CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
TK8750000
-
CHEMICAL NAME :
-
Piperazine, 1,4-bis(1,4-benzodioxan-2-ylmethyl)-
-
CAS REGISTRY NUMBER :
-
7762-32-5
-
LAST UPDATED :
-
199012
-
DATA ITEMS CITED :
-
3
-
MOLECULAR FORMULA :
-
C22-H26-N2-O4
-
MOLECULAR WEIGHT :
-
382.50
-
WISWESSER LINE NOTATION :
-
T66 BO EOJ C1- AT6N DNTJ D1- CT66 BO EOJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intraperitoneal
-
SPECIES OBSERVED :
-
Rodent - mouse
-
DOSE/DURATION :
-
600 mg/kg
-
TOXIC EFFECTS :
-
Details of toxic effects not reported other than lethal dose value
-
REFERENCE :
-
JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 5,1285,1962
-
TYPE OF TEST :
-
LDLo - Lowest published lethal dose
-
ROUTE OF EXPOSURE :
-
Intravenous
-
SPECIES OBSERVED :
-
Mammal - dog
-
DOSE/DURATION :
-
50 mg/kg
-
TOXIC EFFECTS :
-
Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands
-
REFERENCE :
-
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 12,355,1953
-
TYPE OF TEST :
-
LD50 - Lethal dose, 50 percent kill
-
ROUTE OF EXPOSURE :
-
Intravenous
-
SPECIES OBSERVED :
-
Rodent - rabbit
-
DOSE/DURATION :
-
43 mg/kg
-
TOXIC EFFECTS :
-
Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands
-
REFERENCE :
-
FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 12,355,1953
|
