464213-10-3

• 常用中文名：伊必那班
• 常用英文名：(S)-SLV 319
• CAS号：464213-10-3
• 分子式：C₂₃H₂₀Cl₂N₄O₂S
• 分子量：487.401
• 发布时间：2018-09-08 16:25:06
• 更新时间：2024-01-09 19:40:21
• Ibipinabant, also known as BMS-646256, JD-5001 and SLV-319, is a potent and highly selective CB1 antagonist. It has potent anorectic effects in animals, and was researched for the treatment of obesity, although CB1 antagonists as a class have now fallen out of favour as potential anorectics following the problems seen with rimonabant, and so ibipinabant is now only used for laboratory research, especially structure-activity relationship studies into novel CB1 antagonists.

名称

• 中文名: 伊必那班
• 英文名: (4S)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
• 中文别名: (4S)-3-(4-氯苯基)-N-[(4-氯苯基)磺酰基]-4,5-二氢-N'-甲基-4-苯基-1H-吡唑-1-甲脒
• 英文别名: 1H-Pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N'-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N-methyl-4-phenyl-, (4S)-; UNII-O5CSC6WH1T; (4S)-3-(4-Chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-N'-methyl-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamide; ibipinabant; 1H-pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-, (4S)-

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 623.2±65.0 °C at 760 mmHg
• 分子式: C₂₃H₂₀Cl₂N₄O₂S
• 分子量: 487.401
• 闪点: 330.7±34.3 °C
• 精确质量: 486.068390
• PSA: 82.51000
• LogP: 4.67
• 蒸汽压: 0.0±1.8 mmHg at 25°C
• 折射率: 1.663