38517-23-6

• 常用中文名：硬脂酰谷氨酸钠
• 常用英文名：sodium hydrogen N-(1-oxooctadecyl)-L-glutamate
• CAS号：38517-23-6
• 分子式：C₂₃H₄₁NNaO₅
• 分子量：434.56500
• 相关类别： 生物化工 氨基酸及其衍生物 谷氨酸类衍生物
• 发布时间：2018-07-21 08:04:09
• 更新时间：2026-07-09 17:41:40
• 硬脂酰谷氨酸钠(硬脂酰谷氨酸钠)是一种阴离子乳化剂,可用作化妆品的成分。硬脂酰谷氨酸钠也是一种阴离子表面活性剂和氨基酸烷基酰胺敏化剂,可能导致过敏性接触性皮炎[1][2][3]。

名称

• 中文名: 硬脂酰谷氨酸钠
• 英文名: sodium,(4S)-5-hydroxy-4-(octadecanoylamino)-5-oxopentanoate
• 中文别名: 硬脂酰氨酸钠; 钠硬脂酰谷氨酸钠; N-(1-氧代十八烷基)-L-谷氨酸单钠盐(9CI); 硬脂酰谷氨酸钠(粉末); (S)-2-十八酰胺基戊二酸单钠盐; 硬脂酰谷氨酸钠 38-6
• 英文别名: Steoyl glutamic acid sodium; Eumulgin SG; Sodium Steoyl Glutamate(SGA）; Sodium N-steoylglutamate; sodium hydrogen N-(1-oxooctadecyl)-L-glutamate //BP; Amisoft HS 11P; N-(1-Oxooctadecyl)-L-glutamic acid,monosodium salt; n-(1-oxooctadecyl)-l-glutamic aci monosodium salt; Acylglutamate HS 11; Pectinase 9-1; N-Steoyl-L-glutamic acid sodium salt; N-(1-oxooctadecyl)-L-Glutamic acid monosodium salt; L-Glutamic acid,N-(1-oxooctadecyl)-,monosodium salt(9CI); Sodium Oxooctadecyl Glutamate; (S)-2-Steamidopentanedioic acid monosodium salt; L-Glutamic acid,N-(1-oxooctadecyl)-,sodium salt (1:1); L-Glutamic acid, N-(1-oxooctadecyl)-, monosodium salt; L-Glutamic acid,N-(1-oxooctadecyl)-,monosodium salt; Sodium hydrogen N-(1-oxooctadecyl)-L-glutamate; Monosodium N-steoylglutamate; sodiumn-steoyll-glutamate,sodiumsteoylglutamate; Sodium N-Steoyl L-Glutamate; odium hydrogen N-(1-oxooctadecyl)-L-glutamate; AmisoftHS 11; sodium n-steoyl l-glutamate,sodium steoyl glutamate; N-Steoyl-L-glutamic acid monosodium salt; L-Glutamic acid, N-(1-oxooctadecyl)-, sodium salt; EINECS 253-980-9; L-Glutamic acid, N-(1-oxooctadecyl)-, monosodium salt(9CI); Monosodium N-steoyl-L-glutamate; Sodium Stearoyl Glutamate (Emulsifying); L-Glutamic acid,N-(1-oxooctadecyl)-, sodium salt (1:1); Sodium N-stearoyl L-glutamate; SODIUM STEOYL GLUTAMATE

物化性质

• 沸点: 600.3ºC at 760mmHg
• 分子式: C₂₃H₄₁NNaO₅
• 分子量: 434.56500
• 闪点: 316.8ºC
• 精确质量: 434.28800
• PSA: 112.85000
• LogP: 5.06020
• 储存条件: 室温

生物活性

• 描述: 硬脂酰谷氨酸钠(硬脂酰谷氨酸钠)是一种阴离子乳化剂,可用作化妆品的成分。硬脂酰谷氨酸钠也是一种阴离子表面活性剂和氨基酸烷基酰胺敏化剂,可能导致过敏性接触性皮炎[1][2][3]。
• 相关类别:
  研究领域 >> 其他
• 参考文献:

  [1]. Guilherme Carneiro Leal, et al. Development, characterization, and evaluation by cutaneous bioengineering of a natural emulsion, to provide a standardized vehicle base for topical compounded preparations. Research, Society and Development, [S. l.], v.11, n.16, p.e509111638290, 2022.

  [2]. Pralong P, Dendooven E, Aerts O. Sodium stearoyl glutamate: Another amino acid alkyl amide sensitizer in cosmetics. Contact Dermatitis. 2022 Nov;87(5):453-454.

  [3]. Nazir I, Asim MH, Dizdarević A, Bernkop-Schnürch A. Self-emulsifying drug delivery systems: Impact of stability of hydrophobic ion pairs on drug release. Int J Pharm. 2019 Apr 20;561:197-205.

安全

• 危害码 (欧洲): Xi