RU-SKI 43

• 常用名: RU-SKI 43
• 英文名: RU-SKI 43
• CAS号: 1043797-53-0
• 分子量: 386.55100
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₃₀N₂O₂S
• 熔点: N/A
• 闪点: N/A

RU-SKI 43用途

RU-SKI 43是Hedgehog乙酰转移酶Hhat抑制剂。

RU-SKI 43名称

• 中文名: RU-SKI 43
• 英文名: 2-((2-methylbutyl)amino)-1-(4-((m-tolyloxy)methyl)-6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)ethan-1-one

RU-SKI 43生物活性

• 描述: RU-SKI 43是Hedgehog乙酰转移酶Hhat抑制剂。
• 相关类别:
  信号通路 >> 干细胞及 Wnt 通路 >> Hedgehog
  研究领域 >> 癌症
• 参考文献:

  [1]. Petrova E, et al. Hedgehog acyltransferase as a target in pancreatic ductal adenocarcinoma. Oncogene. 2014 Jan 27. doi: 10.1038/onc.2013.575.

RU-SKI 43物理化学性质

• 分子式: C₂₂H₃₀N₂O₂S
• 分子量: 386.55100
• 精确质量: 386.20300
• PSA: 69.81000
• LogP: 4.52580
• InChIKey: AEENEMOEBJOKGN-UHFFFAOYSA-N
• SMILES: CCC(C)CNCC(=O)N1CCc2sccc2C1COc1cccc(C)c1
• 储存条件: 2-8℃

RU-SKI 43靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f... 来源：ChEMBL 靶标：Replicase polyprotein 1ab External Id：CHEMBL4495582

实验名称：Cytochrome P450 family 3 subfamily A member 7 (CYP3A7) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A7681

实验名称：Enzymatic assay of human HDAC6 with commercial peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808149

实验名称：Enzymatic assay of human HDAC6 with custom peptide substrate 来源：ChEMBL 靶标：Histone deacetylase 6 External Id：CHEMBL4808150

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

实验名称：qHTS assay to identify novel small-molecules to repurpose for Merkel cell carcinoma t... 来源：NCGC 靶标：N/A External Id：MCC011

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RU-SKI 43英文别名

• RU-SKI 43