盐酸去甲乌药碱

• 常用名: 盐酸去甲乌药碱
• 英文名: Higenamine HCl
• CAS号: 11041-94-4
• 分子量: 307.772
• 密度: N/A
• 沸点: 522.4ºC at 760 mmHg
• 分子式: C₁₆H₁₈ClNO₃
• 熔点: N/A
• 闪点: 209.6ºC

盐酸去甲乌药碱用途

Higenamine hydrochloride (Norcoclaurine hydrochloride) 是一种 β2-AR 激动剂,是东亚国家治疗心力衰竭的中药乌头的关键成分。Higenamine hydrochloride (Norcoclaurine hydrochloride) 具有抗凋亡作用。

盐酸去甲乌药碱名称

• 中文名: 盐酸去甲乌头碱
• 英文名: 1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydro-6,7-isoquinolinediol hydro chloride (1:1)
• 中文别名: 1-(4-羟基苄基)-6,7-二羟基-1,2,3,4-四氢异喹啉盐酸盐 | 盐酸去甲乌药碱 | 去甲乌药碱盐酸盐 | 6,7-二羟基-1-(4-羟基苄基)-1,2,3,4-四氢异喹啉盐酸盐

盐酸去甲乌药碱生物活性

• 描述: Higenamine hydrochloride (Norcoclaurine hydrochloride) 是一种 β2-AR 激动剂,是东亚国家治疗心力衰竭的中药乌头的关键成分。Higenamine hydrochloride (Norcoclaurine hydrochloride) 具有抗凋亡作用。
• 相关类别:
  信号通路 >> 细胞凋亡 >> 细胞凋亡
  研究领域 >> 癌症
  研究领域 >> 内分泌
• 靶点实验:

  β2-AR[1]

• 参考文献:

  [1]. Wu MP, et al. Higenamine protects ischemia/reperfusion induced cardiac injury and myocyte apoptosis through activation of β2-AR/PI3K/AKT signaling pathway. Pharmacol Res. 2016 Feb;104:115-23.

  [2]. Lee SR, et al. Acute oral intake of a higenamine-based dietary supplement increases circulating free fatty acidsand energy expenditure in human subjects. Lipids Health Dis. 2013 Oct 21;12:148.

盐酸去甲乌药碱物理化学性质

• 沸点: 522.4ºC at 760 mmHg
• 分子式: C₁₆H₁₈ClNO₃
• 分子量: 307.772
• 闪点: 209.6ºC
• 精确质量: 307.097534
• PSA: 72.72000
• LogP: 3.36370
• InChIKey: SWWQQSDRUYSMAR-UHFFFAOYSA-N
• SMILES: Cl.Oc1ccc(CC2NCCc3cc(O)c(O)cc32)cc1
• 蒸汽压: 1.56E-11mmHg at 25°C
• 储存条件: 室温，干燥

盐酸去甲乌药碱毒性和生态

盐酸去甲乌药碱安全信息

• 海关编码: 2933499090

盐酸去甲乌药碱海关

• 海关编码: 2933499090
• 中文概述: 2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
• Summary: 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

盐酸去甲乌药碱靶点实验

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盐酸去甲乌药碱英文别名

• pyrido[3,4-e][1,2,4]triazolo[1,5-a]pyrimidin-6(7H)-one
• 1-(4-Hydroxybenzyl)-1,2,3,4-tetrahydro-6,7-isoquinolinediol hydrochloride (1:1)
• 6,7-dihydroxy-1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline hydrochloride
• Higenamine HCl
• UNII:PQ432PID6E
• 6,7-Isoquinolinediol, 1,2,3,4-tetrahydro-1-[(4-hydroxyphenyl)methyl]-, hydrochloride (1:1)