3′-Omethyl-5′-hydroxydiplacone

• 常用名: 3′-Omethyl-5′-hydroxydiplacone
• 英文名: 3′-Omethyl-5′-hydroxydiplacone
• CAS号: 1005517-26-9
• 分子量: 454.51
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₃₀O₇
• 熔点: N/A
• 闪点: N/A

用途

3′-二甲基-5′-羟基二月桂酮(化合物2)是一种C-6-香叶基黄酮,可从泡桐果实的乙醇提取物中分离得到。3′-二甲基-5′-羟基二聚拉酮对革兰氏阳性菌具有抗菌活性[1]。

名称

• 英文名: 3′-Omethyl-5′-hydroxydiplacone

生物活性

• 描述: 3′-二甲基-5′-羟基二月桂酮(化合物2)是一种C-6-香叶基黄酮,可从泡桐果实的乙醇提取物中分离得到。3′-二甲基-5′-羟基二聚拉酮对革兰氏阳性菌具有抗菌活性[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Smejkal K, et al. Antibacterial C-geranylflavonoids from Paulownia tomentosa Fruits. J Nat Prod. 2008 Apr;71(4):706-9.

物理化学性质

• 分子式: C₂₆H₃₀O₇
• 分子量: 454.51
• InChIKey: UKCODVXNYJFPIN-OMKLEDIQSA-N
• SMILES: COc1cc(C2CC(=O)c3c(cc(O)c(CC=C(C)CCC=C(C)C)c3O)O2)cc(O)c1O

靶点实验

查看更多实验

实验名称：Potency index, ratio of IC50 for zileuton to IC50 for test compound fior inhibition o... 来源：ChEMBL 靶标：Polyunsaturated fatty acid 5-lipoxygenase External Id：CHEMBL4270864

实验名称：Inhibition of human recombinant 5-LOX assessed as reduction in leukotriene B4 product... 来源：ChEMBL 靶标：Polyunsaturated fatty acid 5-lipoxygenase External Id：CHEMBL4270863

实验名称：Antibacterial activity against Staphylococcus aureus ATCC 25923 after 24 hrs by broth... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL969474

实验名称：Cytotoxicity against human RPMI8226 cells assessed as viable cells after 72 hrs by ca... 来源：ChEMBL 靶标：RPMI-8226 External Id：CHEMBL1107366

实验名称：Antibacterial activity against Listeria monocytogenes ATCC 7644 after 24 hrs by broth... 来源：ChEMBL 靶标：Listeria monocytogenes External Id：CHEMBL969473

实验名称：Cytotoxicity against human CEM cells assessed as viable cells after 72 hrs by calcein... 来源：ChEMBL 靶标：CCRF-CEM External Id：CHEMBL1107365

实验名称：Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by broth micr... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL969476

实验名称：Cytotoxicity against human MCF7 cells assessed as viable cells after 72 hrs by calcei... 来源：ChEMBL 靶标：MCF7 External Id：CHEMBL1107364

实验名称：Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 24 hrs by ... 来源：ChEMBL 靶标：Staphylococcus epidermidis External Id：CHEMBL969475

实验名称：Antibacterial activity against Bacillus cereus ATCC 11778 after 24 hrs by broth micro... 来源：ChEMBL 靶标：Bacillus cereus External Id：CHEMBL969470

共24条，当前第1页，共3页

1

2

3