奎奴普丁

• 常用名: 奎奴普丁
• 英文名: Quinupristin
• CAS号: 120138-50-3
• 分子量: 1022.22000
• 密度: 1.38g/cm3
• 沸点: N/A
• 分子式: C₅₃H₆₇N₉O₁₀S
• 熔点: N/A
• 闪点: N/A

奎奴普丁用途

Quinupristin 是一种链球菌素类抗生素。Quinupristin 可阻断细菌核糖体亚基中肽键的合成,阻止多肽链的延伸,促进不完全蛋白链的分离。

奎奴普丁名称

• 中文名: 奎奴普丁
• 英文名: Quinupristin
• 中文别名: 喹努普丁

奎奴普丁生物活性

• 描述: Quinupristin 是一种链球菌素类抗生素。Quinupristin 可阻断细菌核糖体亚基中肽键的合成,阻止多肽链的延伸,促进不完全蛋白链的分离。
• 相关类别:
  信号通路 >> 抗感染 >> 细菌
• 体外研究: quinuprestin/dalfopristin是一种用于抗感染的链霉素抗生素的组合。quinuprestin/dalfopristin针对大多数革兰氏阳性菌和某些革兰氏阴性菌的23srrna。据报道,奎宁普列汀/达福普利汀对支原体有效[1]。
• 参考文献:

  [1]. Gurk-Turner C. Quinupristin/dalfopristin: the first available macrolide-lincosamide-streptogramin antibiotic. Proc (Bayl Univ Med Cent). 2000 Jan;13(1):83-6.

  [2]. Tantibhedhyangkul W, et al. Anti-Mycoplasma Activity of Daptomycin and Its Use for Mycoplasma Elimination in Cell Cultures of Rickettsiae. Antibiotics (Basel). 2019 Aug 21;8(3).

奎奴普丁物理化学性质

• 密度: 1.38g/cm3
• 分子式: C₅₃H₆₇N₉O₁₀S
• 分子量: 1022.22000
• 精确质量: 1021.47000
• PSA: 256.50000
• LogP: 3.12360
• InChIKey: WTHRRGMBUAHGNI-KNIYECGFSA-N
• SMILES: CCC1NC(=O)C(NC(=O)c2ncccc2O)C(C)OC(=O)C(c2ccccc2)NC(=O)C2CC(=O)C(CSC3CN4CCC3CC4)CN2C(=O)C(Cc2ccc(N(C)C)cc2)N(C)C(=O)C2CCCN2C1=O
• 折射率: 1.662
• 储存条件: -20°C，密闭，干燥

奎奴普丁靶点实验

查看更多实验

实验名称：Inhibition of mitochondrial translation in human COMI cells assessed as increase in C... 来源：ChEMBL 靶标：COMI External Id：CHEMBL5332877

实验名称：Inhibition of mitochondrial translation in human COMI cells assessed as decrease in C... 来源：ChEMBL 靶标：COMI External Id：CHEMBL5332875

实验名称：Inhibition of mitochondrial translation in human COMI cells assessed as decrease in C... 来源：ChEMBL 靶标：COMI External Id：CHEMBL5332876

实验名称：Inhibition of mitochondrial translation in human COMI cells assessed as decrease in N... 来源：ChEMBL 靶标：COMI External Id：CHEMBL5332874

实验名称：Antimicrobial activity against methicillin resistant Staphylococcus aureus 181404 ass... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL5536042

实验名称：Inhibition of mitochondrial translation in human COMI cells assessed as decrease in C... 来源：ChEMBL 靶标：COMI External Id：CHEMBL5332869

实验名称：Antimicrobial activity against vancomycin resistant Enterococcus faecium 310682 asses... 来源：ChEMBL 靶标：Enterococcus faecium External Id：CHEMBL5536041

实验名称：Antimicrobial activity against Staphylococcus aureus ATCC 29213 assessed as inhibitio... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL5536040

实验名称：Inhibition of mitochondrial translation in human COMI cells assessed as decrease in N... 来源：ChEMBL 靶标：COMI External Id：CHEMBL5332867

实验名称：Antimicrobial activity against Enterococcus faecium ATCC 35667 assessed as inhibition... 来源：ChEMBL 靶标：Enterococcus faecium External Id：CHEMBL5536039

共60条，当前第1页，共6页

1

2

3

4

5