灵芝醇B

• 常用名: 灵芝醇B
• 英文名: Ganoderol B
• CAS号: 104700-96-1
• 分子量: 440.701
• 密度: 1.0±0.1 g/cm3
• 沸点: 552.7±50.0 °C at 760 mmHg
• 分子式: C₃₀H₄₈O₂
• 熔点: N/A
• 闪点: 226.1±24.7 °C

灵芝醇B用途

灵芝醇B是一种有效的α-葡萄糖苷酶抑制剂。灵芝醇B具有较高的α-葡萄糖苷酶抑制作用,IC50为48.5μg/mL(119.8μM)[1]。

灵芝醇B名称

• 中文名: 丹芝醇B
• 英文名: (3S,10S,13R,14R,17S)-17-[(E,2R)-7-hydroxy-6-methylhept-5-en-2-yl]-4,4,10,13,14-pentamethyl-2,3,5,6,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-3-ol
• 中文别名: 灵芝醇 B

灵芝醇B生物活性

• 描述: 灵芝醇B是一种有效的α-葡萄糖苷酶抑制剂。灵芝醇B具有较高的α-葡萄糖苷酶抑制作用,IC50为48.5μg/mL(119.8μM)[1]。
• 相关类别:
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Sri Fatmawati, et al. Ganoderol B: a potent α-glucosidase inhibitor isolated from the fruiting body of Ganoderma lucidum. Phytomedicine. 2011 Sep 15;18(12):1053-5.

灵芝醇B物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 552.7±50.0 °C at 760 mmHg
• 分子式: C₃₀H₄₈O₂
• 分子量: 440.701
• 闪点: 226.1±24.7 °C
• 精确质量: 440.365417
• PSA: 40.46000
• LogP: 8.82
• InChIKey: AOXXVRDKZLRGTJ-SAXMSOSVSA-N
• SMILES: CC(=CCCC(C)C1CCC2(C)C3=CCC4C(C)(CCC(O)C4(C)C)C3=CCC12C)CO
• 外观性状: 粉末
• 蒸汽压: 0.0±3.4 mmHg at 25°C
• 折射率: 1.551
• 储存条件: 2-8℃

灵芝醇B安全信息

• 危害码 (欧洲): Xi

灵芝醇B靶点实验

查看更多实验

实验名称：Inhibition of alpha-glucosidase (unknown origin) using sucrose as substrate assessed ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2443740

实验名称：Ratio of acarbose IC50 to compound IC50 for alpha-glucosidase (unknown origin) 来源：ChEMBL 靶标：N/A External Id：CHEMBL2443739

实验名称：Growth inhibition of human LNCaP cells in presence of dihydrotestosterone after 3 day... 来源：ChEMBL 靶标：LNCaP External Id：CHEMBL887931

实验名称：Inhibition of testosterone induced ventral prostate growth in Sprague-Dawley rat at 0... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL887932

实验名称：Inhibition of testosterone induced ventral prostate growth in Sprague-Dawley rat at 0... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL887933

实验名称：Hepatoprotective activity against H2O2-induced human HepG2 cells assessed as increase... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL5263836

实验名称：Hepatoprotective activity against H2O2-induced human HepG2 cells assessed as increase... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL5263835

实验名称：Inhibition of AChE assessed as hydrolysis of acetylcholine preincubated for 15 mins m... 来源：ChEMBL 靶标：Acetylcholinesterase External Id：CHEMBL1918466

实验名称：Inhibition of BChE assessed as hydrolysis of butrylcholine preincubated for 15 mins m... 来源：ChEMBL 靶标：Cholinesterase External Id：CHEMBL1918467

实验名称：Cytotoxicity against LPS-induced mouse BV2 cells assessed as cell viability after 24 ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3830043

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灵芝醇B英文别名

• ganoderol B
• (3β,24E)-Lanosta-7,9(11),24-triene-3,26-diol
• Ganodermadiol