-azaspiro[4.5]decan-3-ol-8-carboxylate; 2-Methyl-2-propanyl 3-hydroxy-1-oxa-8-azaspiro[4.5]decane-8-carboxylate; N-Boc-1-Oxa-8-azaspiro[4.5]decan-3-ol; tert-Butyl-3-hydroxy-1-oxa-8-azaspiro[4.5]decan-8-carboxylat

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 391.0±42.0 °C at 760 mmHg
• 分子式: C₁₃H₂₃NO₄
• 分子量: 257.326
• 闪点: 190.3±27.9 °C
• 精确质量: 257.162720
• PSA: 59.00000
• LogP: 0.52
• 外观性状: 液体
• 蒸汽压: 0.0±2.0 mmHg at 25°C
• 折射率: 1.521
• 储存条件: 2-8℃，惰性气体

安全

• 危害码 (欧洲): Xi
• 海关编码: 2934999090

合成路线

757239-75-1 ~49% 240401-09-6

文献：MERCK SHARP and DOHME LIMITED Patent: WO2004/78750 A1, 2004 ; Location in patent: Page 88-89 ; WO 2004/078750 A1

203662-51-5 ~35% 240401-09-6

文献：PFIZER INC.; LONG, Scott Allen; MEYERS, Marvin Jay; PELC, Matthew James; SCHWEITZER, Barbara Ann; THORARENSEN, Atli; WANG, Lijuan Jane Patent: WO2010/58318 A1, 2010 ; Location in patent: Page/Page column 26 ; WO 2010/058318 A1

240401-08-5 ~% 240401-09-6

文献：US6498159 B1, ;

954236-44-3 ~% 240401-09-6

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 21 p. 6545 - 6553

上下游产品

上游产品  3
757239-75-1 203662-51-5 954236-44-3
下游产品  2
954236-44-3 898157-46-5

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%