Topoisomerase I inhibitor 9

• 常用名: Topoisomerase I inhibitor 9
• 英文名: Topoisomerase I inhibitor 9
• CAS号: 1228150-86-4
• 分子量: 498.19
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₁₅Br₂FN₂
• 熔点: N/A
• 闪点: N/A

Topoisomerase I inhibitor 9用途

Topoisomerase I inhibitor 9 (compound 3d) 是一种 leishmanial topoisomerase IB 抑制剂。Topoisomerase I inhibitor 9 对 L. donovani promastigotes 具有抗利什曼原虫活性,其 IC50 > 值为 34.81 μM。

Topoisomerase I inhibitor 9名称

• 英文名: Topoisomerase I inhibitor 9

Topoisomerase I inhibitor 9生物活性

• 描述: Topoisomerase I inhibitor 9 (compound 3d) 是一种 leishmanial topoisomerase IB 抑制剂。Topoisomerase I inhibitor 9 对 L. donovani promastigotes 具有抗利什曼原虫活性,其 IC50 > 值为 34.81 μM。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> 拓扑异构酶
  研究领域 >> 感染
• 靶点实验:

  34.81 μM[1]

• 参考文献:

  [1]. Kour P, et al. Design, synthesis, and biological evaluation of 3,3'-diindolylmethane N-linked glycoconjugate as a leishmanial topoisomerase IB inhibitor with reduced cytotoxicity. RSC Med Chem. 2023;14(10):2100-2114. Published 2023 Aug 30.

Topoisomerase I inhibitor 9物理化学性质

• 分子式: C₂₃H₁₅Br₂FN₂
• 分子量: 498.19

Topoisomerase I inhibitor 9靶点实验

查看更多实验

实验名称：Antileishmanial activity against Leishmania donovani MHOM/IN/80/Dd8 promastigotes ass... 来源：ChEMBL 靶标：Leishmania donovani External Id：CHEMBL5330117

实验名称：Cytotoxicity against mouse J774.A1 cells assessed as reduction in viability at 50 uM ... 来源：ChEMBL 靶标：J774.A1 External Id：CHEMBL5330118

实验名称：Antibacterial activity against Staphylococcus aureus ATCC 29213 after 24 hrs by micro... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL2432159

实验名称：Bactericidal activity against vancomycin-resistant Enterococcus faecalis after 24 hrs 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL2432154

实验名称：Antibacterial activity against Escherichia coli ATCC 25922 after 24 hrs by microdilut... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL2432153

实验名称：Antibacterial activity against Pseudomonas aeruginosa ATCC 27853 after 24 hrs by micr... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL2432152

实验名称：Cytotoxicity against human PC3 cells after 48 hrs by MTT assay 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL2434527

实验名称：Antibacterial activity against methicillin-resistant Staphylococcus aureus after 24 h... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL2432158

实验名称：Antibacterial activity against vancomycin-resistant Enterococcus faecalis after 24 hr... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL2432157

实验名称：Bactericidal activity against Staphylococcus aureus ATCC 29213 after 24 hrs 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL2432156

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