| 中文名 | 氰化钾-13C,15N |
|---|---|
| 英文名 | potassium,azanylidynemethane |
| 英文别名 |
13C,15N Labeled potassium cyanide
13C,15N Labeled KCN Potassium cyanide-13C,15N MFCD00084051 |
| 熔点 | >300ºC(lit.) |
|---|---|
| 分子式 | CKN |
| 分子量 | 67.10180 |
| 精确质量 | 66.96720 |
| PSA | 23.79000 |
| LogP | 0.01678 |
| 计算化学 | 1.疏水参数计算参考值（XlogP）:无 2.氢键供体数量:0 3.氢键受体数量:2 4.可旋转化学键数量:0 5.互变异构体数量:无 6.拓扑分子极性表面积23.8 7.重原子数量:3 8.表面电荷:0 9.复杂度:12.8 10.同位素原子数量:2 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:2 |
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SECTION 1: Identification of the substance/mixture and of the company/undertaking Product identifiers Product name: Potassium cyanide-13C,15N REACH No.: A registration number is not available for this substance as the substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline.
CAS-No.: 74889-51-3 Relevant identified uses of the substance or mixture and uses advised against Identified uses: Laboratory chemicals, Manufacture of substances SECTION 2: Hazards identification Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Acute toxicity, Inhalation (Category 2), H330 Acute toxicity, Dermal (Category 1), H310 Acute toxicity, Oral (Category 2), H300 Acute aquatic toxicity (Category 1), H400 Chronic aquatic toxicity (Category 1), H410 For the full text of the H-Statements mentioned in this Section, see Section 16. Classification according to EU Directives 67/548/EEC or 1999/45/EC T+ Very toxicR26/27/28 R32 N Dangerous for theR50/53 environment For the full text of the R-phrases mentioned in this Section, see Section 16. Label elements Labelling according Regulation (EC) No 1272/2008 Pictogram Signal wordDanger Hazard statement(s) H300Fatal if swallowed. H310Fatal in contact with skin. H330Fatal if inhaled. H410Very toxic to aquatic life with long lasting effects. Precautionary statement(s) P260Do not breathe dust/ fume/ gas/ mist/ vapours/ spray. P264Wash hands thoroughly after handling. P273Avoid release to the environment. P280Wear protective gloves/ protective clothing. P284Wear respiratory protection. P301 + P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/ physician. Supplemental Hazard information (EU) EUH032Contact with acids liberates very toxic gas. Other hazards - none SECTION 3: Composition/information on ingredients Substances Formula: 13CK15N Molecular Weight: 67,10 g/mol CAS-No.: 74889-51-3 Hazardous ingredients according to Regulation (EC) No 1272/2008 ComponentClassificationConcentration Potassium cyanide-13C,15N CAS-No.74889-51-3Acute Tox. 2; Acute Tox. 1;<= 100 % Aquatic Acute 1; Aquatic Chronic 1; H300 + H310 + H330, H410, EUH032 Hazardous ingredients according to Directive 1999/45/EC ComponentClassificationConcentration Potassium cyanide-13C,15N CAS-No.74889-51-3T+, N, R26/27/28 - R32 -<= 100 % R50/53 For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16 SECTION 4: First aid measures Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Take off contaminated clothing and shoes immediately. Wash off with soap and plenty of water. Take victim immediately to hospital. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section 11 Indication of any immediate medical attention and special treatment needed no data available SECTION 5: Firefighting measures Extinguishing media Suitable extinguishing media Dry powder Special hazards arising from the substance or mixture no data available Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. Further information no data available SECTION 6: Accidental release measures Personal precautions, protective equipment and emergency procedures Wear respiratory protection. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8. Environmental precautions Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up Pick up and arrange disposal without creating dust. Sweep up and shovel. Do not flush with water. Keep in suitable, closed containers for disposal. Reference to other sections For disposal see section 13. SECTION 7: Handling and storage Precautions for safe handling Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2. Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store under inert gas. hygroscopic Never allow product to get in contact with water during storage. Do not store near acids. Air, light, and moisture sensitive. Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated SECTION 8: Exposure controls/personal protection Control parameters Components with workplace control parameters Exposure controls Appropriate engineering controls Avoid contact with skin, eyes and clothing. Wash hands before breaks and immediately after handling the product. Personal protective equipment Eye/face protection Face shield and safety glasses Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Full contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Z677272, Size M) Splash contact Material: Nitrile rubber Minimum layer thickness: 0,11 mm Break through time: 480 min Material tested:Dermatril® (KCL 740 / Z677272, Size M) data source: KCL GmbH, D-36124 Eichenzell, phone +49 (0)6659 87300, test method: EN374 If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. SECTION 9: Physical and chemical properties Information on basic physical and chemical properties a) AppearanceForm: solid b) Odourno data available c) Odour Thresholdno data available d) pH11,5 at 20 g/l at 20 °C e) Melting point/freezingMelting point/range: > 300 °C - lit. point f) Initial boiling point and 1.625 °C boiling range g) Flash pointno data available h) Evapouration rateno data available i) Flammability (solid, gas) no data available j) Upper/lowerno data available flammability or explosive limits k) Vapour pressureno data available l) Vapour densityno data available m) Relative density1,520 g/cm3 n) Water solubilityno data available o) Partition coefficient: n- log Pow: 0,44 octanol/water p) Auto-ignitionno data available temperature q) Decompositionno data available temperature r) Viscosityno data available s) Explosive propertiesno data available t) Oxidizing propertiesno data available Other safety information no data available SECTION 10: Stability and reactivity Reactivity no data available Chemical stability Light. Stable under recommended storage conditions. Possibility of hazardous reactions no data available Conditions to avoid no data available Incompatible materials Acids, Strong oxidizing agents, Iodine, permanganates, e.g. potassium permanganate, Peroxides, Metallic salts, Chloral hydrate, Alkaloids, Chlorates Hazardous decomposition products Other decomposition products - no data available In the event of fire: see section 5 SECTION 11: Toxicological information Information on toxicological effects Acute toxicity LDLO Oral - Human - 2,857 mg/kg LD50 Oral - mouse - 8,5 mg/kg LD50 Oral - rabbit - 5 mg/kg LD50 Oral - rat - 6 mg/kg Inhalation: no data available Dermal: no data available LD50 Intraperitoneal - rat - 4 mg/kg Remarks: Lungs, Thorax, or Respiration:Other changes. LD50 Subcutaneous - rat - 7,814 mg/kg LD50 Intravenous - rat - 3,6 mg/kg Remarks: Behavioral:Altered sleep time (including change in righting reflex). Behavioral:Convulsions or effect on seizure threshold. Lungs, Thorax, or Respiration:Dyspnea. Skin corrosion/irritation no data available Serious eye damage/eye irritation no data available Respiratory or skin sensitisation no data available Germ cell mutagenicity no data available Carcinogenicity IARC:No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Reproductive toxicity no data available Specific target organ toxicity - single exposure no data available Specific target organ toxicity - repeated exposure no data available Aspiration hazard no data available Additional Information RTECS: Not available Material is extremely destructive to tissue of the mucous membranes and upper respiratory tract, eyes, and skin., spasm, inflammation and edema of the larynx, spasm, inflammation and edema of the bronchi, pneumonitis, pulmonary edema, burning sensation, Cough, wheezing, laryngitis, Shortness of breath, Headache, Nausea, Vomiting, Lung irritation, Cyanosis, Central nervous system depression, To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. SECTION 12: Ecological information Toxicity Toxicity to fishLC50 - Oncorhynchus mykiss (rainbow trout) - 0,052 mg/l - 96,0 h LC50 - Lepomis macrochirus - 0,45 mg/l - 96,0 h Toxicity to daphnia and EC50 - Daphnia magna (Water flea) - 2 mg/l - 48 h other aquatic invertebrates EC50 - Daphnia magna (Water flea) - 0,53 mg/l - 24 h EC50 - Daphnia magna (Water flea) - 2 mg/l - 48 h EC50 - Daphnia magna (Water flea) - 0,53 mg/l - 24 h Toxicity to algaeIC50 - Scenedesmus quadricauda (Green algae) - 0,03 mg/l - 192 h Toxicity to bacteria- Bacteria - 0,6 - 2,3 mg/l - 0,5 h Persistence and degradability no data available Chemical Oxygen< 1 mg/g Demand (COD) Bioaccumulative potential BioaccumulationOncorhynchus mykiss (rainbow trout) - 16 Weeks - 20,8 µg/l Bioconcentration factor (BCF): 170 Mobility in soil no data available Results of PBT and vPvB assessment PBT/vPvB assessment not available as chemical safety assessment not required/not conducted Other adverse effects Very toxic to aquatic life with long lasting effects. SECTION 13: Disposal considerations Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. Contaminated packaging Dispose of as unused product. SECTION 14: Transport information UN number ADR/RID: 1680IMDG: 1680IATA: 1680 UN proper shipping name ADR/RID: POTASSIUM CYANIDE, SOLID IMDG: POTASSIUM CYANIDE, SOLID IATA:Potassium cyanide, solid Transport hazard class(es) ADR/RID: 6.1IMDG: 6.1IATA: 6.1 Packaging group ADR/RID: IIMDG: IIATA: I Environmental hazards ADR/RID: yesIMDG Marine pollutant: yesIATA: no Special precautions for user no data available SECTION 15 - REGULATORY INFORMATION N/A SECTION 16 - ADDITIONAL INFORMATION N/A |
| 符号 |
GHS06, GHS09 |
|---|---|
| 信号词 | Danger |
| 危害声明 | H300-H310-H330-H410 |
| 补充危害声明 | Contact with acids liberates very toxic gas. |
| 警示性声明 | P260-P264-P273-P280-P284-P301 + P310 |
| 危害码 (欧洲) | T+: Very toxic; |
| 风险声明 (欧洲) | 26/27/28-32-34-51/53 |
| 安全声明 (欧洲) | 22-36/37/39-45-61-60 |
| 危险品运输编码 | UN 1680 6.1/PG 1 |