SARS-CoV-2-IN-20

• 常用名: SARS-CoV-2-IN-20
• 英文名: SARS-CoV-2-IN-20
• CAS号: 1260244-33-4
• 分子量: 378.51
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₃₀N₂O₂
• 熔点: N/A
• 闪点: N/A

SARS-CoV-2-IN-20用途

SARS-CoV-2-IN-20(化合物1a)是一种有效的SARS-CoV-2抑制剂,EC50为6.5μM。SARS-CoV-2-IN-20具有研究感染性疾病的潜力【1】。

SARS-CoV-2-IN-20名称

• 英文名: SARS-CoV-2-IN-20

SARS-CoV-2-IN-20生物活性

• 描述: SARS-CoV-2-IN-20(化合物1a)是一种有效的SARS-CoV-2抑制剂,EC50为6.5μM。SARS-CoV-2-IN-20具有研究感染性疾病的潜力【1】。
• 相关类别:
  研究领域 >> 感染
  信号通路 >> 抗感染 >> SARS冠状病毒
• 参考文献:

  [1]. Nizi MG, et al. Discovery of 2-Phenylquinolines with Broad-Spectrum Anti-coronavirus Activity. ACS Med Chem Lett. 2022 May 3;13(5):855-864.

SARS-CoV-2-IN-20物理化学性质

• 分子式: C₂₄H₃₀N₂O₂
• 分子量: 378.51

SARS-CoV-2-IN-20靶点实验

查看更多实验

实验名称：Antimicrobial activity against Staphylococcus aureus ATCC 25923 by microdilution meth... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4151525

实验名称：Inhibition of NorA in Staphylococcus aureus K2378 bearing norA++ efficient mutation a... 来源：ChEMBL 靶标：Quinolone resistance protein NorA External Id：CHEMBL1817273

实验名称：Inhibition of wild-type norA expressing Staphylococcus aureus 1199 assessed as reduct... 来源：ChEMBL 靶标：Quinolone resistance protein NorA External Id：CHEMBL1817275

实验名称：Antimicrobial activity against Staphylococcus aureus SA-1199B expressing wild type no... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4151528

实验名称：Synergistic potentiation of ciprofloxacin-induced antimicrobial activity against norA... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4151521

实验名称：Inhibition of NorA in Staphylococcus aureus 1199B norA++ and A116E GrlA mutation asse... 来源：ChEMBL 靶标：Quinolone resistance protein NorA External Id：CHEMBL1817276

实验名称：Cytotoxicity in human HepG2 cells assessed as reduction in cell viability incubated f... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL4151523

实验名称：Potentiation of ciprofloxacin-antibacterial activity against Staphylococcus aureus K1... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL1817279

实验名称：Cytotoxicity in human THP1 cells assessed as reduction in cell viability incubated fo... 来源：ChEMBL 靶标：THP-1 External Id：CHEMBL4151524

实验名称：Antimicrobial activity against NorA deficient Staphylococcus aureus SA-K1902 by micro... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL4151529

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