RJR 2429 dihydrochloride

• 常用名: RJR 2429 dihydrochloride
• 英文名: RJR 2429 dihydrochloride
• CAS号: 1021418-53-0
• 分子量: 261.191
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₂H₁₈Cl₂N₂
• 熔点: N/A
• 闪点: N/A

RJR 2429 dihydrochloride用途

RJR 2429盐酸盐是一种α4β2和α7 nAChR激动剂[1]。

RJR 2429 dihydrochloride名称

• 英文名: RJR 2429 (hydrochloride)

RJR 2429 dihydrochloride生物活性

• 描述: RJR 2429盐酸盐是一种α4β2和α7 nAChR激动剂[1]。
• 相关类别:
  信号通路 >> 跨膜转运 >> 胆碱受体
  信号通路 >> 神经信号通路 >> 胆碱受体
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Bhatti BS, et al. Synthesis of 2-(pyridin-3-yl)-1-azabicyclo[3.2.2]nonane, 2-(pyridin-3-yl)-1-azabicyclo[2.2.2]octane, and 2-(pyridin-3-yl)-1-azabicyclo[3.2.1]octane, a class of potent nicotinic acetylcholine receptor-ligands. J Org Chem. 2008 May 2;73(9):3497-507.

RJR 2429 dihydrochloride物理化学性质

• 分子式: C₁₂H₁₈Cl₂N₂
• 分子量: 261.191
• 精确质量: 260.084717
• InChIKey: PIUNXHHZRIUBOV-UHFFFAOYSA-N
• SMILES: Cl.Cl.c1cncc(C2CC3CCN2CC3)c1

RJR 2429 dihydrochloride靶点实验

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实验名称：Selectivity ratio, ratio of EC50 for alpha3beta4* nAChR in mouse to EC50 for alpha4be... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1785125

实验名称：Selectivity ratio, ratio of EC50 for alpha3beta4* nAChR in mouse to EC50 for alpha6be... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1785126

实验名称：Activity at alpha4beta2*nAChR in mouse striatal synaptosomes assessed as alpha-conoto... 来源：ChEMBL 靶标：Neuronal acetylcholine receptor subunit beta-2 External Id：CHEMBL1785678

实验名称：Activity at alpha6alpha4beta3beta2 nAChR in mouse striatal synaptosomes assessed as a... 来源：ChEMBL 靶标：Neuronal acetylcholine receptor subunit beta-2 External Id：CHEMBL1785680

实验名称：Activity at alpha3beta4* nAChR in mouse interpeduncular nucleus assessed as [3H]ACh r... 来源：ChEMBL 靶标：Neuronal acetylcholine receptor subunit alpha-3 External Id：CHEMBL1785683

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RJR 2429 dihydrochloride英文别名

• 2-(Pyridin-3-yl)quinuclidine dihydrochloride
• RJR 2429 (hydrochloride)
• 1-Azabicyclo[2.2.2]octane, 2-(3-pyridinyl)-, hydrochloride (1:2)
• 2-(3-Pyridinyl)quinuclidine dihydrochloride