Mitapivat

• 常用名: Mitapivat
• 英文名: Mitapivat
• CAS号: 1260075-17-9
• 分子量: 450.55300
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₂₆N₄O₃S
• 熔点: N/A
• 闪点: N/A

Mitapivat用途

Mitapivat是R型丙酮酸激酶(PKR)有效抑制剂，对突变型PKR也有抑制活性。

Mitapivat名称

• 中文名: Mitapivat
• 英文名: N-(4-(4-(cyclopropylmethyl)piperazine-1-carbonyl)phenyl)quinoline-8-sulfonamide

Mitapivat生物活性

• 描述: Mitapivat是R型丙酮酸激酶(PKR)有效抑制剂,对突变型PKR也有抑制活性。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 癌症
• 参考文献:

  [1]. PYRUVATE KINASE ACTIVATORS FOR USE IN THERAPY. Patent WO/2012/151451A1

Mitapivat物理化学性质

• 分子式: C₂₄H₂₆N₄O₃S
• 分子量: 450.55300
• 精确质量: 450.17300
• PSA: 90.99000
• LogP: 4.23300
• 储存条件: -20°C，密闭，干燥

Mitapivat靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Cellular viability qHTS for adrenocortical cancer (ACC) cell line SW-13 来源：NCGC 靶标：N/A External Id：ACC-ATC-p1-SW13-72hr

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Cellular viability qHTS for adrenocortical cancer (ACC) cell line NCI-H295R 来源：NCGC 靶标：N/A External Id：ACC-ATC-p1-H295R-72hr

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：Cytochrome P450 family 3 subfamily A member 7 (CYP3A7) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A7681

实验名称：Primary qHTS for inhibitors of NSP2Pro chikungunya virus (CHIKV) 来源：NCGC External Id：APP-Toga-CHIKV-nsp2-p

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Mitapivat英文别名

• PKM2 activator 1020
• Mitapivat