108-91-8

108-91-8结构式

常用中文名：环己胺
常用英文名：Cyclohexylamine
CAS号：108-91-8
分子式：C₆H₁₃N
分子量：99.174
相关类别：有机原料氨基化合物环烷胺、芳香单胺、芳香多胺及其衍生物和盐
发布时间：2018-02-08 08:00:00
更新时间：2024-01-01 18:25:06
【用途一】
用于制造活性染料、柔软剂VS和医药克脑迷噻替泒、亚胺醌等，也可用于医药、农药上。
【用途二】
用于有机合成、塑料合成，也用作防腐剂和酸性气体吸收剂
【用途三】
用作橡胶硫化促进剂，也用作合成纤维、染料、气相缓蚀剂的原料
【用途四】
环己胺是除草剂环嗪酮的中间体，也是橡胶促进剂、石油添加剂、阻蚀剂的中间体。
【用途五】
本品用以制备环己醇、环己酮、己内酰胺、醋酸纤维和尼龙6等。环己胺本身为溶剂，可在树脂、涂料、脂肪、石蜡油类中应用。也可用于制取脱硫剂、橡胶抗氧剂、硫化促进剂、塑料及纺织品化学助剂、锅炉给水处理剂、金属缓蚀剂、乳化剂、防腐剂、抗静电剂、胶乳凝固剂、石油添加剂、杀菌剂、杀虫剂及染料中间体。环己胺的磺酸盐，作为人工甘味料，用于食品、饮料和医药。
【用途六】
酸性气体吸收剂，有机合成。

中文名	环己胺
英文名	cyclohexylamine
中文别名	六氢苯胺环已基氨基环己烷L 六氢化苯胺氨基环己烷六氢化苯胺氨基环已烷环已胺
英文别名	N-Cyclohexylamine Benzenamine, hexahydro- CHA-60 1-Cyclohexylamine Cyclohexylamine hexahydro-anilin Cyclohexylamin Hexahydroaniline cyclohexyl amine cyclohexaneamine monocyclohexyl amine cyclohexyl-amine 1-Aminocyclohexane NH2-cyclo-C6H11 EINECS 203-629-0 Aniline, hexahydro- 1-AMINO-CYCLOHEXANE aminohexahydrobenzene Cyclohexanamine CHA Aminocyclohexane MFCD00001486 Glipizide Impurity 2

密度	0.9±0.1 g/cm3
沸点	134.5±0.0 °C at 760 mmHg
熔点	-17 °C
分子式	C₆H₁₃N
分子量	99.174
闪点	32.2±0.0 °C
精确质量	99.104797
PSA	26.02000
LogP	1.39
外观性状	透明至黄色液体
蒸汽密度	3.42 (vs air)
蒸汽压	8.1±0.2 mmHg at 25°C
折射率	1.460
储存条件	1.储存注意事项储存于阴凉、通风的库房。远离火种、热源。库温不宜超过30℃。保持容器密封。应与酸类、食用化学品分开存放，切忌混储。采用防爆型照明、通风设施。禁止使用易产生火花的机械设备和工具。储区应备有泄漏应急处理设备和合适的收容材料。 2.环己胺呈强碱性，能吸收空气中二氧化碳而迅速生成白色结晶的碳酸盐。因此，贮存包装应密闭。采用铁桶包装，每桶150kg或170kg。贮存在阴凉、通风、干燥处。防止日晒。隔绝热源和火源。按易燃、有毒化学品规定贮运。
稳定性	1.化学性质：具有伯胺的化学性质。有强碱性，在空气中吸收二氧化碳生成白色晶体的碳酸盐。能与酰氯、酸酐、酯反应生成N-酰化物。与亚硝酸反应得到醇。在碱性溶液中与甲醛反应生成羟甲基化合物。与二硫化碳反应生成二硫代氨基甲酸。与醛类反应生成Schiff 碱。 2.环己胺呈强碱性，因此刺激皮肤和黏膜。吸入蒸气可引起恶心和麻醉，经皮肤吸收能引起过敏症。小鼠吸入LC1004.3mg/L，MLC0.1mg/L。工作场所空气中最高容许浓度1mg/m3。设备要密闭，装置内要通风，操作人员戴防护用具。 3.稳定性稳定 4.禁配物酸类、酰基氯、酸酐、强氧化剂 5.避免接触的条件受热 6.聚合危害不聚合 7.分解产物氨
水溶解性	MISCIBLE
凝固点	-17.7℃
分子结构	1、摩尔折射率：31.22 2、摩尔体积（cm³/mol）：114.0 3、等张比容（90.2K）：270.1 4、表面张力（dyne/cm）：31.4 5、介电常数：无可用的 6、极化率：12.37 7、单一同位素质量：99.104799 Da 8、标称质量：99 Da 9、平均质量：99.1741 Da
计算化学	1.疏水参数计算参考值（XlogP）:无 2.氢键供体数量:1 3.氢键受体数量:1 4.可旋转化学键数量:0 5.互变异构体数量:无 6.拓扑分子极性表面积26 7.重原子数量:7 8.表面电荷:0 9.复杂度:46.1 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1
更多	1.性状：无色至黄色液体，有强烈的氨味。 2.pH值：10.5（1%溶液） 3.熔点（℃）：-17.7 4.沸点（℃）：134.5 5.相对密度（水=1）：0.86 6.相对蒸气密度（空气=1）：3.42 7.饱和蒸气压（kPa）：1.2（20℃） 8.临界压力（MPa）：4.2 9.辛醇/水分配系数：1.49 10.闪点（℃）：26（CC） 11.引燃温度（℃）：293 12.爆炸上限（%）：9.4 13.爆炸下限（%）：1.5 14.溶解性：溶于水，可混溶于多数有机溶剂。

国标编号:	82021
ＣＡＳ:	108-91-8
中文名称:	环己胺
英文名称:	Cyclohexylamine；Hexahydroaniline
别名:	六氢苯胺；氨基环己烷
分子式:	C₆H₁₃N；(CH₂)₅CHNH₂
分子量:	92.19
熔点:	-17.7℃ 沸点：134.5?
密度:	相对密度(水=1)0.86；
蒸汽压:	32℃/开杯( 蒸汽压 1.17kPa/25℃ )
溶解性:	溶于水，可混溶于多数有机溶剂
稳定性:	稳定
外观与性状:	无色液体，有不愉快的气味
危险标记:	20(碱性腐蚀品)34(易燃液体)
用途:	用作锅炉水处理剂及腐蚀抑制剂，橡胶促进剂，有机合成中间体

2.对环境的影响: 一、健康危害侵入途径：吸入、食入、经皮吸收。健康危害：吸入本品蒸气可发生急性中毒。中毒表现有剧烈呕吐及腹泻；瞳孔散大和对光反应迟钝、视力模糊、萎糜、语言障碍。环己胺有刺激作用，可使皮肤损伤和致敏。二、毒理学资料及环境行为急性毒性：LD50710mg/kg(大鼠经口)；227mg/kg(兔经皮)；LC507500mg/m3 (大鼠吸入) 刺激性：人经皮：125mg(48小时)，严惩刺激。致突变性：DNA抑制：人Hela 细胞100ug/L。显性致死实验：小鼠腹腔500mg/kg。生殖毒性：大鼠经口最低中毒剂量(TDL0)：5600mg/kg(雄性酱前用药4周)，对精子产生影响。小鼠经口最低中毒剂量(TDL0)：600mg/kg(孕6至11天用药)，胚泡植入后死亡率升高，胎鼠死亡。危险特性：遇明火、高热易燃。与氧化剂能发生强烈反应。若遇高热，容器内压增大，有开裂和爆炸的危险。燃烧(分解)产物：一氧化碳、二氧化碳、氧化氮。 3.现场应急监测方法: 　 4.实验室监测方法: 气相色谱法(大气)《现代环境监测方法》张晓林等主编 5.环境标准: 前苏联车间空气中有害物质的最高容许浓度 1mg/m3 6.应急处理处置方法: 一、泄漏应急处理疏散泄漏污染区人员至安全区，禁止无关人员进入污染区，切断火源。建议应急处理人员戴自给式呼吸器，穿化学防护服。不要直接接触泄漏物，在确保安全情况下堵漏。喷水雾会减少蒸发，但不能降低泄漏物在受限制空间内的易燃性。用沙土、干燥石灰或苏打灰混合，然后收集运至废物处理场所处置。也可以用大量水冲洗，经稀释的洗水放入废水系统。如大量泄漏，收集回收或无害处理后废弃。废弃物处置方法：用焚烧法。焚烧炉排出的氮氧化物通过洗涤器或高温装置除去。二、防护措施呼吸系统防护：可能接触其蒸气时，佩带防毒面具。紧急事态抢救或逃生时，佩带自给式呼吸器。眼睛防护：戴化学安全防护眼镜。防护服：穿工作服(防腐材料制作)。手防护：戴橡皮手套。其它：工作现场禁止吸烟、进食和饮水。工作后，淋浴更衣。进行就业前和定期的体检。三、急救措施皮肤接触：脱去污染的衣着，立即用流动清水彻底冲洗。若有灼伤，就医治疗。眼睛接触：立即提起眼睑，用大量流动清水彻底冲洗。吸入：迅速脱离现场至空气新鲜处。必要时进行人工呼吸。就医。食入：误服者立即漱口，给饮牛奶或蛋清。就医。灭火方法：雾状水、二氧化碳、砂土、抗溶性泡沫、干粉。

毒理学数据:

1.急性毒性

LD50：11mg/kg（大鼠经口）；227mg/kg（兔经皮）

LC50：7750mg/m³（大鼠吸入）

2.刺激性人经皮：125mg（48h），重度刺激。

3.致突变性 DNA抑制：人Hela细胞100μg/L。显性致死实验：小鼠腹腔500mg/kg。细胞遗传学分析：人类白细胞10μmol/L（5h）。

4.致癌性 IARC致癌性评论：G3，对人及动物致癌性证据不足。

5.其他大鼠经口最低中毒剂量（TDLo）：5600mg/kg（雄性交配前用药4周），对精子产生影响。小鼠经口最低中毒剂量（TDLo）：600mg/kg（孕6~11d用药），胚泡植入后死亡率升高，胎鼠死亡。

生态学数据:

1.该物质对环境有危害，应特别注意对水体的污染。吸入蒸气可发生急性中毒。对皮肤、眼和黏膜有刺激性和腐蚀性，经皮肤吸收能引起过敏症。

2.生态毒性

LC50：90mg/L（96h）（虹鳟鱼，静态）；

EC50：20mg/L（96h）（绿藻）；80mg/L（24h）（水蚤）

3.生物降解性 MITI-I测试，初始浓度100ppm，污泥浓度30ppm，2周后降解61.1%。

4.非生物降解性空气中，当羟基自由基浓度为5.00×10⁵个/cm³时，降解半衰期为7h（理论）。

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GX0700000

CHEMICAL NAME :: Cyclohexylamine

CAS REGISTRY NUMBER :: 108-91-8

BEILSTEIN REFERENCE NO. :: 0471175

LAST UPDATED :: 199806

DATA ITEMS CITED :: 81

MOLECULAR FORMULA :: C6-H13-N

MOLECULAR WEIGHT :: 99.20

WISWESSER LINE NOTATION :: L6TJ AZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Human

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 11 mg/kg

TOXIC EFFECTS :: Behavioral - food intake (animal) Lungs, Thorax, or Respiration - pulmonary emboli Gastrointestinal - other changes

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 7500 mg/m3

TOXIC EFFECTS :: Behavioral - excitement Behavioral - muscle contraction or spasticity

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation) Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 224 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1070 mg/m3

TOXIC EFFECTS :: Behavioral - excitement Behavioral - muscle contraction or spasticity

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 129 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1150 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 770 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 150 ppm/7H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 320 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 500 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1200 ppm/7H

TOXIC EFFECTS :: Lungs, Thorax, or Respiration - other changes

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Brain and Coverings - other degenerative changes Vascular - shock Liver - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 35700 mg/kg/1Y-C

TOXIC EFFECTS :: Liver - other changes Kidney, Ureter, Bladder - other changes

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 700 mg/m3/2H/9W-I

TOXIC EFFECTS :: Cardiac - changes in heart weight Kidney, Ureter, Bladder - changes in bladder weight Related to Chronic Data - death

TYPE OF TEST :: TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 100 mg/m3/4H/22W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - changes in bladder weight Blood - changes in cell count (unspecified) Nutritional and Gross Metabolic - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 5600 mg/kg

SEX/DURATION :: male 4 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 300 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - other measures of fertility

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 100 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Unreported

DOSE :: 5 mg/kg

SEX/DURATION :: male 1 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 600 mg/kg

SEX/DURATION :: female 6-11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 120 mg/kg

SEX/DURATION :: female 6-11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 61 mg/kg

SEX/DURATION :: female 11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 77 mg/kg

SEX/DURATION :: female 11 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

DOSE :: 200 mg/kg

SEX/DURATION :: female 10 day(s) after conception

TOXIC EFFECTS :: Reproductive - Fertility - other measures of fertility

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Parenteral

DOSE :: 250 mg/kg

SEX/DURATION :: male 5 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 14 gm/kg

SEX/DURATION :: male 8 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 15750 mg/kg

SEX/DURATION :: male 9 week(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: Dominant lethal test

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Mammal - species unspecified Kidney

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 8,617,1970 *** REVIEWS *** ACGIH TLV-Not classifiable as a human carcinogen DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 ACGIH TLV-TWA 41 mg/m3 (10 ppm) DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Animal Limited Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,178,1987 IARC Cancer Review:Animal NO EVIDENCE IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 22,55,1980 IARC Cancer Review:Human Inadequate Evidence IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 22,55,1980 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,178,1987 TOXICOLOGY REVIEW MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 39,1,1976 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 10 ppm (40 mg/m3) JAN 1993 OEL-AUSTRIA:TWA 10 ppm (40 mg/m3) JAN 1993 OEL-BELGIUM:TWA 10 ppm (41 mg/m3) JAN 1993 OEL-DENMARK:TWA 10 ppm (40 mg/m3);Skin JAN 1993 OEL-FINLAND:STEL 10 ppm (40 mg/m3);Skin JAN 1993 OEL-FRANCE:TWA 10 ppm (40 mg/m3) JAN 1993 OEL-GERMANY:TWA 10 ppm (40 mg/m3) JAN 1993 OEL-HUNGARY:TWA 1 mg/m3;STEL 2 mg/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 10 ppm (40 mg/m3);Skin JAN 1993 OEL-RUSSIA:STEL 1 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 10 ppm (40 mg/m3);STEL 20 ppm;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 10 ppm (40 mg/m3);Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO CYCLOHEXYLAMINE-air:10H TWA 10 ppm REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84526 No. of Facilities: 3468 (estimated) No. of Industries: 63 No. of Occupations: 25 No. of Employees: 9450 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84526 No. of Facilities: 4729 (estimated) No. of Industries: 83 No. of Occupations: 47 No. of Employees: 64346 (estimated) No. of Female Employees: 2914 (estimated)

符号	GHS02, GHS05, GHS06, GHS08
信号词	Danger
危害声明	H226-H301 + H311-H314-H361f
警示性声明	Missing Phrase - N15.00950417-P210-P280-P303 + P361 + P353-P305 + P351 + P338-P370 + P378
个人防护装备	Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
危害码 (欧洲)	C:Corrosive
风险声明 (欧洲)	R10;R21/22;R34
安全声明 (欧洲)	S36/37/39-S45-S1/2
危险品运输编码	UN 2357 8/PG 2
WGK德国	1
RTECS号	GX0700000
包装等级	II
危险类别	8
海关编码	2921300090

上游产品 9
19573-22-9 108-94-1 1122-60-7 100-64-1
108-93-0 6628-00-8 25070-80-8 84452-37-9
2562-37-0
下游产品 10
106637-58-5 107969-85-7 10450-11-0 1212-29-9
95-55-6 10354-56-0 109795-71-3 104960-66-9
105802-63-9 1042-35-9

1.由苯胺催化加氢而得，可分为常压法和加压法。此外，通过环己烷或环己醇的催化氨解，硝基环己烷还原，以及氢存在下的环己酮催化氨解等方法均可制得环己胺。

精制方法：常含有苯胺和水等杂质。精制时首先将环己胺转变为盐酸盐，用水重结晶，精制后在碱性溶液中用乙醚萃取，固体氢氧化钾干燥，在氮气流中蒸馏。在4.65KPa的压力下精馏，可将苯胺除去。

2.以镍或钴为催化剂，在高温、高压下由苯胺进行催化还原得到。也可由苯酚催化还原得到环己醇，氧化为环己酮，再与氨进行氨基化而得到环己胺。

海关编码	2921300090
中文概述	2921300090 其他环（烷，烯，萜烯）单胺或多胺（包括其衍生物及它们的盐）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2921300090 other cyclanic, cyclenic or cyclotherpenic mono- or polyamines, and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

108-91-8	101-83-7
18683-91-5	355-68-0
34066-58-5	20190-03-8
4998-76-9	372-46-3
1541-25-9	20227-92-3
1158522-08-7	940364-43-2
134104-43-1	131615-57-1
6906-52-1	930439-75-1
1018584-77-4	1375289-11-4
849349-65-1	127437-46-1