260413-62-5

• 常用中文名：女贞苷
• 常用英文名：Ligustroflavone
• CAS号：260413-62-5
• 分子式：C₃₃H₄₀O₁₈
• 分子量：724.66
• 相关类别： 生物化工 植物提取物
• 发布时间：2018-05-24 08:00:00
• 更新时间：2026-07-12 20:24:08
• Ligustroflavone 可从Ligustrum lucidum 中提取得到,是一种潜在的钙敏感受体(CaSR) 拮抗剂。Ligustroflavone对糖尿病性骨质疏松症小鼠有保护作用。

名称

• 中文名: 女贞苷
• 英文名: 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 6-deoxy-α-L-mannopyranosyl-(1->2)-[6-deoxy-α-L-mannopyranosyl-(1->6)]-β-D-glucopyranoside
• 中文别名: 7-(((2S,3R,4S,5S,6R)-4,5-二羟基-3-(((2S,3R,4R,5R,6S)-3,4,5-三羟基-6-甲基四氢-2H-吡喃-2-基)氧基)-6-((((2R,3R,4R,5R,6S)-3,4,5-三羟基-6-甲基四氢-2H-吡喃-2-基)氧基)甲基)四氢-2H-吡喃-2-基)氧基)-5-羟基-2-(4-羟基苯基)-4H-苯并吡喃-4-酮; 女贞苷/环烯醚萜类; 女贞苷Ligustroflavone; 女贞苷对照品; 女贞苷,10 MM DMSO 溶液; 女贞苷, 来源于女贞; 女贞苷(标准品); LIGUSTROFLAVONE 女贞苷; 女贞苷(分析标准品); 女贞苷 Solbio/索莱宝 IL0480
• 英文别名: 6)]-β-D-glucopyranoside; Ligustroflavone, 10 mM in DMSO; 4H-1-Benzopyran-4-one, 7-[(O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→6)]-β-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl); Nuezhenoside; 7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-3-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-5-hydroxy-2-(4-hydroxyphenyl)chromen-4-one; 2)-[6-deoxy-α-L-mannopyranosyl-(1->; ligustroflavone; 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 6-deoxy-α-L-mannopyranosyl-(1-)-[6-deoxy-α-L-mannopyranosyl-(1-)]-β-D-glucopyranoside; 5-Hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 6-deoxy-α-L-mannopyranosyl-(1->; 7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-((((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-2-yl)oxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one; Ligustroflavone from Ligustrum lucidum W.T.Aiton; Ligustroflavone(Nuezhenoside); Ligustroflavone 260-5; 7-[(O-6-Deoxy-alpha-L-mannopyranosyl-(1-)-O-[6-deoxy-alpha-L-mannopyranosyl-(1-)]-beta-D-glucopyranosyl)oxy]-5-hydroxy-2-(4-hydroxyphenyl)- 4H-1-benzopyran-4-one

物化性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 1028.5±65.0 °C at 760 mmHg
• 分子式: C₃₃H₄₀O₁₈
• 分子量: 724.66
• 闪点: 325.2±27.8 °C
• 精确质量: 724.221436
• PSA: 287.89000
• LogP: 1.56
• 蒸汽压: 0.0±0.3 mmHg at 25°C
• 折射率: 1.714
• 储存条件: 室温

生物活性

• 描述: Ligustroflavone 可从Ligustrum lucidum 中提取得到,是一种潜在的钙敏感受体(CaSR) 拮抗剂。Ligustroflavone对糖尿病性骨质疏松症小鼠有保护作用。
• 相关类别:
  研究领域 >> 代谢疾病
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> CaSR的
• 靶点:

  CaSR[1].

• 参考文献:

  [1]. Feng R, et al. Protective Effects of Ligustroflavone, an Active Compound from Ligustrum lucidum, on Diabetes-Induced Osteoporosis in Mice: A Potential Candidate as Calcium-Sensing Receptor Antagonist. Am J Chin Med. 2019;47(2):457-476.

安全

• 安全声明 (欧洲): 24/25