氯吡格雷硫代内酯

• 常用名: 氯吡格雷硫代内酯
• 英文名: Clopidogrel thiolactone
• CAS号: 1147350-75-1
• 分子量: 337.821
• 密度: 1.4±0.1 g/cm3
• 沸点: 488.1±45.0 °C at 760 mmHg
• 分子式: C₁₆H₁₆ClNO₃S
• 熔点: N/A
• 闪点: 249.0±28.7 °C

氯吡格雷硫代内酯用途

Clopidogrel thiolactone是一种P2Y12受体抑制剂, 是一种有效的抗血小板药物。

氯吡格雷硫代内酯名称

• 中文名: 氯吡格雷硫代内酯
• 英文名: methyl (2S)-2-(2-chlorophenyl)-2-(2-oxo-4,6,7,7a-tetrahydrothieno[3,2-c]pyridin-5-yl)acetate

氯吡格雷硫代内酯生物活性

• 描述: Clopidogrel thiolactone是一种P2Y12受体抑制剂, 是一种有效的抗血小板药物。
• 相关类别:
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> P2Y受体
  研究领域 >> 心血管疾病
• 参考文献:

  [1]. Shan J, et al. Overcoming Clopidogrel Resistance: Discovery of Vicagrel as a Highly Potent and Orally Bioavailable Antiplatelet Agent

氯吡格雷硫代内酯物理化学性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 488.1±45.0 °C at 760 mmHg
• 分子式: C₁₆H₁₆ClNO₃S
• 分子量: 337.821
• 闪点: 249.0±28.7 °C
• 精确质量: 337.053955
• PSA: 71.91000
• LogP: 2.96
• InChIKey: JBSAZVIMJUOBNB-WUJWULDRSA-N
• SMILES: COC(=O)C(c1ccccc1Cl)N1CCC2SC(=O)C=C2C1
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.640
• 储存条件: 2-8℃

氯吡格雷硫代内酯安全信息

• 海关编码: 2934999090

氯吡格雷硫代内酯海关

• 海关编码: 2934999090
• 中文概述: 2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
• 申报要素: 品名, 成分含量, 用途
• Summary: 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

氯吡格雷硫代内酯靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Primary Screen for Target Class Profiling of Small Molecule Inhibitors of Methyltrans... 来源：NCGC External Id：MTASE-p

实验名称：Primary qHTS to identify gynecologic anti-cancer compounds using libraries of approve... 来源：NCGC 靶标：N/A External Id：OBG420

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-2C

实验名称：Primary qHTS for inhibitors of nuclear receptor binding SET domain protein 2 (NSD2) i... 来源：NCGC External Id：NSD2-synergy-p-9B

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) drug resistant ... 来源：NCGC External Id：s-sky_synergy-MV-411_DR-CTG72-MIPE_NPC_NPACT_Kinase-p1

实验名称：Viability qHTS for spleen associated tyrosine kinase inhibitor (SYKi) naive MV4-11 ce... 来源：NCGC External Id：s-sky_synergy-MV-411_N-CTG72-MIPE_NPC_NPACT_Kinase-p1

实验名称：Antiplatelet activity in Wistar rat assessed as inhibition of ADP-induced platelet ag... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2045694

实验名称：Drug metabolism in human liver microsome assessed as (E)-2-(1-((S)-1-(2-chlorophenyl)... 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3541586

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

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氯吡格雷硫代内酯英文别名

• (S)-methyl 2-(2-chlorophenyl)-2-(2-oxo-7,7a-dihydrothieno-[3,2-c]pyridin-5(2H,4H,6H)-yl)acetate
• (2S)-Methyl 2-(2-chlorophenyl)-2-(2-oxo-7,7a-dihydrothieno[3,2-c]pyridin-5(2H,4H,6H)-yl)acetate
• (2'S)-2-oxo-clopidogrel
• [8S]-2-oxo-clopidogrel
• clopidogrel thiolactone
• Methyl (2S)-(2-chlorophenyl)(2-oxo-2,6,7,7a-tetrahydrothieno[3,2-c]pyridin-5(4H)-yl)acetate
• (2S)-methyl 2-(2-oxo-7,7a-dihydrothieno[3,2-c]pyridin-5(2H,4H,6H)-yl)-2-(2-chlorophenyl)acetate
• 2-Oxoclopidogrel
• methyl (2'S)-2-(2-chlorophenyl)-2-(2,4,5,6,7,7a-hexahydrothieno[3,2-c]-5-pyridin-2-one)acetate