兰索拉唑硫醚结构式
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常用名 | 兰索拉唑硫醚 | 英文名 | Lansoprazole Sulfide |
|---|---|---|---|---|
| CAS号 | 103577-40-8 | 分子量 | 353.362 | |
| 密度 | 1.4±0.1 g/cm3 | 沸点 | 494.9±55.0 °C at 760 mmHg | |
| 分子式 | C16H14F3N3OS | 熔点 | 149-150ºC | |
| MSDS | N/A | 闪点 | 253.1±31.5 °C |
兰索拉唑硫醚用途Lansoprazole sulfide is an impurity of Lansoprazole -- a gastric pump inhibitor. |
| 中文名 | 2-[[[3-甲基-4-(2,2,2三氟乙氧基)-2-吡啶]-甲基]硫基]-1H-苯并咪唑 |
|---|---|
| 英文名 | 2-(((3-Methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl)methyl)thio)-1H-benzo[d]imidazole |
| 中文别名 | 兰索拉唑中间体 | 2-3-甲基-4-(2,2,2-三氟乙氧基)-2-吡啶甲基硫基-1H-苯并咪唑 | 兰索拉唑硫醚 | 2-[-[(3-甲基-4-(2,2,2-三氟乙氧基)-2-吡啶基)甲基]巯基]苯并咪唑 | 右旋兰索拉唑杂质C | 南索拉唑杂质B | 2-[3-甲基-4-(2,2,2-三氟乙氧基)-2-吡啶]甲基硫基-1H-苯并咪 | 兰索拉唑EP杂质C | 兰索拉唑硫化物 |
| 英文别名 | 更多 |
| 密度 | 1.4±0.1 g/cm3 |
|---|---|
| 沸点 | 494.9±55.0 °C at 760 mmHg |
| 熔点 | 149-150ºC |
| 分子式 | C16H14F3N3OS |
| 分子量 | 353.362 |
| 闪点 | 253.1±31.5 °C |
| 精确质量 | 353.080963 |
| PSA | 76.10000 |
| LogP | 4.46 |
| InChIKey | CCHLMSUZHFPSFC-UHFFFAOYSA-N |
| SMILES | Cc1c(OCC(F)(F)F)ccnc1CSc1nc2ccccc2[nH]1 |
| 外观性状 | 淡黄色固体 |
| 蒸汽压 | 0.0±1.3 mmHg at 25°C |
| 折射率 | 1.616 |
| 储存条件 | -20°C Freezer |
| 危害码 (欧洲) | Xi |
|---|---|
| 危险品运输编码 | NONH for all modes of transport |
| 海关编码 | 2933990090 |
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~96%
兰索拉唑硫醚 103577-40-8 |
| 文献:Organic Process Research and Development, , vol. 17, # 10 p. 1272 - 1276 |
|
~%
兰索拉唑硫醚 103577-40-8 |
| 文献:EP1681056 A1, ; Page/Page column 9 ; |
|
~%
兰索拉唑硫醚 103577-40-8 |
| 文献:Synthetic Communications, , vol. 32, # 8 p. 1211 - 1217 |
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~%
兰索拉唑硫醚 103577-40-8 |
| 文献:Chemical and Pharmaceutical Bulletin, , vol. 38, # 10 p. 2853 - 2858 |
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~%
兰索拉唑硫醚 103577-40-8 |
| 文献:Chemical and Pharmaceutical Bulletin, , vol. 38, # 10 p. 2853 - 2858 |
| 海关编码 | 2933990090 |
|---|---|
| 中文概述 | 2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0% |
| 申报要素 | 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期 |
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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实验名称:Primary cell-based high-throughput screening assay for identification of compounds th...
来源:Johns Hopkins Ion Channel Center
靶标:regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id:JHICC_RGS_Act_HTS
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实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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实验名称:QFRET-based biochemical primary high throughput screening assay to identify exosite i...
来源:The Scripps Research Institute Molecular Screening Center
靶标:disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id:ADAM17_INH_QFRET_1536_1X%INH PRUN
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实验名称:Antitubercular activity against Mycobacterium tuberculosis H37Rv assessed as bacteria...
来源:ChEMBL
靶标:Mycobacterium tuberculosis
External Id:CHEMBL5265568
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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实验名称:uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
来源:Burnham Center for Chemical Genomics
靶标:N/A
External Id:BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
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实验名称:High throughput fluorescence intensity-based biochemical assay to screen for small mo...
来源:University of Pittsburgh Molecular Library Screening Center
靶标:furin (paired basic amino acid cleaving enzyme), isoform CRA_a [Homo sapiens]
External Id:MH080376 Biochemical HTS for Inhibitors of the Proprotein Convertase Furin.
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实验名称:Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
来源:Broad Institute
靶标:FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id:2147-01_Inhibitor_SinglePoint_HTS_Activity
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实验名称:Antibacterial activity against wild type Mycobacterium tuberculosis H37Rv assessed as...
来源:ChEMBL
靶标:Mycobacterium tuberculosis
External Id:CHEMBL5244572
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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| MFCD00834357 |
| Lansoprazole Sulfide |
| 2-[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methylthio-1H-benzimidazole |
| 2-({[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl}sulfanyl)-1H-benzimidazole |
| T56 BM DNJ CS1- BT6NJ C1 DO1XFFF |
| 2-[((3-METHYL-4-(2,2,2 TRIFLUOROETHOXY)2-PYRIDYL)METHYL)THIO)]1H BENZIMIDAZOLE |
| Lansoprazole Impurity 3 |