CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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TK8750000
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CHEMICAL NAME :
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Piperazine, 1,4-bis(1,4-benzodioxan-2-ylmethyl)-
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CAS REGISTRY NUMBER :
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7762-32-5
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LAST UPDATED :
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199012
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C22-H26-N2-O4
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MOLECULAR WEIGHT :
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382.50
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WISWESSER LINE NOTATION :
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T66 BO EOJ C1- AT6N DNTJ D1- CT66 BO EOJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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600 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 5,1285,1962
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Mammal - dog
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DOSE/DURATION :
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50 mg/kg
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TOXIC EFFECTS :
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Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands
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REFERENCE :
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FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 12,355,1953
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rabbit
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DOSE/DURATION :
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43 mg/kg
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TOXIC EFFECTS :
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Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands
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REFERENCE :
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FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 12,355,1953
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