单甲基硫赭曲菌素

• 常用名: 单甲基硫赭曲菌素
• 英文名: Monomethylsulochrin
• CAS号: 10056-14-1
• 分子量: 346.33100
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₈O₇
• 熔点: N/A
• 闪点: N/A

单甲基硫赭曲菌素用途

一甲基磺酰氯是内生真菌烟曲霉(Aspergillus fumigatus)的有效抗菌代谢产物,从绿合欢(Albizia lucidior)叶子(蚕豆科)中分离得到。一甲基磺酰氯具有抗金黄色葡萄球菌活性,最小抑制浓度(MIC)为31.25μg/mL[1]。

单甲基硫赭曲菌素名称

• 中文名: 单甲基硫赭曲菌素
• 英文名: 1,2-seco-trypacidin

单甲基硫赭曲菌素生物活性

• 描述: 一甲基磺酰氯是内生真菌烟曲霉(Aspergillus fumigatus)的有效抗菌代谢产物,从绿合欢(Albizia lucidior)叶子(蚕豆科)中分离得到。一甲基磺酰氯具有抗金黄色葡萄球菌活性,最小抑制浓度(MIC)为31.25μg/mL[1]。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> 细菌
• 参考文献:

  [1]. Mai E Hussein, et al. Identification of Antibacterial Metabolites from Endophytic Fungus Aspergillus fumigatus, Isolated from Albizia lucidior Leaves (Fabaceae), Utilizing Metabolomic and Molecular Docking Techniques. Molecules. 2022 Feb 8;2

单甲基硫赭曲菌素物理化学性质

• 分子式: C₁₈H₁₈O₇
• 分子量: 346.33100
• 精确质量: 346.10500
• PSA: 102.29000
• LogP: 2.44100
• InChIKey: XJOBKBUGVMLSEJ-UHFFFAOYSA-N
• SMILES: COC(=O)c1cc(O)cc(OC)c1C(=O)c1c(O)cc(C)cc1OC
• 外观性状: 粉末
• 储存条件: 室温

单甲基硫赭曲菌素靶点实验

查看更多实验

实验名称：Antioxidant activity assessed as AAPH radical scavenging activity at 12.5 uM ORAC ass... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5138319

实验名称：Cytoprotective activity against H2O2-induced oxidative injury in rat PC-12 cells asse... 来源：ChEMBL 靶标：PC-12 External Id：CHEMBL5138320

实验名称：Antidiabetic nephropathic activity in rat HBZY-1 cells assessed as inhibition of high... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2400237

实验名称：Antidiabetic nephropathic activity in rat HBZY-1 cells assessed as inhibition of high... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2400236

实验名称：Inhibitory activity against eosinophil degranulation 来源：ChEMBL 靶标：N/A External Id：CHEMBL677514

实验名称：Antidiabetic nephropathic activity in rat HBZY-1 cells assessed as inhibition of high... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2400240

实验名称：Antioxidant activity assessed as DPPH radical scavenging activity incubated for 30 mi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5138318

实验名称：Cytotoxicity against rat HBZY-1 cells assessed as cell viability at 10 uM after 48 hr... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2400235

实验名称：Protection against AfB1-induced toxicity in human HepG2 cells assessed as live cell a... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4393567

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单甲基硫赭曲菌素英文别名

• monomethylsulochrin
• monomethylsulocrin
• Monomethylsulochrin
• 5-Hydroxy-2-(2-hydroxy-6-methoxy-4-methyl-benzoyl)-3-methoxy-benzoic acid methyl ester
• Monomethylsulochin
• methylsulochrin