PXYC12

更新时间：2025-08-27 18:43:38

PXYC12用途

PXYC12是一种核糖体蛋白S1(RpsA)拮抗剂,RpsA-CTD和RpsA-CTDΔ438A的Kds分别为2.67和4.67μM。RpsA在结核分枝杆菌(Mtb)的转译过程中起着重要作用[1]。

英文名	PXYC12

描述	PXYC12是一种核糖体蛋白S1(RpsA)拮抗剂,RpsA-CTD和RpsA-CTDΔ438A的Kds分别为2.67和4.67μM。RpsA在结核分枝杆菌(Mtb)的转译过程中起着重要作用[1]。
相关类别	研究领域 >> 感染信号通路 >> 抗感染 >> 细菌
参考文献	[1]. Yazhuang Dai, et al. Discovery and evaluation of new compounds targeting ribosomal protein S1 in antibiotic-resistant Mycobacterium Tuberculosis. Eur J Med Chem. 2020 Jun 15;196:112317.

分子式	C₁₅H₁₅N₅O₂S
分子量	329.38

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA C-terminal domain (285 to 476 res...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4768994

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA Ala438 deleted mutant C-terminal ...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4768995

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA C-terminal domain (285 to 476 res...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4768992

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA Ala438 deleted mutant C-terminal ...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4768993

实验名称：Binding affinity to Mycobacterium tuberculosis 15N-labelled wild type RpsA (280 to 43...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4768998

实验名称：qHTS assay for inhibitors of human lactate dehydrogenase
来源：NCGC
靶标：N/A
External Id：LDHA

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA C-terminal domain (285 to 476 res...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4768996

实验名称：Binding affinity to Mycobacterium tuberculosis RpsA Ala438 deleted mutant C-terminal ...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4768997

实验名称：Primary qHTS Assay for Foot and Mouth Disease Virus Antivirals against NCGC Sytravon ...
来源：NCGC
External Id：stopgo-p2-SytraCBC-dual-FF

实验名称：Primary qHTS Assay for Foot and Mouth Disease Virus Antivirals against NCGC Sytravon ...
来源：NCGC
External Id：stopgo-p2-SytraCBC-dual-Ren

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