74733-23-6

• 常用中文名：4-甲酰基-2-甲基苯甲酸甲酯
• 常用英文名：Methyl 4-formyl-2-methylbenzoate
• CAS号：74733-23-6
• 分子式：C₁₀H₁₀O₃
• 分子量：178.18500
• 发布时间：2017-06-26 07:18:46
• 更新时间：2024-01-05 23:29:09

名称

• 中文名: 4-甲酰基-2-甲基苯甲酸甲酯
• 英文名: Methyl 4-formyl-2-methylbenzoate
• 英文别名: 4-formyl-2-methyl-benzoic acid methyl ester; 4-formyl-2-methyl-1,3,4-thiadiazole-5-thione; 4-formyl-2-methyl-1,3,4-thiadiazolin-5-thione; 3-formyl-5-methyl-1,3,4-thiadiazole-2-thione

物化性质

• 分子式: C₁₀H₁₀O₃
• 分子量: 178.18500
• 精确质量: 178.06300
• PSA: 43.37000
• LogP: 1.59410
• 储存条件: 2-8°C， 惰性气体

安全

• 危害码 (欧洲): Xn

合成路线

201230-82-2 99548-55-7 ~85% 74733-23-6

文献：ELI LILLY AND COMPANY Patent: WO2007/140174 A2, 2007 ; Location in patent: Page/Page column 46 ;

103261-67-2 ~63% 74733-23-6

文献：CONSTELLATION PHARMACEUTICALS; ALBRECHT, Brian, K.; AUDIA, James, Edmund; COOK, Andrew; GAGNON, Alexandre; HARMANGE, Jean-christophe; NAVESCHUK, Christopher, G. Patent: WO2013/75083 A1, 2013 ; Location in patent: Paragraph 00467; 00470 ;

530145-28-9 ~72% 74733-23-6

文献：ELI LILLY AND COMPANY Patent: WO2007/140174 A2, 2007 ; Location in patent: Page/Page column 36 ;

99548-55-7 141-53-7 ~19% 74733-23-6

文献：Zimmerman, Sommer S.; Khatri, Alpa; Garnier-Amblard, Ethel C.; Mullasseril, Praseeda; Kurtkaya, Natalie L.; Gyoneva, Stefka; Hansen, Kasper B.; Traynelis, Stephen F.; Liotta, Dennis C. Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2334 - 2356

99548-55-7 ~% 74733-23-6

文献：CONSTELLATION PHARMACEUTICALS; ALBRECHT, Brian, K.; AUDIA, James, Edmund; COOK, Andrew; GAGNON, Alexandre; HARMANGE, Jean-christophe; NAVESCHUK, Christopher, G. Patent: WO2013/75083 A1, 2013 ;

67-56-1 503470-23-3 ~% 74733-23-6

文献：Bayer CorpScience AG Patent: US2010/179194 A1, 2010 ; Location in patent: Page/Page column 26-27 ;

68837-59-2 ~% 74733-23-6

文献：CONSTELLATION PHARMACEUTICALS; ALBRECHT, Brian, K.; AUDIA, James, Edmund; COOK, Andrew; GAGNON, Alexandre; HARMANGE, Jean-christophe; NAVESCHUK, Christopher, G. Patent: WO2013/75083 A1, 2013 ;