盐酸鲁氟沙星(MF-934)结构式
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常用名 | 盐酸鲁氟沙星(MF-934) | 英文名 | Rufloxacin (hydrochloride) |
|---|---|---|---|---|
| CAS号 | 106017-08-7 | 分子量 | 399.86700 | |
| 密度 | N/A | 沸点 | 574.6ºC at 760mmHg | |
| 分子式 | C17H19ClFN3O3S | 熔点 | 322-324ºC | |
| MSDS | N/A | 闪点 | 301.3ºC |
盐酸鲁氟沙星(MF-934)用途Rufloxacin hydrochloride (MF-934 hydrochloride) 是一种喹诺酮类抗菌剂,作用于人单核细胞,抑制B细胞分化, 且制剂拓扑异构酶抑。 |
| 中文名 | 盐酸芦氟沙星 |
|---|---|
| 英文名 | rufloxacin hydrochloride |
| 中文别名 | 2,3-二氢-9-氟-10-(4-甲基-1-哌嗪基)-7-氧代-7H-吡啶并[1,2,3-de][1,4]苯并噻嗪-6-羧酸盐酸盐 |
| 英文别名 | 更多 |
| 沸点 | 574.6ºC at 760mmHg |
|---|---|
| 熔点 | 322-324ºC |
| 分子式 | C17H19ClFN3O3S |
| 分子量 | 399.86700 |
| 闪点 | 301.3ºC |
| 精确质量 | 399.08200 |
| PSA | 91.08000 |
| LogP | 2.50120 |
| InChIKey | LPQOADBMXVRBNX-UHFFFAOYSA-N |
| SMILES | CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c3c2SCC4)CC1.Cl |
| 储存条件 | 2-8℃ |
| 海关编码 | 2942000000 |
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~71%
盐酸鲁氟沙星(MF-934) 106017-08-7 |
| 文献:Mediolanum Farmaceutici S.p.A. Patent: US5221741 A1, 1993 ; |
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~88%
盐酸鲁氟沙星(MF-934) 106017-08-7 |
| 文献:Cecchetti; Fravolini; Schiaffella Synthetic Communications, 1991 , vol. 21, # 22 p. 2301 - 2308 |
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~%
盐酸鲁氟沙星(MF-934) 106017-08-7 |
| 文献:Synthetic Communications, , vol. 21, # 22 p. 2301 - 2308 |
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~%
盐酸鲁氟沙星(MF-934) 106017-08-7 |
| 文献:Synthetic Communications, , vol. 21, # 22 p. 2301 - 2308 |
|
~%
盐酸鲁氟沙星(MF-934) 106017-08-7 |
| 文献:Synthetic Communications, , vol. 21, # 22 p. 2301 - 2308 |
| 盐酸鲁氟沙星(MF-934)上游产品 4 | |
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| 盐酸鲁氟沙星(MF-934)下游产品 0 | |
| 海关编码 | 2942000000 |
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实验名称:Luminescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id:OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
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实验名称:Primary qHTS assay for inhibitors of alpha-synuclein gene (SNCA) expression
来源:NCGC
External Id:SNCA-p-activity-luciferase
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify ago...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_AG_FLUO8_1536_1X%ACT PRUN
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实验名称:Cytochrome P450 Family 1 Subfamily A Member 2 (CYP1A2) small molecule antagonists: lu...
来源:824
External Id:CYP273
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实验名称:Antibacterial activity against Staphylococcus aureus MRSA ATCC 43300 (CO-ADD:GP_020);...
来源:ChEMBL
靶标:Staphylococcus aureus
External Id:CHEMBL4296184
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实验名称:Antibacterial activity against Klebsiella pneumoniae MDR ATCC 70063 (CO-ADD:GN_003); ...
来源:ChEMBL
靶标:Klebsiella pneumoniae
External Id:CHEMBL4296186
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实验名称:Antibacterial activity against Escherichia coli ATCC 25922 (CO-ADD:GN_001); MIC in CA...
来源:ChEMBL
靶标:Escherichia coli
External Id:CHEMBL4296185
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实验名称:Fluorescence-based cell-based primary high throughput screening assay to identify pos...
来源:The Scripps Research Institute Molecular Screening Center
靶标:muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id:CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
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实验名称:Fluorescence polarization-based biochemical high throughput primary assay to identify...
来源:The Scripps Research Institute Molecular Screening Center
靶标:RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id:SIAE_INH_FP_1536_1X%INH PRUN
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实验名称:p53 small molecule agonists, cell-based qHTS assay: qHTS cell viability counter scree...
来源:824
靶标:N/A
External Id:P53600
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| 7H-Pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylicacid,9-fluoro-2,3-dihydro-10-(4-methyl-1-piperazinyl)-7-oxo-,hydrochloride(1:1) |
| MF-934 |
| MFCD00912283 |
| 9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de][1,4]benzothiazine-6-carboxylic acid hydrochloride |
| 7H-Pyrido(1,2,3-de)(1,4)benzothiazine-6-carboxylic acid,2,3-dihydro-9-fluoro-10-(4-methyl-1-piperazinyl)-7-oxo-,monohydrochloride |
| Rufloxacin (hydrochloride) |