右旋兰索拉唑

• 常用名: 右旋兰索拉唑
• 英文名: Dexlansoprazole
• CAS号: 138530-94-6
• 分子量: 369.362
• 密度: 1.5±0.1 g/cm3
• 沸点: 555.8±60.0 °C at 760 mmHg
• 分子式: C₁₆H₁₄F₃N₃O₂S
• 熔点: 66-68?C
• 闪点: 289.9±32.9 °C

右旋兰索拉唑用途

(R)-Lansoprazole是质子泵抑制剂,能抑制胃酸生成。

右旋兰索拉唑名称

• 中文名: (R)-兰索拉唑
• 英文名: R-(+)-Lansoprazole
• 中文别名: 右旋兰索拉唑 | 右兰索拉唑

右旋兰索拉唑生物活性

• 描述: (R)-Lansoprazole是质子泵抑制剂,能抑制胃酸生成。
• 相关类别:
  信号通路 >> 跨膜转运 >> 质子泵
  研究领域 >> 炎症/免疫
• 参考文献:

  [1]. Kokufu, T., et al., Effects of lansoprazole on pharmacokinetics and metabolism of theophylline. Eur J Clin Pharmacol, 1995. 48(5): p. 391-5.

  [2]. Lai, K.C., et al., Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use. N Engl J Med, 2002. 346(26): p. 2033-8.

  [3]. Iwahi, T., et al., Lansoprazole, a novel benzimidazole proton pump inhibitor, and its related compounds have selective activity against Helicobacter pylori. Antimicrob Agents Chemother, 1991. 35(3): p. 490-6.

右旋兰索拉唑物理化学性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 555.8±60.0 °C at 760 mmHg
• 熔点: 66-68?C
• 分子式: C₁₆H₁₄F₃N₃O₂S
• 分子量: 369.362
• 闪点: 289.9±32.9 °C
• 精确质量: 369.075867
• PSA: 87.08000
• LogP: 2.76
• InChIKey: MJIHNNLFOKEZEW-RUZDIDTESA-N
• SMILES: Cc1c(OCC(F)(F)F)ccnc1CS(=O)c1nc2ccccc2[nH]1
• 外观性状: 棕色固体
• 蒸汽压: 0.0±1.5 mmHg at 25°C
• 折射率: 1.635
• 储存条件: Refrigerator

右旋兰索拉唑安全信息

• 危害码 (欧洲): Xi

右旋兰索拉唑靶点实验

查看更多实验

实验名称：Liver toxicity in human assessed as induction of drug-induced liver injury by measuri... 来源：ChEMBL 靶标：Homo sapiens External Id：CHEMBL4029349

实验名称：Liver toxicity in human assessed as induction of drug-induced liver injury by measuri... 来源：ChEMBL 靶标：Homo sapiens External Id：CHEMBL4029350

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Phenotypic Assay to Identify Small Molecules that Upregulate Production of hCFTR in H... 来源：Southern Research Institute 靶标：CFTR External Id：CF Folding

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：Antiviral activity against SARS-CoV-2 (USA-WA1/2020 strain) measured by imaging in HR... 来源：ChEMBL 靶标：Severe acute respiratory syndrome coronavirus 2 External Id：CHEMBL4303810

实验名称：Inhibition of StrepTag-tagged human SARM1 TIR (561 to 724 residues) expressed in HEK2... 来源：ChEMBL 靶标：NAD(+) hydrolase SARM1 External Id：CHEMBL4422587

实验名称：Identifying Sarm1 Tir Hydrolase inhibitors through NAD-Glo assay 来源：24386 靶标：N/A External Id：Sarm1 Tir NADase inhibitors screen

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右旋兰索拉唑英文别名

• Dexlansoprazole
• (R)-2-(3-N,N-diisopropylamino-1-phenylpropyl)-4-hydroxymethylphenoxyisobutyrate
• 2-[(R)-{[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl}sulfinyl]-1H-benzimidazole
• R-(+)-Lansoprazole
• (+)-Lansoprazole
• Dexilant
• FESO
• (R)-lansoprazole
• Kapidex
• R-lansoprazole
• Lansoprazole Impurity 14