盐酸去甲左氧氟沙星

• 常用名: 盐酸去甲左氧氟沙星
• 英文名: N-Desmethyl levofloxacin
• CAS号: 117707-40-1
• 分子量: 347.34100
• 密度: 1.517g/cm3
• 沸点: 600.714ºC at 760 mmHg
• 分子式: C₁₇H₁₈FN₃O₄
• 熔点: N/A
• 闪点: 317.101ºC
• 符号: GHS07
• 信号词: Warning

盐酸去甲左氧氟沙星用途

Desmethyl Levofloxacin 是 Levofloxacin 的代谢物。Levofloxacin 是合成的氟喹诺酮类抗生素,能抑制细菌 DNA 旋转酶的超螺旋活性,可阻止 DNA 复制。

盐酸去甲左氧氟沙星名称

• 中文名: 9-氟-3-甲基-7-氧代-10-(1-哌嗪基)-2,3-二氢-7H-[1,4]恶嗪并[2,3,4-Ij]喹啉-6-羧酸
• 英文名: S-(-)-9-fluoro-2,3-dihydro-3-methyl-10-(1-piperazinyl)-7-oxo-7H-pyrido-<1,2,3-de><1,4>benzoxazine-6-carboxylic acid
• 中文别名: N-脱甲基左氧氟沙星 | 盐酸去甲左氧氟沙星

盐酸去甲左氧氟沙星生物活性

• 描述: Desmethyl Levofloxacin 是 Levofloxacin 的代谢物。Levofloxacin 是合成的氟喹诺酮类抗生素,能抑制细菌 DNA 旋转酶的超螺旋活性,可阻止 DNA 复制。
• 相关类别:
  研究领域 >> 感染
• 参考文献:

  [1]. Siva, R., et al., Effect of levofloxacin on neutrophilic airway inflammation in stable COPD: a randomized, double-blind, placebo-controlled trial. Int J Chron Obstruct Pulmon Dis, 2014. 9: p. 179-86.

盐酸去甲左氧氟沙星物理化学性质

• 密度: 1.517g/cm3
• 沸点: 600.714ºC at 760 mmHg
• 分子式: C₁₇H₁₈FN₃O₄
• 分子量: 347.34100
• 闪点: 317.101ºC
• 精确质量: 347.12800
• PSA: 83.80000
• LogP: 1.59560
• InChIKey: WKRSSAPQZDHYRV-VIFPVBQESA-N
• SMILES: CC1COc2c(N3CCNCC3)c(F)cc3c(=O)c(C(=O)O)cn1c23
• 蒸汽压: 0mmHg at 25°C
• 折射率: 1.677

盐酸去甲左氧氟沙星安全信息

• 符号: GHS07
• 信号词: Warning
• 危害声明: H302
• 危害码 (欧洲): Xn
• 风险声明 (欧洲): 22
• 危险品运输编码: NONH for all modes of transport

盐酸去甲左氧氟沙星靶点实验

查看更多实验

实验名称：Antibacterial activity against Klebsiella pneumoniae ATCC 10031 after 18 hrs by agar ... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL3077690

实验名称：Antibacterial activity against Pseudomonas aeruginosa ATCC 9027 after 18 hrs by agar ... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL3077691

实验名称：Antibacterial activity against Bacillus subtilis ATCC 6633 after 18 hrs by agar dilut... 来源：ChEMBL 靶标：Bacillus subtilis External Id：CHEMBL3077692

实验名称：Antibacterial activity against Staphylococcus epidermidis ATCC 12228 after 18 hrs by ... 来源：ChEMBL 靶标：Staphylococcus epidermidis External Id：CHEMBL3077693

实验名称：Antibacterial activity against Staphylococcus aureus ATCC 6538 after 18 hrs by agar d... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL3077694

实验名称：Bacteriostatic activity against Escherichia coli K-12 DM4100 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL1691259

实验名称：Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL892637

实验名称：Primary high throughput screening by co-culture imaging for identification hits as a ... 来源：23209 靶标：N/A External Id：UIHTS20180925

实验名称：Antibacterial activity against Staphylococcus aureus ATCC 6538p after 18 hrs 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL892638

实验名称：Antibacterial activity against Bacillus subtilis ATCC 6051 after 18 hrs 来源：ChEMBL 靶标：Bacillus subtilis External Id：CHEMBL892643

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盐酸去甲左氧氟沙星英文别名

• UNII-88ZBA45NC8
• Levofloxacin related compound A
• Uing 4-255
• des-methyl levofloxacin
• N-Desmethyl levofloxacin
• Levofloxacin Impurity 2