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6-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯

更新时间:2024-01-09 21:25:41

6-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯结构式
6-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯结构式
品牌特惠专场
常用名 6-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯 英文名 tert-butyl 6-cyano-5-methyl-3,4-dihydro-1H-isoquinoline-2-carboxylate
CAS号 1165923-92-1 分子量 272.34200
密度 N/A 沸点 N/A
分子式 C16H20N2O2 熔点 N/A
MSDS N/A 闪点 N/A

 名称

中文名 6-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯
英文名 tert-butyl 6-cyano-5-methyl-3,4-dihydro-1H-isoquinoline-2-carboxylate

 物理化学性质

分子式 C16H20N2O2
分子量 272.34200
精确质量 272.15200
PSA 53.33000
LogP 3.09778

 安全信息

海关编码 2933499090

 合成线路

~89%

6-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯结构式

6-氰基-5-甲基-3,4-二...

1165923-92-1

文献:Demont, Emmanuel H.; Arpino, Sandra; Bit, Rino A.; Campbell, Colin A.; Deeks, Nigel; Desai, Sapna; Dowell, Simon J.; Gaskin, Pam; Gray, James R. J.; Harrison, Lee A.; Haynes, Andrea; Heightman, Tom D.; Holmes, Duncan S.; Humphreys, Philip G.; Kumar, Umesh; Morse, Mary A.; Osborne, Greg J.; Panchal, Terry; Philpott, Karen L.; Taylor, Simon; Watson, Robert; Willis, Robert; Witherington, Jason Journal of Medicinal Chemistry, 2011 , vol. 54, # 19 p. 6724 - 6733

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6-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯结构式

6-氰基-5-甲基-3,4-二...

1165923-92-1

文献:GLAXO GROUP LIMITED Patent: WO2009/80724 A1, 2009 ; Location in patent: Page/Page column 29 ; WO 2009/080724 A1

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6-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯结构式

6-氰基-5-甲基-3,4-二...

1165923-92-1

文献:GLAXO GROUP LIMITED; BAILEY, James, Matthew; BIT, Rino, Antonio; DEMONT, Emmanuel, Hubert; HARRISON, Lee, Andrew; JONES, Katherine, Louise; SMETHURST, Christian, Alan, Paul; WITHERINGTON, Jason Patent: WO2010/146105 A1, 2010 ; WO 2010/146105 A1

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6-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯结构式

6-氰基-5-甲基-3,4-二...

1165923-92-1

文献:GLAXO GROUP LIMITED; BAILEY, James, Matthew; BIT, Rino, Antonio; DEMONT, Emmanuel, Hubert; HARRISON, Lee, Andrew; JONES, Katherine, Louise; SMETHURST, Christian, Alan, Paul; WITHERINGTON, Jason Patent: WO2010/146105 A1, 2010 ; WO 2010/146105 A1

~%

6-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯结构式

6-氰基-5-甲基-3,4-二...

1165923-92-1

文献:GLAXO GROUP LIMITED; BAILEY, James, Matthew; BIT, Rino, Antonio; DEMONT, Emmanuel, Hubert; HARRISON, Lee, Andrew; JONES, Katherine, Louise; SMETHURST, Christian, Alan, Paul; WITHERINGTON, Jason Patent: WO2010/146105 A1, 2010 ; WO 2010/146105 A1

~%

6-氰基-5-甲基-3,4-二氢异喹啉-2(1h)-羧酸叔丁酯结构式

6-氰基-5-甲基-3,4-二...

1165923-92-1

文献:GLAXO GROUP LIMITED; BAILEY, James, Matthew; BIT, Rino, Antonio; DEMONT, Emmanuel, Hubert; HARRISON, Lee, Andrew; JONES, Katherine, Louise; SMETHURST, Christian, Alan, Paul; WITHERINGTON, Jason Patent: WO2010/146105 A1, 2010 ; WO 2010/146105 A1

 海关

海关编码 2933499090
中文概述 2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素 品名, 成分含量, 用途, 乌洛托品请注明外观, 6-己内酰胺请注明外观, 签约日期
Summary 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
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