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| 中文名 | 麦芽糖糊精 |
|---|---|
| 英文名 | D-Glucose |
| 中文别名 | 麦芽糊精 |
| 英文别名 |
EINECS 232-940-4
MFCD00146679 Maltodextrin |
| 描述 | 麦芽糊精,葡萄糖当量16.5-19.5可用作赋形剂。药用辅料,或称药用辅料,是指除药物成分外,在制药过程中使用的其他化学物质。药用辅料一般是指药物制剂中的非活性成分,可以提高药物制剂的稳定性、溶解性和加工性。药用赋形剂还影响共同给药药物的吸收、分布、代谢和消除(ADME)过程[1]。 |
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| 相关类别 | |
| 靶点 |
Human Endogenous Metabolite |
| 参考文献 |
| 密度 | 1.6±0.1 g/cm3 |
|---|---|
| 沸点 | 527.1±50.0 °C at 760 mmHg |
| 熔点 | 240ºC (dec.) |
| 分子式 | (C6H10O5)n·xH2O |
| 分子量 | 180.156 |
| 闪点 | 286.7±26.6 °C |
| 精确质量 | 180.063385 |
| PSA | 118.22000 |
| LogP | -3.17 |
| 外观性状 | 黄色粉末 |
| 蒸汽压 | 0.0±3.1 mmHg at 25°C |
| 折射率 | 1.573 |
| 储存条件 | 密闭,阴凉干燥处保存 |
| 稳定性 | 常温常压下稳定，避免强氧化剂 |
| 水溶解性 | H2O: 0.1 g/mL hot, complete, yellow to very deep yellow |
| 更多 | 1. 性状：浅黄色粉末 2. 密度（g/mLat 25°C）：未确定 3. 相对蒸汽密度（g/mL,空气=1）：未确定 4. 熔点（ºC）：240 5. 沸点（ºC,常压）：未确定 6. 沸点（ºC,0.76mmHg）：未确定 7. 折射率（n20/D）：未确定 8. 闪点（ºC）：未确定 9. 比旋光度（º）：未确定 10. 自燃点或引燃温度（ºC）：未确定 11. 蒸气压（mmHg,20ºC）：未确定 12. 饱和蒸气压（kPa,114.4 ºC）：未确定 13. 燃烧热（KJ/mol）：未确定 14. 临界温度（ºC）：未确定 15. 临界压力（MPa）：未确定 16. 油水（辛醇/水）分配系数的对数值：未确定 17. 爆炸上限（%,V/V）：未确定 18. 爆炸下限（%,V/V）：未确定 19. 溶解性：溶于水 |
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Section 1. Chemical Product and Company Identification Maltodextrin Common Name/ Trade Name Manufacturer Commercial Name(s) Synonym
Chemical Name Chemical Family Maltodextrin Section 4. First Aid Measures Eye ContactCheck for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention if irritation occurs. Skin ContactWash with soap and water. Cover the irritated skin with an emollient. Get medical attention if irritation develops. Cold water may be used. Serious Skin ContactNot available. InhalationIf inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention. Serious InhalationNot available. IngestionDo NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband. Serious IngestionNot available. Section 5. Fire and Explosion Data Flammability of the Product May be combustible at high temperature. Auto-Ignition Temperature Not available. Flash PointsNot available. Flammable LimitsNot available. Products of CombustionThese products are carbon oxides (CO, CO2). Fire Hazards in Presence of Slightly flammable to flammable in presence of heat. Various Substances Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available. of Various SubstancesRisks of explosion of the product in presence of static discharge: Not available. Fire Fighting MediaSMALL FIRE: Use DRY chemical powder. and InstructionsLARGE FIRE: Use water spray, fog or foam. Do not use water jet. Special Remarks onAs with most organic solids, fire is possible at elevated temperatures Material in powder form, capable of Fire Hazardscreating a dust explosion. Special Remarks on Explosion Fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential Hazardsdust explosion hazard. Section 6. Accidental Release Measures Small SpillUse appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements. Large SpillUse a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate through the sanitary system. Be careful that the product is not present at a concentration level above TLV. Check TLV on the MSDS and with local authorities. Maltodextrin Section 7. Handling and Storage PrecautionsKeep away from heat. Keep away from sources of ignition. Ground all equipment containing material. Do not breathe dust. Keep away from incompatibles such as oxidizing agents. StorageKeep container tightly closed. Keep container in a cool, well-ventilated area. Section 8. Exposure Controls/Personal Protection Engineering ControlsUse process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit. Personal ProtectionSafety glasses. Lab coat. Dust respirator. Use a dust respirator if ventilation is inadequate or handling of material creates visible dust clouds, and airborne concentrations exceed the recommended exposure limits. Be sure to use an approved/certified respirator or equivalent. Gloves. Personal Protection in Case of Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be a Large Spillused to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product. Exposure LimitsFor Particulates Not Otherwise Specified: TWA: 10 (mg/m3) from ACGIH (TLV) [United States] TWA: 15 (mg/m3) from OSHA (PEL) [United States] Consult local authorities for acceptable exposure limits. Section 9. Physical and Chemical Properties Physical state and appearance Solid. (Powdered solid. Granular solid.)Odorless. Odor TasteNot available. Molecular WeightNot available. ColorWhite. pH (1% soln/water)Not available. Boiling PointNot available. Melting Point240°C (464°F) Critical TemperatureNot available. Specific GravityNot available. Vapor PressureNot applicable. Not available. Vapor Density VolatilityNot available. Odor ThresholdNot available. Water/Oil Dist. Coeff.Not available. Ionicity (in Water)Not available. See solubility in water. Dispersion Properties SolubilityEasily soluble in cold water, hot water. Section 10. Stability and Reactivity Data StabilityThe product is stable. Instability TemperatureNot available. Conditions of InstabilityExcess heat, incompatible materials, dust generation. Reactive with oxidizing agents. Incompatibility with various substances CorrosivityNon-corrosive in presence of glass. Maltodextrin Special Remarks onNot available. Reactivity Special Remarks onNot available. Corrosivity PolymerizationWill not occur. Section 11. Toxicological Information Routes of EntryInhalation. Ingestion. Toxicity to AnimalsLD50: Not available. LC50: Not available. Chronic Effects on Humans Not available. Other Toxic Effects onSlightly hazardous in case of skin contact (irritant), of ingestion, of inhalation. Humans Special Remarks onNot available. Toxicity to Animals Special Remarks onNot available. Chronic Effects on Humans Special Remarks on otherAcute Potential Health Effects: Toxic Effects on HumansSkin: Low hazard. May cause skin irritation by mechanical action. Eyes: Low hazard. Dust may cause eye irritation by mechanical action. Inhalation: Low hazard. Inhalation of dust may cause respiratory tract irritation by mechanical action. Ingestion: Expected low hazard. Section 12. Ecological Information EcotoxicityNot available. BOD5 and CODNot available. Possibly hazardous short term degradation products are not likely. However, long term degradation products Products of Biodegradation may arise. Toxicity of the ProductsThe product itself and its products of degradation are not toxic. of Biodegradation Not available. Special Remarks on the Products of Biodegradation Section 13. Disposal Considerations Waste DisposalWaste must be disposed of in accordance with federal, state and local environmental control regulations. Section 14. Transport Information DOT ClassificationNot a DOT controlled material (United States). IdentificationNot applicable. Special Provisions forNot applicable. Transport DOT (Pictograms) Maltodextrin Section 15. Other Regulatory Information and Pictograms TSCA 8(b) inventory: Maltodextrin Federal and State FDA: Direct Food Additives- GRAS list (21CFR 184) Regulations CaliforniaCalifornia prop. 65: This product contains the following ingredients for which the State of California has Proposition 65found to cause cancer which would require a warning under the statute: No products were found. Warnings California prop. 65: This product contains the following ingredients for which the State of California has found to cause birth defects which would require a warning under the statute: No products were found. Other RegulationsEINECS: This product is on the European Inventory of Existing Commercial Chemical Substances (EINECS No. 232-940-4). Canada: Listed on Canadian Domestic Substance List (DSL). China: Listed on National Inventory. Japan: Listed on National Inventory (ENCS). Korea: Listed on National Inventory (KECI). Philippines: Listed on National Inventory (PICCS). Australia: Listed on AICS. WHMIS (Canada) Not controlled under WHMIS (Canada). Other Classifications DSCL (EEC)This product is not classifiedNot applicable. according to the EU regulations. Health Hazard HMIS (U.S.A.)1 National Fire Protection 1 Flammability 1 Association (U.S.A.) Fire Hazard 1 0 Reactivity Health Reactivity 0 Specific hazard Personal Protection E WHMIS (Canada) (Pictograms) DSCL (Europe) (Pictograms) TDG (Canada) (Pictograms) ADR (Europe) (Pictograms) Protective Equipment Gloves. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Maltodextrin SECTION 16 - ADDITIONAL INFORMATION N/A |
| 个人防护装备 | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| 安全声明 (欧洲) | S24/25 |
| 危险品运输编码 | NONH for all modes of transport |
| WGK德国 | 3 |
| RTECS号 | HH9450000 |
| 海关编码 | 3505100000 |
| 海关编码 | 3505100000 |
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