菲律宾菌素复合体

更新时间：2025-08-25 17:00:04

菲律宾菌素复合体结构式	常用名	菲律宾菌素复合体	英文名	Filipin complex
	CAS号	11078-21-0	分子量	654.82800
	密度	1.161 g/cm3	沸点	913.9ºC at 760 mmHg
	分子式	C₃₅H₅₈O₁₁(forFilipinIII)	熔点	N/A
	MSDS	中文版美版	闪点	279.3ºC
	符号	GHS07	信号词	Warning

菲律宾菌素复合体用途

Filipin 在自然界中被称为 Filipin complex (Filipins I-IV),Filipin 是一种28-元环五烯大环内酯类抗真菌抗生素,由 S. filipinensis,S. avermitilis 和 S. miharaensis 产生。Filipin 可以与膜甾醇相互作用导致膜结构的改变。Filipin III 是 Filipin 的主要成分。

中文名	非律平
英文名	Filipin complex from Streptomyces filipinensis
英文别名	更多

描述	Filipin 在自然界中被称为 Filipin complex (Filipins I-IV),Filipin 是一种28-元环五烯大环内酯类抗真菌抗生素,由 S. filipinensis,S. avermitilis 和 S. miharaensis 产生。Filipin 可以与膜甾醇相互作用导致膜结构的改变。Filipin III 是 Filipin 的主要成分。
相关类别	研究领域 >> 其他信号通路 >> 抗感染 >> 真菌
参考文献	[1]. Kelly PM, et al. Separation of the filipin complex by gradient-elution high performance liquid chromatography. J Antibiot (Tokyo). 1985 Apr;38(4):485-9. [2]. Payero TD, et al. Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivatives. Microb Cell Fact. 2015 Aug 7;14:114.

描述

相关类别

研究领域 >> 其他

信号通路 >> 抗感染 >> 真菌

参考文献

[1]. Kelly PM, et al. Separation of the filipin complex by gradient-elution high performance liquid chromatography. J Antibiot (Tokyo). 1985 Apr;38(4):485-9.

[2]. Payero TD, et al. Functional analysis of filipin tailoring genes from Streptomyces filipinensis reveals alternative routes in filipin III biosynthesis and yields bioactive derivatives. Microb Cell Fact. 2015 Aug 7;14:114.

密度	1.161 g/cm3
沸点	913.9ºC at 760 mmHg
分子式	C₃₅H₅₈O₁₁(forFilipinIII)
分子量	654.82800
闪点	279.3ºC
精确质量	654.39800
PSA	208.37000
LogP	1.88800
InChIKey	IMQSIXYSKPIGPD-UHFFFAOYSA-N
SMILES	CCCCCC(O)C1C(=O)OC(C)C(O)C=CC=CC=CC=CC=C(C)C(O)CC(O)CC(O)CC(O)CC(O)CC(O)CC1O
外观性状	淡黄色至黄褐色的粉末
储存条件	-20°C

菲律宾菌素复合体毒性英文版

符号	GHS07
信号词	Warning
危害声明	H315-H319-H335
警示性声明	P261-P305 + P351 + P338
危害码 (欧洲)	Xn: Harmful;Xi: Irritant;
风险声明 (欧洲)	R36/37/38
安全声明 (欧洲)	26-36
危险品运输编码	NONH for all modes of transport

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(3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,1 0,12,14,16,27-Octahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethylo xacyclooctacosa-17,19,21,23,25-pentaen-2-one