MUT056399

更新时间：2026-08-01 15:49:15

MUT056399结构式	常用名	MUT056399	英文名	MUT056399
	CAS号	1269055-85-7	分子量	293.265
	密度	1.3±0.1 g/cm3	沸点	373.8±42.0 °C at 760 mmHg
	分子式	C₁₅H₁₃F₂NO₃	熔点	N/A
	MSDS	N/A	闪点	179.9±27.9 °C

MUT056399用途

MUT056399高效抑制金黄色葡萄球菌和大肠杆菌FabI酶, IC50值分别为12 nM和58 nM。

中文名	MUT056399
英文名	MUT056399
英文别名	更多

描述	MUT056399高效抑制金黄色葡萄球菌和大肠杆菌FabI酶, IC50值分别为12 nM和58 nM。
相关类别	信号通路 >> 抗感染 >> 细菌研究领域 >> 感染
参考文献	[1]. Escaich S, et al. The MUT056399 inhibitor of FabI is a new antistaphylococcal compound. Antimicrob Agents Chemother. 2011 Oct;55(10):4692-7. [2]. Schiebel J, et al. An ordered water channel in Staphylococcus aureus FabI: unraveling the mechanism of substrate recognitionand reduction. Biochemistry. 2015 Mar 17;54(10):1943-55.

描述

MUT056399高效抑制金黄色葡萄球菌和大肠杆菌FabI酶, IC50值分别为12 nM和58 nM。

相关类别

信号通路 >> 抗感染 >> 细菌

研究领域 >> 感染

参考文献

[1]. Escaich S, et al. The MUT056399 inhibitor of FabI is a new antistaphylococcal compound. Antimicrob Agents Chemother. 2011 Oct;55(10):4692-7.

[2]. Schiebel J, et al. An ordered water channel in Staphylococcus aureus FabI: unraveling the mechanism of substrate recognitionand reduction. Biochemistry. 2015 Mar 17;54(10):1943-55.

密度	1.3±0.1 g/cm3
沸点	373.8±42.0 °C at 760 mmHg
分子式	C₁₅H₁₃F₂NO₃
分子量	293.265
闪点	179.9±27.9 °C
精确质量	293.086365
LogP	3.58
蒸汽压	0.0±0.9 mmHg at 25°C
折射率	1.584
储存条件	2-8℃

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