Sitamaquine tosylate

• 常用名: Sitamaquine tosylate
• 英文名: Sitamaquine tosylate
• CAS号: 1019640-33-5
• 分子量: 515.70800
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₈H₄₁N₃O₄S
• 熔点: N/A
• 闪点: N/A

Sitamaquine tosylate用途

Sitamaquine (WR 6026) tosylate 是一种具有口服活性 8-aminoquinoline 类似物,是一种抗利什曼病药物。Sitamaquine tosylate 是一种嗜脂性弱碱,在利什曼原虫的酸性区迅速积聚,主要集中在酸钙小体中。

Sitamaquine tosylate名称

• 英文名: N,N-Diethyl-N'-(6-methoxy-4-methyl-8-quinolinyl)-1,6-hexanediamin e 4-methylbenzenesulfonate (1:1)

Sitamaquine tosylate生物活性

• 描述: Sitamaquine (WR 6026) tosylate 是一种具有口服活性 8-aminoquinoline 类似物,是一种抗利什曼病药物。Sitamaquine tosylate 是一种嗜脂性弱碱,在利什曼原虫的酸性区迅速积聚,主要集中在酸钙小体中。
• 相关类别:
  研究领域 >> 感染
• 参考文献:

  [1]. López-Martín C, et al. Sitamaquine sensitivity in Leishmania species is not mediated by drug accumulation in acidocalcisomes. Antimicrob Agents Chemother. 2008;52(11):4030-4036.

Sitamaquine tosylate物理化学性质

• 分子式: C₂₈H₄₁N₃O₄S
• 分子量: 515.70800
• 精确质量: 515.28200
• PSA: 100.14000
• LogP: 7.26140
• InChIKey: LOBPWLFCZDGYKW-UHFFFAOYSA-N
• SMILES: CCN(CC)CCCCCCNc1cc(OC)cc2c(C)ccnc12.Cc1ccc(S(=O)(=O)O)cc1

Sitamaquine tosylate安全信息

• 危险品运输编码: NONH for all modes of transport

Sitamaquine tosylate靶点实验

查看更多实验

实验名称：Antibacterial activity against Acinetobacter baumannii ATCC 19606 (CO-ADD:GN_034); MI... 来源：ChEMBL 靶标：Acinetobacter baumannii External Id：CHEMBL4296188

实验名称：Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 (CO-ADD:GN_042); MIC... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL4296187

实验名称：Antifungal activity against Cryptococcus neoformans H99 ATCC 208821 (CO-ADD:FG_002); ... 来源：ChEMBL 靶标：Cryptococcus neoformans External Id：CHEMBL4296190

实验名称：Antifungal activity against Candida albicans ATCC 90028 (CO-ADD:FG_001); MIC in YNB m... 来源：ChEMBL 靶标：Candida albicans External Id：CHEMBL4296189

实验名称：Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4296184

实验名称：Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL4296186

实验名称：Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CA... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL4296185

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Sitamaquine tosylate英文别名

• Sitagliptin phosphate hydrate
• (2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine dihydrogenphosphate monohydrate
• Sitagliptin phosphate hydrate (jan)
• Sitagliptin monohydrate
• sitamaquine tosylate
• 3(R)-3-amino-1-[3-(trifluoromethyl)-5H,6H,7H,8H [1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one phosphate monohydrate
• Sitagliptin phosphate (usan)
• N,N-diethyl-N'-[4-methyl-6-(methyloxy)-8-quinolinyl]-1,6-hexanediamine tosylate
• Januvia (tn)
• Sitagliptin phosphate for research
• 7-[(3R)-3-Amino-1-oxo-4-(2,4,5-trifluorophenyl)Butyl]-5,6,7,8-tetrahydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazinephosphatemonohydrate