N-palmitoylserinol

• 常用名: N-palmitoylserinol
• 英文名: N-palmitoylserinol
• CAS号: 126127-31-9
• 分子量: 329.518
• 密度: 1.0±0.1 g/cm3
• 沸点: 525.9±40.0 °C at 760 mmHg
• 分子式: C₁₉H₃₉NO₃
• 熔点: N/A
• 闪点: 271.9±27.3 °C

N-palmitoylserinol用途

棕榈酰丝氨酸醇(N-棕榈酰丝氨酸醇)是内源性大麻素N-棕榈酰乙醇胺(PEA)的类似物。棕榈酰丝氨酸醇改善正常和炎症皮肤的表皮渗透屏障[1][2]。

N-palmitoylserinol名称

• 英文名: N-(1,3-dihydroxypropan-2-yl)hexadecanamide

N-palmitoylserinol生物活性

• 描述: 棕榈酰丝氨酸醇(N-棕榈酰丝氨酸醇)是内源性大麻素N-棕榈酰乙醇胺(PEA)的类似物。棕榈酰丝氨酸醇改善正常和炎症皮肤的表皮渗透屏障[1][2]。
• 相关类别:
  研究领域 >> 炎症/免疫
  信号通路 >> G 蛋白偶联受体/G 蛋白 >> 大麻素受体
• 体外研究: 棕榈酰丝氨酸醇(N-棕榈酰丝氨酸醇)在体外皮肤炎症模型中通过CB1依赖机制刺激神经酰胺的产生[2]。
• 参考文献:

  [1]. Shin KO, et al. N-Palmitoyl Serinol Stimulates Ceramide Production through a CB1-Dependent Mechanism in In Vitro Model of Skin Inflammation. Int J Mol Sci. 2021;22(15):8302. Published 2021 Aug 2.

N-palmitoylserinol物理化学性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 525.9±40.0 °C at 760 mmHg
• 分子式: C₁₉H₃₉NO₃
• 分子量: 329.518
• 闪点: 271.9±27.3 °C
• 精确质量: 329.292999
• PSA: 69.56000
• LogP: 5.68
• InChIKey: MZUNFYMZKTWADX-UHFFFAOYSA-N
• SMILES: CCCCCCCCCCCCCCCC(=O)NC(CO)CO
• 蒸汽压: 0.0±3.1 mmHg at 25°C
• 折射率: 1.475

N-palmitoylserinol靶点实验

查看更多实验

实验名称：Discovery of Small Molecules to Inhibit Human Cytomegalovirus Nuclear Egress 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：HCMV UL50 External Id：HMS1262

实验名称：A screen for small molecules that modulate mitochondrial supercomplex formation 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1482

实验名称：Cell-based high throughput primary assay to identify activators of GPR151 来源：The Scripps Research Institute Molecular Screening Center 靶标：RecName: Full=G-protein coupled receptor 151; AltName: Full=G-protein coupled receptor PGR7; AltName: Full=GPCR-2037; AltName: Full=Galanin receptor 4; AltName: Full=Galanin-receptor-like protein; Short=GalRL External Id：GPR151_PHUNTER_AG_LUMI_1536_1X%ACT

实验名称：AlphaScreen-based biochemical high throughput primary assay to identify inhibitors of... 来源：The Scripps Research Institute Molecular Screening Center External Id：MITF_INH_Alpha_1536_1X%INH PRUN

实验名称：Stabilization of p53 in human papillomavirus-positive cells 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1485

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

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N-palmitoylserinol英文别名

• N-(1,3-Dihydroxy-2-propanyl)hexadecanamide
• N-palmitoylserinol
• Palmitoyl Serinol
• N-palmitoyl serinol